Chlorin
Mostrando 1-12 de 28 artigos, teses e dissertações.
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1. Avaliação do efeito vascular da terapia fotodinâmica empregando derivados de porfirina e clorina na membrana corioalantóica / Evaluation of vascular effect of photodynamic therapy using porphiryn and chlorin derivates in the chorioallantoic membrane
A Terapia Fotodinâmica (do inglês, Photodynamic Therapy - PDT) é uma técnica indicada para o tratamento local de câncer que vem tendo grandes avanços ao longo dos anos. A PDT consiste na interação entre luz e uma substância fotossensibilizadora, resultando na transformação do oxigênio molecular em oxigênio singleto, altamente reativo e tóxico p
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/02/2012
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2. Estudio fitoquímico de hojas de Uncaria guianensis y evaluación de actividad antibacteriana
A chlorin compound, pheophorbide a ethyl ester and a mixture of sterols known as β-sitosterol and stigmasterol, were isolated from the petroleum ether extract of Uncaria guianensis (Rubiaceae) leaves. Their structures were elucidated by detailed analysis of NMR spectra, including bidimensional techniques and by comparison with literature data. The antibacte
Acta Amazonica. Publicado em: 2011
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3. Comparative study of hydrocarbon oxygenation with ironchlorins and ironporphyrins as catalysts in homogeneous and heterogeneizated systems / Estudo comparativo da oxigenação de hidrocarbonetos com ferroclorinas e ferroporfirinas como catalisadores em meio homogêneo e heterogeneizados
In this work, the cyclohexane oxidation and the (Z)-cyclooctene epoxidation with iodosylbenzene (PhIO) e H2O2 as oxidants were studied. A comparison between fluorinated FeIIIchlorins and FeIIIporphyrins, [Fe(TFPCMG)]Cl, [Fe(TFPCMGCH3)]Cl2, [Fe(TFPP)]Cl, [Fe(TF4TMAPP)](CF3SO3)5 as catalysts was made either in solution or supported in silica matrices via eletr
Publicado em: 2008
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4. "Fotodegradação do Photodithazine e citotoxicidade dos fotoprodutos formados após irradiação com laser" / "Photobleaching of Photodithazine and cytotoxicity of photoproduct formation during illumination with laser"
A Terapia Fotodinâmica consiste em uma nova e promissora técnica de diagnóstico e tratamento de tumores malignos. O tratamento se baseia na administração intravenosa de um fotossensibilizador que acumula-se seletivamente em tecido tumoral, sendo a seguir excitado com luz visível gerando espécies tóxicas às células levando-as à morte. Neste trabalh
Publicado em: 2006
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5. A novel chlorin derivative of Meso-tris(pentafluorophenyl)-4-pyridylporphyrin: synthesis, photophysics and photochemical properties
A terapia fotodinâmica (TFD) está baseada na administração e no acúmulo de fotossensibilizador, por exemplo, de tipo porfirina ou clorina, em tecidos doentes. As clorinas apresentam propriedades fotofísicas semelhantes àquelas das porfirinas, mas com intensificação e deslocamento das bandas Q, o que faz com que sejam bons candidatos para TFD. Neste
Journal of the Brazilian Chemical Society. Publicado em: 2004-12
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6. Terapia fotodinâmica: aspectos farmacológicos, aplicações e avanços recentes no desenvolvimento de medicamentos
Photodynamic Therapy (PDT) is a clinical procedure, which utilize a photosensitive compound and light. This is a new modality of treatment for cancer, aged related macular degenerescence (AMD), psoriasis, arthritis, arterial restenosis, etc which exhibits efficiency, less traumatic effects, low recovery time and few co-lateral effects. The first officially a
Química Nova. Publicado em: 2002-09
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7. Antibody-targeted photolysis: selective photodestruction of human T-cell leukemia cells using monoclonal antibody-chlorin e6 conjugates.
Selective in vitro photodestruction of HPB-ALL human T-cell leukemia cells was accomplished using the photosensitizer chlorin e6 coupled through dextran molecules to an anti-T-cell monoclonal antibody (mAb), anti-Leu-1. Conjugates with mAb/chlorin molar ratios as high as 1:36 retained mAb binding activity, and the absorption spectrum and quantum efficiency f
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8. Protein engineering of cytochrome b562 for quinone binding and light-induced electron transfer
The central photochemical reaction in photosystem II of green algae and plants and the reaction center of some photosynthetic bacteria involves a one-electron transfer from a light-activated chlorin complex to a bound quinone molecule. Through protein engineering, we have been able to modify a protein to mimic this reaction. A unique quinone-binding site was
National Academy of Sciences.
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9. Tunichlorin: a nickel chlorin isolated from the Caribbean tunicate Trididemnum solidum.
Tunichlorin, a blue-green pigment isolated from the Caribbean tunicate Trididemnum solidum, has been identified as nickel(II) 2-devinyl-2-hydroxymethylpyropheophorbide a by chemical and spectroscopic methods, with confirmation by partial synthesis of dimethyl tunichlorin from chlorophyll a. Nickel chlorins have been reported from geological sources but not f
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10. Photoactive Porphyrin Derivative with Broad-Spectrum Activity against Oral Pathogens In Vitro
Photodynamic therapy (PDT) has historically been used as a means to treat cancerous tumors but has recently been used to kill bacterial cells through the use of targeted photosensitizers. PDT is a potential adjunct to scaling and root planing in the treatment of periodontal disease. However, the effectiveness of porphyrin derivatives against microorganisms h
American Society for Microbiology.
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11. Three-dimensional structure of cyanomet-sulfmyoglobin C.
The atomic structure of horse heart cyanomet-sulfmyoglobin C has been established by x-ray crystallographic techniques to a resolution of 2.0 A with an R value of 0.129. The protoheme IX prosthetic group of this thermodynamically stable sulfmyoglobin derivative has been converted to a chlorin in which the pyrrole ring bearing the 4-vinyl group is saturated a
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12. Antibody-targeted photolysis: in vitro studies with Sn(IV) chlorin e6 covalently bound to monoclonal antibodies using a modified dextran carrier.
A monoclonal antibody-dextran-Sn(IV) chlorin e6 immunoconjugate was prepared by a technique involving the site-specific covalent modification of the monoclonal antibody oligosaccharide moiety. Dextran carriers were synthesized with a single chain-terminal hydrazide group, which was used as the coupling point between the carrier and the monoclonal antibody ca