Cholera Toxin
Mostrando 1-12 de 1015 artigos, teses e dissertações.
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1. Parenteral adjuvant potential of recombinant B subunit of Escherichia coli heat-labile enterotoxin
BACKGROUND The B subunit of Escherichia coli heat-labile enterotoxin (LTB) is a potent mucosal immune adjuvant. However, there is little information about LTB's potential as a parenteral adjuvant. OBJECTIVES We aimed at evaluating and better understanding rLTB's potential as a parenteral adjuvant using the fused R1 repeat of Mycoplasma hyopneumoniae P97 ad
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-12
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2. From Escherichia coli heat-stable enterotoxin to mammalian endogenous guanylin hormones
The isolation of heat-stable enterotoxin (STa) from Escherichia coli and cholera toxin from Vibrio cholerae has increased our knowledge of specific mechanisms of action that could be used as pharmacological tools to understand the guanylyl cyclase-C and the adenylyl cyclase enzymatic systems. These discoveries have also been instrumental in increasing our un
Braz J Med Biol Res. Publicado em: 03/03/2014
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3. Papel dos canais K+ATP na resposta eletrofisiológica ao FSH e ao isoproterenol em células de Sertoli
Follicle-stimulating hormone (FSH) produces a dual effect on the membrane potential of Sertoli cells, with an initial rapid phase, which comprises a hyperpolarization for a period of seconds and a depolarization phase, wich occurs more slowly, within minutes. The depolarization phase involves calcium entry stimulated by FSH. Isoproterenol, an agonist of ¿-a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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4. Centros subcorticais dos sistemas visual primário e óptico acessório no mocó (kerodon rupestris): caracterização pela projeção retiniana e citoarquitetura.
The primary and accessory optic systems comprise two set of retinorecipient neural clusters. In this study, these visual related centers in the rock cavy were evaluated by using the retinal innervations pattern and Nissl staining cytoarchigtecture. After unilateral intraocular injection of cholera toxin B subunit and immunohistochemical reaction of coronal a
Publicado em: 2009
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5. Development and characterization of an anti-schistosomiasis vaccine composed by the Sm14 protein, from Schistosoma mansoni, using the B subunit of cholera toxin (CTB) as adjuvant / Desenvolvimento e caracterização de uma vacina antiesquistossomose composta pela proteína Sm14 de Schistosoma mansoni utilizando a subunidade B da toxina colérica (CTB) com adjuvante
Introdução: o desenvolvimento de uma vacina contra a esquistossomose será um importante avanço no controle desta doença crônica e muitas vezes debilitante, afetando milhões de pessoas em todo o mundo. Neste trabalho, descrevemos o uso da subunidade B da toxina colérica (CTB) geneticamente fusionada com Sm14 - uma proteína ligadora de ácidos graxos
Publicado em: 2009
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6. CaracterizaÃÃo molecular de cepas de Vibrio cholerae O26, isoladas de processos entÃricos humanos no nordeste do Brasil
The emergence of the Vibrio cholerae O139 serogroup as a second ethiologic agent for cholera served as an alert to the rise of other epidemic strains that may pass unnoticed by traditional methods of diagnosis, usually based on the use of antiserum directed against the traditional O1 serogroup. In previous studies, out of 179 non-O1/ non-O139 V. cholerae str
Publicado em: 2008
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7. Cytoarchitectural and immunohistochemical analysis of the visual system of tuffed capuchin (Cebus apella). / Análise citoarquitetônica e imunoistoquímica de estruturas do sistema visual de macacos-prego (Cebus apella)
O estudo do sistema visual de macacos-prego representa importante questão devido ao aspecto evolutivo que a espécie apresenta. Foram utilizados cinco macacos-prego, 2 kg. Foi efetuda injeção intra-ocular de 100 ml de solução aquosa de toxina colérica subunidade B (CTb) a 1%, sendo a perfusão realizada 15 dias após a injeção int
Publicado em: 2008
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8. A Zona Incerta no sagüi (Callithrix jacchus): Análise Citoarquitetônica, Neuroquímica e Projeção Retiniana
The retinal projections in mammals usually reach, classically, three major functional systems: the primary visual system, the accessory optic system, and the circadian timing system. But the retinal projections also reach areas classically considered non-visual, one of which groups the neurons of the zona incerta (ZI), target this study. The primary visual s
Publicado em: 2008
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9. Transferrin uptake may occur through detergent-resistant membrane domains at the cytopharynx of Trypanosoma cruzi epimastigote forms
Uptake of transferrin by epimastigote forms of the protozoan Trypanosoma cruzi occurs mainly through a cytostome/ cytopharynx, via uncoated endocytic vesicles that bud off from the bottom of the cytopharynx. We have here examined whether detergent-resistant membrane (DRM) domains might be involved in this process. Purified whole cell membrane fractions were
Memórias do Instituto Oswaldo Cruz. Publicado em: 30/10/2007
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10. Adjuvant requirement for successful immunization with recombinant derivatives of Plasmodium vivax merozoite surface protein-1 delivered via the intranasal route
Recently, we generated two bacterial recombinant proteins expressing 89 amino acids of the C-terminal domain of the Plasmodium vivax merozoite surface protein-1 and the hexa-histidine tag (His6MSP1(19)). One of these recombinant proteins contained also the amino acid sequence of the universal pan allelic T-cell epitope (His6MSP1(19)-PADRE). In the present st
Memórias do Instituto Oswaldo Cruz. Publicado em: 10/05/2007
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11. "O núcleo supraquiasmático e o folheto intergeniculado do mocó (Kerodon rupestris): Projeções retinianas e caracterização imuno-histoquímica
In this study, two circadian related centres, the suprachiasmatic nucleus (SCN) and the intergeniculate leaflet (IGL) were evaluated in respect to their cytoarchitecture, retinal afferents and chemical content of major cells and axon terminals with a tract tracer and immunohistochemical techniques in the rock cavy (Kerodon rupestris), a Brazilian caviidae ro
Publicado em: 2007
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12. Adenosine A1 receptor-mediated inhibition of in vitro prolactin secretion from the rat anterior pituitary
In previous studies, we demonstrated biphasic purinergic effects on prolactin (PRL) secretion stimulated by an adenosine A2 agonist. In the present study, we investigated the role of the activation of adenosine A1 receptors by (R)-N6-(2-phenylisopropyl)adenosine (R-PIA) at the pituitary level in in vitro PRL secretion. Hemipituitaries (one per cuvette in fiv
Brazilian Journal of Medical and Biological Research. Publicado em: 22/09/2006