Cerebral Metabolism
Mostrando 1-12 de 178 artigos, teses e dissertações.
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1. Evaluation of 10-minute post-injection 11C-PiB PET and its correlation with 18F-FDG PET in older adults who are cognitively healthy, mildly impaired, or with probable Alzheimer’s disease
Objective: Positron emission tomography (PET) allows in vivo evaluation of molecular targets in neurodegenerative diseases, such as Alzheimer’s disease. Mild cognitive impairment is an intermediate stage between normal cognition and Alzheimer-type dementia. In vivo fibrillar amyloid-beta can be detected in PET using [11C]-labeled Pittsburgh compound B (11C
Brazilian Journal of Psychiatry. Publicado em: 2022
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2. Management of hypopituitarism: a perspective from the Brazilian Society of Endocrinology and Metabolism
ABSTRACT Hypopituitarism is a disorder characterized by insufficient secretion of one or more pituitary hormones. New etiologies of hypopituitarism have been recently described, including head trauma, cerebral hemorrhage, and drug-induced hypophysitis. The investigation of patients with these new disorders, in addition to advances in diagnosis and treatment
Arch. Endocrinol. Metab.. Publicado em: 2021-04
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3. Preserved repetition in thalamic afasia. A pathophysiological hypothesis
RESUMO. A capacidade de repetir palavras é quase sempre preservada na afasia talâmica. A fisiopatologia da afasia talâmica assim como a da preservação da repetição não são totalmente compreendidas. Em um caso de afasia grave com repetição preservada após hemorragia talâmica esquerda, a RM revelou lesão talâmica esquerda e perda de anisotropia
Dement. neuropsychol.. Publicado em: 18/06/2019
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4. Methods for quantification of cerebral glycolytic metabolism using 2-deoxy-2-[18 F]fluoroglucose in small animals
Abstract Introduction The use of the same imaging and quantification techniques in small animals and clinical studies presents the opportunity for direct translational research in drug discovery and development, in neuropharmacological basis of neurological and psychiatric diseases, and in optimization of drug therapy. Thus, positron emission tomography (P
Res. Biomed. Eng.. Publicado em: 13/09/2018
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5. Interregional correlations of glucose metabolism between the basal ganglia and different cortical areas: an ultra-high resolution PET/MRI fusion study using 18F-FDG
Basal ganglia have complex functional connections with the cerebral cortex and are involved in motor control, executive functions of the forebrain, such as the planning of movement, and cognitive behaviors based on their connections. The aim of this study was to provide detailed functional correlation patterns between the basal ganglia and cerebral cortex by
Braz J Med Biol Res. Publicado em: 13/11/2017
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6. Evidence of the Presence of Thyroid Hormones in Achatina fulica Snails
ABSTRACT The objective of this study was to identify thyroid hormones and to examine their putative site of synthesis in Achatina fulica snails. For this purpose, radioimmunoassays were performed for T3 and T4 before and after long starvation with or without hemolymph deproteinization. Sodium/iodide symporter activity in vivo was analyzed through 125I admini
An. Acad. Bras. Ciênc.. Publicado em: 24/07/2017
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7. Amyloid-β peptide absence in short term effects on kinase activity of energy metabolism in mice hippocampus and cerebral cortex
RESUMO Considerando que a doença de Alzheimer é uma doença neurodegenerativa prevalente em todo o mundo, buscou-se investigar o envolvimento da atividade de três quinases: creatinaquinase, piruvatoquinase e adenilatoquinase no hipocampo e no córtex cerebral em um modelo da doença de Alzheimer. Os camundongos Swiss, machos, adultos, receberam β-amiloid
An. Acad. Bras. Ciênc.. Publicado em: 11/07/2016
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8. Fluvoxamine alters the activity of energy metabolism enzymes in the brain
Objective: Several studies support the hypothesis that metabolism impairment is involved in the pathophysiology of depression and that some antidepressants act by modulating brain energy metabolism. Thus, we evaluated the activity of Krebs cycle enzymes, the mitochondrial respiratory chain, and creatine kinase in the brain of rats subjected to prolonged adm
Rev. Bras. Psiquiatr.. Publicado em: 17/03/2014
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9. Espectroscopia de fósforo por ressonância magnética em malformações do desenvolvimento cortical
IntroductionMalformations of cortical development (MCD) result from disruptions in the dynamic process of cerebral corticogenesis and are important causes of epilepsy, motor deficits and cognitive impairment.ObjectivesThe aim of this study was to evaluate phospholipids metabolism in vivo in a series of patients with epilepsy and MCD.MethodsThirty-seven patie
Arq. Neuro-Psiquiatr.. Publicado em: 2013-07
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10. Autorregulação encefálica durante manobra de preensão manual avaliada pela técnica de autorregressão de médias móveis através do Doppler transcraniano / Cerebral hemodynamic changes assessed by transcranial Doppler ultrasonography during handgrip maneuver
We investigated the effect of handgrip (HG) maneuver on time-varying estimates of dynamic cerebral autoregulation (CA), using the autoregressive moving average (ARMA) technique. Twelve healthy subjects were recruited to perform HG maneuver during 3 minutes with 30% of maximum contraction force. Cerebral blood flow velocity, end-tidal CO2 pressure (PETCO2), a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/08/2012
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11. Alterações metabólicas cerebrais associadas aos fatores de risco cardiovascular: um estudo de tomografia por emissão de pósitron (PET) / Abnormalities on brain metabolism associated to cardiovascular risk factors: a positron emission tomography (PET) study
INTRODUCTION: Cardiovascular risk factors (CVRF) are known to affect cerebral blood flow, possibly contributing to cognitive decline and to the emergence of Alzheimers disease (AD), the commonest form of dementia. Positron emission tomography (PET) with 18-fluoro-2-deoxyglucose (18FFDG) has been widely used to demonstrate specific patterns of reduced brain g
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/12/2011
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12. Reversibilidade parcial de alterações na função cerebral após perda de peso em humanos obesos / Partial reversibility of dysfunctional brain activity following weight loss in obese humans
A obesidade, definida como o acúmulo excessivo ou anormal de gordura que pode causar dano à saúde do indivíduo, é considerada atualmente um dos principais problemas de saúde pública. Ela resulta de um desequilíbrio entre a ingestão alimentar e o gasto de energia. O controle do balanço energético de animais e seres humanos é realizado pelo sistema
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/12/2011