Cellular Uptake
Mostrando 1-12 de 977 artigos, teses e dissertações.
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1. Nanotechnology for the treatment of deep endometriosis: uptake of lipid core nanoparticles by LDL receptors in endometriotic foci
OBJECTIVE: Rapidly dividing cells in multiple types of cancer and inflammatory diseases undergo high low density lipoprotein (LDL) uptake for membrane synthesis, and coupling an LDL-like nanoemulsion, containing lipid nanoparticles (LDE) to a chemotherapeutic agent efficiently targets these cells without significant systemic effects. This was a prospective
Clinics. Publicado em: 10/07/2019
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2. Regulation of gene expression: Cryptic β-glucoside (bgl) operon of Escherichia coli as a paradigm
Bacteria have evolved various mechanisms to extract utilizable substrates from available resources and consequently acquire fitness advantage over competitors. One of the strategies is the exploitation of cryptic cellular functions encoded by genetic systems that are silent under laboratory conditions, such as the bgl (β-glucoside) operon of E. coli. The bg
Braz. J. Microbiol.. Publicado em: 2014-12
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3. Follow-up of patients treated with retinoic acid for the control of radioiodine non-responsive advanced thyroid carcinoma
During thyroid tumor progression, cellular de-differentiation may occur and it is commonly accompanied by metastatic spread and loss of iodine uptake. Retinoic acid (RA) administration might increase iodine uptake in about 40% of patients, suggesting that RA could be a promising therapeutic option for radioiodine non-responsive thyroid carcinoma, although a
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-01
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4. Effect of Phytoaccumulation of Arsenic and Chromium on Structural and Ultrastructural Changes of Brake Fern (Pteris vittata)
Structural and ultrastructural changes caused by bioaccumulation of As and Cr in brake fern (Pteris vittata), a known arsenic hyperaccumulator, were investigated. Potted plants of brake fern were exposed to metal treatments of As and Cr for three weeks. Leaf, stem and root samples were collected periodically and fixed for LM (Light Microscopy), SEM (Scanning
Brazilian Journal of Plant Physiology. Publicado em: 2011
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5. Papel dos receptores B1 e B2 de bradicinina e de captopril nas interações célula hospedeira-Trypanosoma cruzi
The infection of monocytes by Trypanosoma cruzi tripomastigotes is a crucial step for the development of Chagas disease immune response. Infection by T. cruzi has demonstrated to be an active process, involving diverse cellular components and different cell types. Previous studies of the interaction tissue-culture derived trypomastigotes (TCT) between cardio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/08/2010
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6. Modulation of ROS production in human leukocytes by ganglioside micelles
Recent studies have reported that exogenous gangliosides, the sialic acid-containing glycosphingolipids, are able to modulate many cellular functions. We examined the effect of micelles of mono- and trisialoganglioside GM1 and GT1b on the production of reactive oxygen species by stimulated human polymorphonuclear neutrophils using different spectroscopic met
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-10
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7. Kinetic and equilibrium study of biosorption of lead and copper ions by sargassum seaweed in nanocomponent and binary systems / Estudo cinético e do equilíbrio da biossorção dos íons chumbo e cobre pela macroalga Sargassum sp. em sistemas monocomponente e binário
Brown seaweeds from the genus Sargassum are widely studied for use as potential candidates for biosorption purposes, particularly in the treatment of heavy-metals contaminated effluents. The cellular structure of this seaweed presents charged molecules, such as alginic acid, able to attract and recover metal cation ions. The objective of this work was to stu
Publicado em: 2010
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8. Hidróxidos duplos lamelares: nanopartículas inorgânicas para armazenamento e liberação de espécies de interesse biológico e terapêutico
Studies about the inorganic nanoparticles applying for non-viral release of biological and therapeutic species have been intensified nowadays. This work reviews the preparation strategies and application of layered double hydroxides (LDH) as carriers for storing, carrying and control delivery of intercalated species as drugs and DNA for gene therapy. LDH sho
Química Nova. Publicado em: 2010
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9. Estudo dos efeitos da terapia fotodinâmica na progressão tumoral e em modelos celulares tridimensionais / Study of the effects of photodynamic therapy on tumor progression and in three-dimensional cellular models.
Melanoma is the type of skin cancer with poor prognosis due to its high probability of suffering metastases. Currently there are few effective treatments for the this, and the survival of patients with metastases is very low, around 8 months, with cure rates of these conditions do not exceed 1%. Photodynamic therapy (PDT) is a therapeutic modality selective
Publicado em: 2010
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10. Repercussões do destreinamento físico sobre o metabolismo e a celularidade do tecido adiposo branco periepididimal de ratos. / Physical detraining repercussions on metabolism and cellularity of white adipose tissue periepididymal in rats.
All adaptations acquired through physical training are reversible during inactivity. Significant reductions in maximal oxygen uptake (VO2Max) are observed within two-four weeks of detraining. Conversely, the consequences of detraining on adipose tissue are poorly known. The objective was to investigate the physical detraining effects on metabolism and cellul
Publicado em: 2010
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11. Transporte de hormônios tireoideanos em hemácias de pacientes com hipertireoidismo ou hipotireoidismo primário
Thyroid hormones (THs) have important effects on cellular growth, differentiation and metabolism. They bind to thyroid hormone receptors (TRs), which belong to the nuclear hormone receptor superfamily. Because TRs are located intracellularly, TH action requires its transport from the extracellular compartment into target cells. It has become increasingly cle
Publicado em: 2009
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12. O COMPLEXO METILMERCÚRIO-CISTEÍNA ALTERA O ACÚMULO DE MERCÚRIO EM DIFERENTES TECIDOS DE CAMUNDONGO / COMPLEX METHILMERCURY CYSTEINE ALTERS MERCURY ACCUMULATION IN DIFFERENT TISSUES OF MICE
Methylmercury (MeHg) is related to several deleterious effects on the vertebrate tissues, mainly on central nervous system, and part of these effects are through of interaction with sulfhydryl group found in cellular proteins. MeHg interacts with low and high molecular weight thiols in the blood and tissues and this fact, in some cases will allow a better ab
Publicado em: 2009