Chiral Amines
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. (+)-BINOL and Pure Shift Experiment: A Bidirectional Approach for NMR Chiral Discrimination of Overcrowded Spectra of Primary Amines
In this work, enantiopure 1,1’-bi-2-naphthol (BINOL) derivatives and carboxylic acids were evaluated as chiral solvating agents (CSAs) in the nuclear magnetic resonance (NMR) chiral discrimination of primary amines. Among the CSAs screened, the readily available (+)-BINOL revealed a simple and rapid chiral auxiliary for 1H NMR chiral discrimination. The pr
J. Braz. Chem. Soc.. Publicado em: 2018-08
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2. Reações de organocatálise com aminas quirais: aspectos mecanísticos e aplicações em síntese orgânica
The philosophy of organocatalysis is based on the utilization of organic compounds to catalyze organic transformations without the intervention of metals. This area has attracted much attention of the synthetic chemistry community on the last years, which can be confirmed by the explosion of published papers dealing with this subject. Phosphorus compounds, u
Química Nova. Publicado em: 2009
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3. Estudo da redução de iminas / Stydy of imine reduction
This project studies the behavior of a series of imines structurally analogues in bioreductions with baker yeast and carrots, and also with NaBH4 using alternative chiral reagents like 1-amine-2-propanol, prolinol and 2-a- hidroxybenzyl-benzimidazole or tartaric acid. For biocatalysis we investigated different temperatures, solvents and proportions of reagen
Publicado em: 2008
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4. A Interação substrato-modificador e sua importância para a hidrogenação enantiosseletiva de alfa-cetoésteres
The heterogeneous asymmetric catalysis plays an important and crucial role in many chemical processes and has therefore become a growing and interesting field. The enantioselective hydrogenation of α-ketoesters is one of the best known examples of such process. Methyl pyruvate, which can be converted to (R)- and (S)-methyl lactate with an enantioselecti
Publicado em: 2004
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5. Enantioselective synthesis of aziridines using asymmetric transfer hydrogenation as a precursor for chiral derivatives used as bonding agent for rocket solid propellants
A rapid, expedient and enantioselective method for the synthesis of beta-hydroxy amines and monosubstituted aziridines in up to 99% e.e., via asymmetric transfer hydrogenation of a-amino ketones and cyclisation through treatment with tosyl chloride and base, is described. (1R,2R)-N-(para-toluenesulfonyl)-1,2-ethylenediamine with formic acid has been utilised
Química Nova. Publicado em: 2002-11
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6. Catalytic asymmetric addition of diorganozinc reagents to N-phosphinoylalkylimines
The synthesis of α-chiral amines bearing two alkyl groups has been hampered by the accessibility and stability of the alkylimine precursor. Herein, we report an efficient strategy to generate the alkyl-substituted imine in situ that is compatible with the Me-DuPHOS monoxide·Cu(I) catalyzed addition of diorganozinc reagents. The sulfinic acid adduct of the
National Academy of Sciences.