Ciclocondensation
Mostrando 1-2 de 2 artigos, teses e dissertações.
-
1. Acilenaminonas: Síntese e Aplicação na Obtenção de Pirazóis, Pirazolo[3,4-d]piridazinonas e Pirazolo[1,5-a]pirimidinas / Acylenaminones: Synthesis and Application in the Obtaining of Pyrazoles, Pyrazolo[3,4-d]pyridazinones and Pyrazolo[1,5-a]pyrimidines
The regioespecific synthesis of a series of 14 N-acylated enaminones (52-88%) from the acylation reaction of secondary -enamino ketones [RC(O)CH=CHNR1R2; R = Ph, 4- FC6H4, 4-NO2C6H4, thien-2-yl, CCl3, CF3; R1 = H; R2 = Bn, Ph, 4-NO2C6H4] with trifluoroacetic anhydride or ethyl oxalyl chloride in pyridine is reported. On the other hand, when tertiary enaminon
Publicado em: 2009
-
2. Reações de 1,1,1-tricloro-4-metoxi-3-penten-2-ona com hidrazinas monosubstituídas / 1,1,1-trichloro-4-methoxy-3-penten-2-ona reaction with hydrazines
The 1,1,1-trichloro-4-methoxy-3-penten-2-ona (CCl3COCH=CHOMe) reaction with hydrazines series (RNHNH2, where R = H, Me, tert-Bu, Ph, Ph(F)5, Ph-4-NO2, CO2Me e CONH2) yield to the pyrazoles N-substituted and derivatives formation by [3 + 2] ciclocondensations reactions. These compounds formation is regioespecific, it means, termodinamically controled (excepti
Publicado em: 2005