Cis Regulatory
Mostrando 1-12 de 1355 artigos, teses e dissertações.
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1. Comparative Analysis of C-repeat Binding Factors (CBFs) in Tomato and Arabidopsis
Abstract Cold stress is one of the limiting factors of plant production that plants use different mechanisms for cold tolerance. CBF genes play critical role to regulate the cold responsive genes. To better understand of CBF gene functions, the tomato-CBFs and Arabidopsis-CBFs were evaluated using bioinformatics tools, and finally the expression patterns of
Braz. arch. biol. technol.. Publicado em: 29/08/2019
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2. COX-2 gene expression and methylation profile in Sapajus apella as an experimental model for gastric adenocarcinoma
Abstract Gastric cancer (GC) remains one of the main causes of cancer-related death worldwide. There are two distinct histological types of GC: diffuse and intestinal. The latter is characterized by the presence of pre-neoplastic lesions. One of the most frequently altered enzymes in intestinal GC is COX-2, an important lesion marker. This work aimed to stud
Genet. Mol. Biol.. Publicado em: 14/05/2018
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3. Molecular evolution of HoxA13 and the multiple origins of limbless morphologies in amphibians and reptiles
Developmental processes and their results, morphological characters, are inherited through transmission of genes regulating development. While there is ample evidence that cis-regulatory elements tend to be modular, with sequence segments dedicated to different roles, the situation for proteins is less clear, being particularly complex for transcription fact
Genet. Mol. Biol.. Publicado em: 2015-09
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4. Ethylene response factors gene regulation and expression profiles under different stresses in rice
Stresses can cause large yield reductions in cultivated plants. The response to these stresses occurs via a plethora of signalling pathways, where a large number of genes is induced or repressed. Among the environmental stress responsive genes, there are the members of the ethylene response factors (ERF) gene family. The mRNA levels of different ERF are regu
Theor. Exp. Plant Physiol.. Publicado em: 2013-12
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5. Indução do promotor GmNAC6 por elicitores de estresses e mapeamento de regiões reguladoras / Induction of the promoter GmNAC6 by elicitors of stress and mapping of regulatory regions
NAC domain-containing proteins are unique to plants and comprise a large gene family of transcriptional factors implicated in diverse aspects of plant development and stress responses. The GmNAC6 was recently identified as a downstream component of the ER (endoplasmic reticulum) stress- and osmotic stress-induced NRP (N-rich proteins)-mediated cell death sig
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2012
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6. Essential regulatory elements for NHE3 gene transcription in renal proximal tubule cells
The objectives of the present study were to identify the cis-elements of the promoter absolutely required for the efficient rat NHE3 gene transcription and to locate positive and negative regulatory elements in the 5’-flanking sequence (5’FS), which might modulate the gene expression in proximal tubules, and to compare this result to those reported for i
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-06
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7. Regulatory elements involved in the post-transcriptional control of stage-specific gene expression in Trypanosoma cruzi: a review
Trypanosoma cruzi, a protozoan parasite that causes Chagas disease, exhibits unique mechanisms for gene expression such as constitutive polycistronic transcription of protein-coding genes, RNA editing and trans-splicing. In the absence of mechanism controlling transcription initiation, organized subsets of T. cruzi genes must be post-transcriptionally co-reg
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-05
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8. Transcriptional activity of the 5'-flanking region of the thyroid transcription factor-1 gene in human thyroid cell lines
Thyroid transcription factor-1 (TTF-1, NKX2-1) is a homeodomain-containing transcriptional factor that binds to and activates the promoters of thyroid and lung-specific genes, such as thyroglobulin, thyroid peroxidase, and thyroid stimulating hormone receptor. TTF-1 is known to play a key role in the development of the thyroid. However, the precise mechanism
Genetics and Molecular Biology. Publicado em: 03/12/2010
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9. Cloning, mapping and molecular characterization of porcine progesterone receptor membrane component 2 (PGRMC2) gene
Progesterone plays an important role in sow reproduction by stimulating classic genomic pathways via nuclear receptors and non-genomic pathways via membrane receptors such a progesterone receptor membrane component 2 (PGRMC2). In this work, we used radiation hybrid mapping to assign PGRMC2 to pig chromosome 8 and observed that this receptor has two transcrip
Genetics and Molecular Biology. Publicado em: 25/06/2010
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10. Novel sequence variations in LAMA2 and SGCG genes modulating cis-acting regulatory elements and RNA secondary structure
In this study, we detected new sequence variations in LAMA2 and SGCG genes in 5 ethnic populations, and analysed their effect on enhancer composition and mRNA structure. PCR amplification and DNA sequencing were performed and followed by bioinformatics analyses using ESEfinder as well as MFOLD software. We found 3 novel sequence variations in the LAMA2 (c.31
Genetics and Molecular Biology. Publicado em: 29/01/2010
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11. Identificação de mecanismos reguladores RALDH2 durante a padronização dorso-ventral da medula espinhal. / Identification of RALDH2 regulatory mechanisms during the spinal cord dorsal-ventral patterning.
A sinalização pelo ácido retinóico (AR) é fundamental para o correto desenvolvimento embrionário. A principal enzima responsável pela síntese do AR durante o desenvolvimento é a Raldh2 (Aldh1a2), cujo padrão de expressão é bastante dinâmico. Apesar dos padrões de expressão da raldh2 e seus papéis durante o desenvolvimento já estarem bem esta
Publicado em: 2010
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12. Cloning of high molecular weight gluten subunit promoter and study on its function in wheat
The aim of this work was to study the cloning and characterization of HMW-GS 1Dx2 promoter from Triticum aestivum. A 1050 bp partial promoter fragment including a putative TATA box and 5' encoding sequence of the gene was cloned by amplifying the upstream sequences using the nest-PCR with appropriate primers. The analysis of the promoter sequence against the
Brazilian Archives of Biology and Technology. Publicado em: 2009-04