Cervical Intraepithelial Neoplasia Cin
Mostrando 1-12 de 81 artigos, teses e dissertações.
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1. Methylation in the promoter regions of WT1, NKX6-1 and DBC1 genes in cervical cancer tissues of Uygur women in Xinjiang
Abstract This study aimed to explore: 1) DNA methylation in the promoter regions of Wilms tumor gene 1 (WT1), NK6 transcription factor related locus 1 gene (NKX6-1) and Deleted in bladder cancer 1 (DBC1) gene in cervical cancer tissues of Uygur women in Xinjiang, and 2) the correlation of gene methylation with the infection of HPV16/18 viruses. We detected H
Genet. Mol. Biol.. Publicado em: 2018-03
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2. Overexpression of ezrin and galectin-3 as predictors of poor prognosis of cervical cancer
The aim of this study was to explore the correlation of ezrin and galectin-3 expressions with prognosis in cervical cancer. The immunohistochemical method was applied to detect ezrin and galectin-3 expressions in normal cervix tissues (n=30), cervicitis tissues (n=28), cervical intraepithelial neoplasia (CIN) tissues (classified as I-III, n=89), and cervical
Braz J Med Biol Res. Publicado em: 23/03/2017
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3. CCR2 and CCR5 genes polymorphisms in women with cervical lesions from Pernambuco, Northeast Region of Brazil: a case-control study
Polymorphisms in chemokine receptors play an important role in the progression of cervical intraepithelial neoplasia (CIN) to cervical cancer (CC). Our study examined the association of CCR2-64I (rs1799864) andCCR5-Δ32 (rs333) polymorphisms with susceptibility to develop cervical lesion (CIN and CC) in a Brazilian population. The genotyping of 139 women wit
Mem. Inst. Oswaldo Cruz. Publicado em: 15/03/2016
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4. Association between cervical lesion grade and micronucleus frequency in the Papanicolaou test
The aim of this study was to evaluate the association between the frequency of micronuclei (MN) and the cellular changes detected in the conventional Papanicolaou test. One hundred and seventy-four Papanicolaou test smears with cellular changes were examined. MN screening was done in cytopathological smears by counting 1,000 cervical cells in a light microsc
Genet. Mol. Biol.. Publicado em: 2014-09
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5. Human papillomavirus infection among sexual partners attending a Sexually Transmitted Disease Clinic in Rio de Janeiro, Brazil
Cervical cancer is a major source of illness and death among women worldwide and genital infection with oncogenic human papillomavirus (HPV) its principal cause. There is evidence of the influence of the male factor in the development of cervical neoplasia. Nevertheless, the pathogenic processes of HPV in men are still poorly understood. It has been observed
Braz J Med Biol Res. Publicado em: 24/05/2013
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6. An evaluation of p16INK4a expression in cervical intraepithelial neoplasia specimens, including women with HIV-1
Although several studies have evaluated the role of p16INK4a as a diagnostic marker of cervical intraepithelial neoplasia (CIN) and its association with disease progression, studies regarding the role of p16INK4a in human immunodeficiency virus (HIV)-infected patients remain scarce. The present study was designed to determine the potential utility of p16INK4
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-08
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7. Prevalence and risk factors for cervical intraepithelial neoplasia among HIV-infected women
OBJECTIVES: To evaluate the prevalence and the risk factors for cervical intraepithelial neoplasia (CIN) among HIV-infected women. METHODS: Cross-sectional study of 494 HIV-infected women in Brazil, between 1998 and 2008. Gynecologic exam was performed, and samples were collected for cervical cytology and for HPV DNA detection. Cervical biopsy was carried ou
Brazilian Journal of Infectious Diseases. Publicado em: 2012-04
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8. Método para processamento e análise computacinal de imagens histopatológicas visando apoiar o diagnóstico de câncer de colo de útero / A Method for Processing and Computational Analysis of histopathological images to support the diagnosis of Cervical Cancer
A histopatologia é considerada um dos recursos diagnósticos mais importantes na prática médica e caracteriza-se pelo estudo das alterações estruturais e morfológicas das células e dos tecidos causadas por doenças. Atualmente, o principal método utilizado no diagnóstico histopatológico de imagens microscópicas, obtidas por meio de amostras em exa
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/11/2011
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9. High prevalence and low E6 genetic variability of human papillomavirus 58 in women with cervical cancer and precursor lesions in Southeast Mexico
Infection with some genotypes of human papillomavirus (HPV) is the most important risk factor associated with cervical cancer (CC). Throughout the world, HPV type 58 prevalence varies from one region to another; it is higher in women from certain countries in Asia and Latin America, such as China and Mexico. Although intratypic variants have been reported on
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-03
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10. Local lymphocytes and nitric oxide synthase in the uterine cervical stroma of patients with grade III cervical intraepithelial neoplasia
OBJECTIVES: Precancerous and cancerous cells can trigger an immune response that may limit tumor development and can be used as a prognostic marker. The aims of the present study were to quantify the presence of B and T lymphocytes, macrophages and cells expressing inducible nitric oxide synthase (iNOS) in the cervical stroma of women with grade III cervical
Clinics. Publicado em: 2010
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11. Nível de evidência acerca da eficácia das vacinas disponíveis contra a infecção pelo vírus HPV: revisão sistemática / Level of evidence about the efficacy of available vaccines against HPV infection: systematic review
Annually, about 500,000 new cases of cervical cancer occur and nearly 230,000 women die worldwide affected by this cancer, with particular emphasis on developing countries. Persistent HPV infection is a necessary condition for the occurrence of this disease and the oncogenic types HPV 16 and HPV 18 are responsible for approximately 70% of cervical cancer cas
Publicado em: 2010
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12. Expressão da p16INK4 em lesões precursoras de baixo grau do carcinoma escamoso do colo uterino : estudo prospectivo de seguimento
The squamous carcinoma of the cervix uterine is one of the neoplasias of bigger incidence in the whole world, also in Brazil, being responsible for the death of thousand of women to each year, great part of them occurring in full productive age. Throughout last the fifty years, diverse researchers have studied this neoplasia. We know that the invading phase
Publicado em: 2010