Citotoxic Activity
Mostrando 1-12 de 27 artigos, teses e dissertações.
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1. Atividade antimicrobiana e citotoxicidade in vitro do óleo essencial de Tagetes minuta L. visando à aplicação no controle da mastite bovina
RESUMO O objetivo deste estudo foi avaliar a atividade antimicrobiana in vitro do óleo essencial de Tagetes minuta L. contra Staphylococcus aureus e Escherichia coli e a citotoxicidade sobre células epiteliais da glândula mamária bovina (MAC-T), visando a seu uso no tratamento da mastite bovina. A análise qualitativa do óleo revelou cis-tagetona (24,24
Arq. Bras. Med. Vet. Zootec.. Publicado em: 10/10/2019
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2. PHENOLIC DERIVATIVES AND ANTIOXIDANT ACTIVITY OF POLAR EXTRACTS FROM Bauhinia pulchella
A tea made with the leaves or stem bark of Bauhinia pulchella Benth (Fabaceae) is used in the treatment of diabetes. Ethanol (EEF) and aqueous (EAF) extracts were obtained from the leaves and the antioxidant and citotoxic activities were tested, as well as quantify the content of flavonoids and phenolic compounds (TPC). EEF and EAF showed similar profiles by
Quím. Nova. Publicado em: 2018-04
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3. Investigação da reação de Morita-Baylis-Hillman em reator de micro-ondas usando aldeídos aromáticos e isatina como eletrófilos: avaliação da atividade citotóxica em linhagem de células de leucemia promielocítica humanas (HL-60). / Investigation of Morita-Baylis-Hillman Reaction on Microwave Reactor using Aromatic Aldehydes and Isatin as Eletrophiles: Evaluation of Cytotoxic Activity in cell line human promyelocytic leukemia (HL-60).
In this work, we describe the investigation of the Morita-Baylis-Hillman reaction in microwave reactor, under closed vessel conditions to prepare 40 adducts, six novel, using 30 aromatic aldehydes and isatin as electrophiles and acrylonitrile (62a) , methyl acrylate (2), hydroxyethyl acrylate (62b), 2,2-dimethyl-1 ,3-dioxalyl acrylate (62c) and 2,3-dihydroxy
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/11/2012
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4. Citotoxic activity evaluation of essential oils and nanoemulsions of Drimys angustifolia and D. brasiliensis on human glioblastoma (U-138 MG) and human bladder carcinoma (T24) cell lines in vitro
The species Drimys angustifolia Miers and D. brasiliensis Miers, commonly known as "casca-de-anta", have in their leaves essential oils that can confer cytotoxic effects. In this study, we evaluated the citotoxic effects of the volatile oils from these two species. We also proposed a nanoemulsion formulation for each of the species and assessed the in vitro
Rev. bras. farmacogn.. Publicado em: 22/11/2012
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5. Produção, isolamento e identificação de metabólito com atividade citotóxica de cultura de Streptomyces carpaticus / Production, isolation and identification of citotoxic activity metabolite of streptomyces carpaticus culture
This study addresses the production, isolation and identification of the substance present in culture broth of Streptomyces carpaticus which showed high biological activity against human tumor cell lines HL-60 (promyelocytic leukemia), MDA-MB 435 (breast carcinoma ), HCT-8 (colon carcinoma), SF-295 (glioblastoma). Cultures of Streptomyces carpaticus in cultu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/09/2011
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6. Analysis of antimicrobial, cytotoxic and mutagenic potencial of extracts and substances obteined of diferente species of Piper / Análise do potencial antimicrobiano, citotóxico e mutagênico de extratos e substâncias obtidas de diferentes espécies de Piper
The infectious diseases are now one of the major causes of death in all over the world. The appearance of emerging infectious diseases and the problem of microbial resistance has driven the research for new antimicrobial agents. A thousand of years the medicinal plants has been used by your properties of healing. From this utilization scientific studies has
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011
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7. Correlação entre os ensaios de citotoxicidade em Artemia salina Leach e atividade antineoplásica sobre linhagens de células tumorais para algumas classes de produtos naturais / Correlation between the citotoxicity assays in Artemia salina Leach and antineoplasic activity on tumoral cell lines for some natural products groups
The aim of this study was to correlate qualitative and quantitatively the lethal concentration needed for the citotoxic test on Artemia salina with the inhibitory concentration for the growth of tumoral cell lines using ten pure substances already known. Estimates for the year 2008 and also valid for the year 2009, in Brazil, show the occurrence of 466.730 n
Publicado em: 2009
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8. Biological activity of amides and analogs from Piper species and synthetic analogs / Atividade biológica de amidas e análogos de espécies de Piper e estudos biossintéticos
Six amides were isolated from Piper scutifolium and P. corcovadensis including piperovatine, piperlonguminine, isopiperlonguminine and corcovadine, the new scutifoliamide A and scutifoliamide B and also two aristolactams (piperolactam C and stigmalactam). From P. tuberculatum the amides piplartine and pellitorine and two esters, ethyl (E)-3,4,5-trimethoxycin
Publicado em: 2009
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9. Avaliao das atividades biolgicas de espcies do gnero Lychnophora (arnicas) e Estudo fitoqumico do extrato ativo de Lychnophora staavioides Mart. / Avaliao das atividades biolgicas de espcies do gnero Lychnophora (arnicas) e Estudo fitoqumico do extrato ativo de Lychnophora staavioides Mart.
Twenty-two extracts from five Lychnophora species and one Lychnophoriopsis species, traditionally used in Brazil as analgesic, antiinflammatory, and to treat bruise and rheumatism were examined for the inhibition of xanthine oxidase (XO), the antioxidant activity, the citotoxic activity and the phytochemical study of the chloroform extracts from Lychnophora
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/02/2008
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10. Purificação e caracterização de uma toxina enterotóxica, citotóxina e letal produzida por amostras de Plesiomonas shigelloides isoladas de água de rio. / Purification and caracterization of an enterotoxic, cytotoxic and lethal toxin produced by Plesiomonas shigelloides isolated from river water.
Plesiomonas shigelloides is a ubiquous microorganism recognized as putative human and animal enteropathogen. Production of toxins has been related to their role in pathogenicity. At previous studies we detected a cytotoxin, named LCF (Lethal Citotoxic Factor) active on a variety of cells, causing intensive intracellular vacuolation and nuclear condensation,
Publicado em: 2008
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11. Chemical characterization and antioxidant and citotoxic activities from alecrim propolis / Análise química e atividades antioxidante e citotóxica de amostras de própolis de alecrim
Propolis is a complex mixture of substances derived from bee products and plant resins. Propolis color and texture vary widely and chemical composition is dependent on the hive locality. Bees use propolis to seal openings in the hive and to line it internally, which help keeping the environment aseptic. Propolis properties in medicine has been known since an
Publicado em: 2008
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12. Contribuição ao Conhecimento Químico de Esponjas do Litoral Cearense: Monanchora arbuscula / Contribution to Knowledge of Chemical Sponges Coastal Ceará: Monanchora arbuscula
Monanchora arbuscula (DUCHASSAING &MICHELOTTI, 1864) (Crambeidae) is an incrustant sponge, massive or branched with 15 cm high. Its color ranges from salmon to bright red or light pink with white conspicuous channels. Previous studies of M. arbuscula led to the isolation of some polycyclic guanidine alkaloids; ptilocaulin, 8bhydroxyptilocaulin, dehydrobatzel
Publicado em: 2008