Chromosome Alterations
Mostrando 1-12 de 298 artigos, teses e dissertações.
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1. EFEITOS DA CANOAGEM NAS HABILIDADES MOTORAS DE CRIANÇAS E ADOLESCENTES COM SÍNDROME DE DOWN
RESUMO Introduction Down syndrome (DS) is a genetic condition characterized by an inadequate numerical distribution in chromosome pairing, with extra genetic material related to pair 21 leading to alterations that affect the development of several motor components. Objective To analyze the effects of kayak training for eight weeks on the gross motor skills
Rev Bras Med Esporte. Publicado em: 2020-08
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2. Analysis of filaggrin 2 gene polymorphisms in patients with atopic dermatitis,
Abstract Background: Polymorphisms of the filaggrin 2 gene (rs 12568784 and rs 16899374) are associated with persistent atopic dermatitis in African American patients. Filaggrin 2 is a protein with a function similar to filaggrin and also encoded in the epidermal differentiation complex on chromosome 1q21. Objective: To evaluate the polymorphisms in the fi
An. Bras. Dermatol.. Publicado em: 2020-03
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3. Investigation of chromosomal alterations in patients with Alzheimer's disease in the state of Amazonas, Brazil
RESUMO Doença de Alzheimer (DA) tem como principal característica a deterioração das funções cerebrais. Quanto a sua etiologia ainda é complexa e indefinida, apesar do progresso alcançado na compreensão de seus mecanismos neurológicos, infecciosos, bioquímicos, genéticos e citogenéticos. Considerando isto, nós investigamos a presença de altera
Arq. Neuro-Psiquiatr.. Publicado em: 10/01/2020
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4. Two independent grain-length mutants mapped to a single region on the long arm of chromosome 2 in rice
ABSTRACT Grain shape in rice is a key determinant of grain appearance, yield and market value, and thus has been widely studied. Rice mutant lines with long-grain phenotypes were previously isolated from an M2 population derived from mutagenized mature pollen grains that were treated with gamma-ray irradiation for a cultivar Ma85. To understand the genetic b
Bragantia. Publicado em: 02/08/2018
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5. Genotoxic potential of the latex from cotton-leaf physicnut (Jatropha gossypiifolia L.)
Jatropha gossypiifolia L. (Euphorbiaceae), popularly known as cotton-leaf physicnut, is a milky shrub notable for its medicinal properties. The present study aimed to evaluate the toxic, cytotoxic and genotoxic effects of the latex of J. gossypiifolia, using Allium cepa L. as test system. Seeds of A. cepa were exposed to five concentrations of the latex (1.2
Genet. Mol. Biol.. Publicado em: 2015-03
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6. The investigation of cytogenetic and oxidative effects of diffractaic acid on human lymphocyte cultures
Diffractaic acid (DA) is a naturally occurring depside derivative found in several lichen species. It has a wide range of important biological effects such as analgesic and antiviral properties, although its cytotoxic, cytogenetic and oxidative effects have not been investigated in human blood tissue yet. Therefore, increasing concentrations (1, 5, 10, 25, 5
Braz. arch. biol. technol.. Publicado em: 2015-02
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7. Cytogenetic characterization of F1, F2 and backcross hybrids of the Neotropical catfish species Pseudoplatystoma corruscans and Pseudoplatystoma reticulatum (Pimelodidae, Siluriformes)
The cytogenetic characteristics of Pseudoplatystoma corruscans and Pseudoplatystoma reticulatum and their F1, F2 and backcross hybrids were assessed by using chromosome banding techniques. The diploid number of 56 chromosomes was constant in all species and lineages, with a karyotypic formula containing 20 metacentric, 12 submetacentric, 12 subtelocentric an
Genetics and Molecular Biology. Publicado em: 02/02/2012
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8. Philadelphia-negative chronic myeloproliferative neoplasms
Chronic myeloproliferative diseases without the Philadelphia chromosome marker (Ph-), although first described 60 years ago, only became the subject of interest after the turn of the millennium. In 2001, the World Health Organization (WHO) defined the classification of this group of diseases and in 2008 they were renamed myeloproliferative neoplasms based on
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2012
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9. Investigação de alterações na região 22q11 em indivíduos com fissura de palato / Investigation of the alterations in the region 22q11 in individuals with cleft palate
Purpose: To investigate alterations (deletions/duplications) in the 22q11 region in individuals with cleft palate aged 0-2 years, in order to perform early diagnosis of 22q11 deletion syndrome (SD22q11). Local: Genetics and Human Cytogenetics Laboratory, HRAC/USP, Bauru-SP. Methods: We selected 55 individuals with cleft palate, both genders, registered and i
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/12/2011
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10. AvaliaÃÃo dos genes MLL, RB e TP53 em pacientes com sÃndrome mielodisplÃsica / Evaluation of genes MLL, RB and TP53 in patients with Myelodysplastic Syndromes
Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal disorders affecting the hematopoietic pluripotent cell, characterized by low cell counts in peripheral blood, dysplasia in one or more cell lines, inefficient hematopoiesis and increased risk of progression to acute myeloid leukemia. Although the disease can affect patients of other ag
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/06/2011
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11. Alterações sistêmicas e comportamentais de interesse odontológico em pacientes com síndrome de Down / Dental implications of systemic and behavior alterations in Downs syndrome patients
Downs syndrome (DS) is the most common genetic disorder and it is caused by the trissomy of 21 chromosome. It is characterized by mental retardation, physical alterations and several systemic co morbidities. The aim of this study was to evaluate behavior and systemic alterations with dental implications in DS patients and discuss the dental management of the
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2011
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12. Cytogenetic effect of 5-azacytidine in patients with hematological malignancies
BACKGROUND: Recently, the importance of cytogenetics has grown in the diagnosis, prognosis and treatment of leukemias and myelodysplastic syndromes. 5-azacytidine is a drug that has well-known cytogenetical effects and is approved in the treatment of myelodysplastic syndromes. To date, no studies have been performed to evaluate the impact of 5-azacytidine on
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2011-10