Chromatin Condensation
Mostrando 1-12 de 240 artigos, teses e dissertações.
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1. Use of the ACP® and BTS extenders for cooling at 15°C white-lipped peccary (Tayassu pecari) semen
RESUMO: Para auxiliar na conservação da espécie e permitir o uso racional do queixada em cativeiro é de grande importância o conhecimento sobre a reprodução da espécie. Objetivou-se avaliar o efeito dos diluidores de sêmen ACP-103®, ACP-116® e BTS na viabilidade espermática durante a refrigeração do sêmen do Tayassu pecari. Foram refrigerados
Pesq. Vet. Bras.. Publicado em: 01/07/2019
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2. Antineoplastic potential of the aqueous crude extract of Eugenia uniflora L. in human cervical cancer
Abstract Considering the high prevalence of human cervical cancer and the adverse effects of the available treatments, it is important to develop studies involving plants. Eugenia uniflora L. is a Brazilian native plant widely used in folk medicine and some biological effects have already been described. In this study, we investigated the biologicals effects
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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3. Heterochromatin distribution and histone modification patterns of H4K5 acetylation and H3S10 phosphorylation in Capsicum L.
Abstract We evaluated domesticated Capsicum pepper species from Brazil using classical and molecular cytogenetic techniques, and describe here for the first time their immunostaining patterns using anti-H4K5ac and anti-H3S10ph antibodies. All accessions showed 2n = 24 chromosomes with metacentric and submetacentric morphologies. CMA3 patterns ranged from fou
Crop Breed. Appl. Biotechnol.. Publicado em: 2018-04
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4. Tissue apoptosis in mice infected with
Leptospira interrogans serovar IcterohaemorrhagiaeAbstract Background: This investigation aimed to evaluate the occurrence of some apoptotic features induced by
Leptospira interrogans serovar Icterohaemorrhagiae infection in young BALB/c mice during 2, 4, 7, 10, 14 and 21 days post-infection (dpi).Methods: The animals were
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/08/2015
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5. Simultaneous Administration of Dexamethasone and Vitamin E Reversed Experimental Varicocele-induced Impact in testicular tissue in Rats; Correlation with Hsp70-2 Chaperone Expression
ABSTRACTPurpose:This study aimed to investigate the protective effects of isolated and co-administration of vitamin E (VitE) and dexamethasone (DEX) on varicocele (VCL)-induced damages in testicular tissue.Materials and Methods:Wistar rats were divided into five groups (n=6), including; control-sham, non-treated VCL-induced, VitE-treated VCL-induced (VitE, 1
Int. braz j urol.. Publicado em: 2015-08
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6. Resistance of cervical adenocarcinoma cells (HeLa) to venom from the scorpion Centruroides limpidus limpidus
Background : The venom of Centruroides limpidus limpidus (Cll) is a mixture of pharmacologically active principles. The most important of these are toxic proteins that interact both selectively and specifically with different cellular targets such as ion channels. Recently, anticancer properties of the venom from other scorpion species have been described.
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 02/09/2013
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7. A phthalide derivative isolated from endophytic fungiPestalotiopsis photiniae induces G1 cell cycle arrest and apoptosis in human HeLa cells
MP [4-(3′,3′-dimethylallyloxy)-5-methyl-6-methoxyphthalide] was obtained from liquid culture of Pestalotiopsis photiniaeisolated from the Chinese Podocarpaceae plant Podocarpus macrophyllus. MP significantly inhibited the proliferation of HeLa tumor cell lines. After treatment with MP, characteristic apoptotic features such as DNA fragmentation and chrom
Braz J Med Biol Res. Publicado em: 30/07/2013
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8. Effects of Epstein-Barr virus on the development of dendritic cells derived from cord blood monocytes: an essential role for apoptosis
OBJECTIVE: Epstein-Barr virus (EBV) is a ubiquitous human γ-herpes virus, which can adapt and evade host immune defense. Dendritic cells (DCs) play a pivotal role in the initiation and maintenance of immune responses. This study investigated the effects of EBV on cord blood monocytes derived DCs (CBDC). METHODS: Monocytes were isolated from cord blood and c
Brazilian Journal of Infectious Diseases. Publicado em: 2012-02
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9. Antitumorigenicity of xanthones-rich extract from Garcinia mangostana fruit rinds on HCT 116 human colorectal carcinoma cells
This study aimed to investigate the antitumorigenicity of xanthones-rich extract from Garcinia mangostana L., Clusiaceae, fruit rinds which was obtained by a simple recrystallization of 75% ethanolic extract. α-Mangostin content of the extract was determined qualitatively by TLC and quantitatively by HPLC, and total xanthones content was quantified by UV sp
Revista Brasileira de Farmacognosia. Publicado em: 09/09/2011
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10. Análise morfológica das espermátides e dos espermatozóides de Chrysomya megacephala (Fabricius) (Diptera: Calliphoridae) nos tratos reprodutores
Diptera constitutes one of the four largest orders of insects. The Oriental latrine-fly Chrysomya megacephala (Fabricius) belongs to the family Calliphoridae and is associated with medic, veterinary, sanitary and forensic issues. The aim of this research was to characterize the utrastructural aspects of the spermiogenesis and spermatozoa of the C. megacephal
Publicado em: 2008
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11. Estudo da expressão dos genes de classe I das histonas desacetilases (HDACs 1,2,3 e 8) em Leucemia Linfóide Aguda de crianças e adolescentes / Class 1 Histone Deacetylases Gene Expression in Childhood Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia (ALL) is a heterogeneous disease with distinct biologic and prognostic groups. In addition to genetic alterations, epigenetic processes play an important role in carcinogenesis, among which histone acetylation/deacetylation is crucial for chromatin modulation structure and transcriptional activity. Histone acetylation is regulate
Publicado em: 2008
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12. Caracterização da atividade antitumoral das tiossemicarbazonas derivadas de N(4)-Metil-Toluil-2-acetilpiridina e de 2-piridinoformamida e seus complexos metálicos: avaliação do potencial radiofarmaceutico / CHARACTERIZATION OF THE ANTITUMURAL ACTIVITY OF THE THIOSEMICARBAZONES DERIVED FROM N(4)-METHYL-TOLYL-2- ACETYLPYRIDINE AND 2-PIRIDINOFORMAMIDE AND ITS METAL COMPLEX: EVALUATION OF THE RADIOPHARMACEUTICAL POTENTIAL.
Thiosemicarbazones have attracted great pharmacological interest because of their biological properties, such as cytotoxic activity against multiple strains of human tumors. The most studied compounds are pyridine-based because of their resemblance to pyridoxal metabolites that attach to co-enzyme B6-dependant enzymes. This work aimed the characterization of
Publicado em: 2008