Cellular Immnunity
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1. Envolvimento de sinais co-estimulatórios na progressão das doenças periodontais humanas / Differential expression of costimulatory molecules in human periodontal diseases
Negative co-stimulatory signals mediated via cell surface molecules such as cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) and programmed death-1 (PD-1) play a critical role in down-modulation immune responses and maintaining peripheral tolerance. Both CTLA-4 and PD-1 are induced on activated T cells, and these are involved in the immunopathogenesis of
Publicado em: 2007