Chirality
Mostrando 1-12 de 90 artigos, teses e dissertações.
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1. O uso do caso talidomida auxiliando na construção de significados em aulas de Química do Ensino Superior
Studies conducted in the field of education have, in many cases, highlighted the little insertion of teaching and learning theories in Natural Sciences classes, in Higher Education. We developed this study to analyze how Chemistry professors take ownership of a historical case to explain the concepts they develop in their classes. To do so, we analyzed this
Quím. Nova. Publicado em: 2020-04
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2. New Strategies in Enantioselective Hydrogenation on Supported Transition Metal Catalyst: Effects of Metal Sintering and Support Swelling
The effect of noble metal catalysts supported on an ionic exchange resin for the enantioselective hydrogenation of ethyl pyruvate to ethyl lactate was studied. High activity and moderate enantioselectivity levels were obtained. Pt was the best enantioselective metallic phase, followed by Pd and Au; Rh was the less enantioselective metallic phase. The effect
J. Braz. Chem. Soc.. Publicado em: 12/08/2019
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3. ELUCIDAÇÃO DA QUIRALIDADE INDUZIDA NA MOLÉCULA DANSILGLICINA NA COMPLEXAÇÃO COM A PROTEÍNA ALBUMINA DO SORO HUMANO (HSA)
Human serum albumin (HSA) plays an important role in the transport of a wide variety of substances, including compounds with pharmacological properties. The dansylglycine (DanG) is a fluorescent amino acid derivative specific for the site II of HSA. This work aimed to elucidate the induction of chirality in the DanG due to its bonding to the HSA. Theoretical
Quím. Nova. Publicado em: 2019-02
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4. Investigation of the Elastic Properties of Graphenylene Using Molecular Dynamics Simulations
Molecular dynamics simulations are used here to study the mechanical behavior of graphenylene under uni-directional and bi-directional loadings. The effects of nanosheet chirality and size on Young's modulus of graphenylene are investigated. Compared to graphene, graphenylene possess a smaller elastic modulus. It is shown that for large armchair and zigzag g
Mat. Res.. Publicado em: 16/11/2016
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5. CHROMATOGRAPHIC SEPARATION OF VERAPAMIL RACEMATE USING A VARICOL CONTINUOUS MULTICOLUMN PROCESS
Abstract Verapamil is a chiral drug that is marketed in its racemic form, but because of the pharmacological effects due to molecule’s chirality, one of the enantiomers is more potent, and the other exhibits different activities of therapeutic interest. The preparative separation of the verapamil enantiomers was performed using a continuous Varicol unit op
Braz. J. Chem. Eng.. Publicado em: 2015-12
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6. Resolução enantiomérica do secnidazol / Enantiomeric resolution of secnidazole
O secnidazol corresponde à formulação 1-(hidroxipropil)-2-metil-5-nitroimidazol e possui espectro de atividade contra microorganismos anaeróbicos e eficácia no tratamento de amebíase, giardíase, tricomoníase e vaginose bacteriana. Ele é comercializado na forma racêmica, isto é, na proporção 1:1 dos seus enantiômeros R e S. Não é oficial em ne
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/06/2012
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7. Perfis de espalhamento Raman ressonante em estruturas unidimensionais de carbono: cadeias lineares e nanotubos quiralmente enriquecidos
In resonant Raman scattering experiments using several laser lines, the intensity profile of the spectra as a function of the laser energy is related to the vibrational and electronic structure of the material. In this work, we have measured and interpreted the resonant Raman profiles for samples of chirality enriched single-walled carbon nanotube and for po
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/12/2011
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8. Composição e variabilidade enantiomérica de α-pineno em Constrictotermes cyphergaster (Silvestri, 1901) (Isoptera; Termitidae) / Composition and enantiomeric variability of α-pinene in Constrictotermes Cyphergaster (Silvestri, 1901) (Isoptera; Termitidae)
Termites are eusocial insects of isoptera order that part in seven families. In this study we analyze the chirality of α-pinene in the defensive secretion that C. cyphergaster (Isoptera, Termitidae, Nasutitermitinae) this compound showed that among the majority of termite volatile. Along with checking the chirality was made a study seeking to correlate
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/10/2011
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9. Composição e variabilidade enantiomérica de α-pineno em Constrictotermes cyphergaster (Silvestri, 1901) (Isoptera; Termitidae) / Composition and enantiomeric variability of α-pinene in Constrictotermes Cyphergaster (Silvestri, 1901) (Isoptera; Termitidae)
Termites are eusocial insects of isoptera order that part in seven families. In this study we analyze the chirality of α-pinene in the defensive secretion that C. cyphergaster (Isoptera, Termitidae, Nasutitermitinae) this compound showed that among the majority of termite volatile. Along with checking the chirality was made a study seeking to correlate
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/10/2011
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10. Separação enantiomérica do marcador molecular fmoc-poac em fase estacionária normal e reversa / Enantiomeric separation of fmoc-poac spin label by HPLC in normal and reverse stationary phase
A enantiosseparação de alguns compostos é um brilhante e interessante tópico de muitas áreas da química analítica, principalmente na farmacêutica e biomédica. Sabe-se que apesar dos enantiômeros apresentarem fórmulas e massa molecular iguais, quando expostos em um ambiente biológico podem mostrar grandes diferenças nas suas atividades biológica
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/09/2011
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11. Evolução biomolecular homoquiral: a origem e a amplificação da quiralidade nas moléculas da vida
The fact that biologically relevant molecules exist only as one of the two enantiomers is a fascinating example of complete symmetry breaking of chirality and has long intrigued our curiosity. The origin of this selective chirality has remained a fundamental enigma with regard to the origin of life since the time of Pasteur, 160 years ago. The symmetry break
Química Nova. Publicado em: 2010
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12. Caracterização e aplicação da fase estacionaria quiral tris(3,5-dimetilfenilcarbamato) de amilose na separação preparativa dos enantiomeros do omeprazol / Characterization and application of the amylose tris(3,5-dimethylphenylcarbamate) chiral stationary phase in omeprazole enantiomer preparative separation
O objetivo deste trabalho foi a síntese, em larga escala, da fase estacionária quiral tris(3,5-dimetilfenilcarbamato) de amilose e posterior investigação desta na separação preparativa dos enantiômeros do omeprazol por cromatografia líquida de alta eficiência. O carbamato de amilose, caracterizado por análise elementar e espectroscopia na região d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/07/2009