Clinical Method
Mostrando 1-12 de 4842 artigos, teses e dissertações.
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1. Molecular epidemiology and antifungal susceptibilities of Aspergillus species isolated from patients with invasive aspergillosis
SUMMARY OBJECTIVE: The aim of this study was to evaluate the demographic data, molecular epidemiology, and in vitro antifungal susceptibility results of patients with Aspergillus isolated from various clinical specimens. METHODS: A total of 44 Aspergillus strains were studied. The definition of invasive aspergillosis in patients was made according to Europ
Revista da Associação Médica Brasileira. Publicado em: 2023
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2. Systematic review on fecal calprotectin in cystic fibrosis
Abstract Objectives: Fecal calprotectin is an inflammatory marker used for monitoring intestinal diseases. It has been studied as a marker of intestinal inflammation in cystic fibrosis (CF), a multi-systemic genetic disease caused by alterations to the CFTR gene. Manifestations of the disease favor a systemic inflammation not limited to the respiratory trac
Jornal de Pediatria. Publicado em: 2023
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3. Clinical and epidemiological characteristics and individual experiences of illness in men with COVID-19: mixed method study
ABSTRACT BACKGROUND: Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, studies have shown that this disease has affected the male population on a significant scale in various parts of the world, making men one of the main risk groups. OBJECTIVE: To analyze the clinical and epidemiological characteristics and experiences of illness
Sao Paulo Medical Journal. Publicado em: 2022
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4. Decision tree-based classification as a support to diagnosis in the Alzheimer’s disease continuum using cerebrospinal fluid biomarkers: insights from automated analysis
Objective: Cerebrospinal fluid (CSF) biomarkers add accuracy to the diagnostic workup of cognitive impairment by illustrating Alzheimer’s disease (AD) pathology. However, there are no universally accepted cutoff values for the interpretation of AD biomarkers. The aim of this study is to determine the viability of a decision-tree method to analyse CSF bioma
Brazilian Journal of Psychiatry. Publicado em: 2022
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5. Association of FOXO3 polymorphism (rs3800231) and clinical subphenotypes of beta thalassemic individuals
Abstract Introduction Studies have shown that the loss of the FOXO3 transcriptional function is involved in the pathophysiology of some chronic erythroid disorders, including beta-thalassemia (β-thal). Therefore, the single nucleotide polymorphism (SNP) rs3800231 (35-2764A > G) could contribute to alterations in its transcriptional activity, acting as a mo
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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6. Sebaceous nevus of Jadassohn: review and clinical-surgical approach
Abstract Background: Nevus sebaceous of Jadassohn is defined as a rare congenital malformation characterized as a non-hereditary hamartoma of the adnexal structures of the skin. Its etiology is not yet well understood, but it is believed to be related to post-zygotic mutations in the HRAS, NRAS and KRAS genes. Objective: To describe the clinical manifestat
Anais Brasileiros de Dermatologia. Publicado em: 2022
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7. Effect of Kangaroo Position on microcirculation of preterm newborns: a controlled randomized clinical trial
Abstract Objective: The objective of this study was to evaluate the effect of Kangaroo Position (KP) in microcirculation (MC) of the flexor muscles of preterm newborns. Method: A controlled clinical trial was conducted in the city of Recife, Brazil, with 26 preterm children randomized in the Kangaroo Group (13) and in the Control Group (13). Assessments of
Jornal de Pediatria. Publicado em: 2022
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8. Mechanical Circulatory Assist Devices: Which Is the Best Device as Bridge to Heart Transplantation?
ABSTRACT Introduction: Heart transplantation is the recommended treatment method for patients with advanced heart failure that is refractory to clinical treatment. Due to the progressive severity of these patients and the impossibility of performing the transplant in a short term, there are mechanical circulatory assist devices that can offer necessary hemo
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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9. Performance and reference intervals of thrombin generation test: results from the Brazilian longitudinal study of adult health (ELSA-Brasil). A cross-sectional study
ABSTRACT BACKGROUND: The thrombin generation test (TGT) has shown promise for investigation of hemorrhagic and thrombotic diseases. However, despite its potential, it still needs standardization. Moreover, few studies have established reference values for TGT parameters. In Brazil, these values have not yet been established. OBJECTIVE: To determine TGT per
Sao Paulo Medical Journal. Publicado em: 2022
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10. Hemophagocytic lymphohistiocytosis: presentation and outcome of twenty-one patients at a single institution
ABSTRACT Introduction: Hemophagocytic lymphohistiocytosis comprises a systemic hyperactivation of macrophages that requires prompt recognition of symptoms and early treatment. Objective and Method: In this context, we described clinical and laboratory characteristics, therapeutic modality and outcome of 21 patients with HLH treated at a pediatric oncology
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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11. Minimal Invasive Thoracoscopic Mitral Valve Surgery
ABSTRACT Introduction: The totally thoracoscopic approach for mitral valve (MV) disease is a minimally invasive method. We investigated the procedure’s feasibility, safety and effectiveness when it was performed by an experienced operator. Methods: We retrospectively analysed 96 consecutive patients with MV disease treated between March 2016 and November
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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12. Comparison between intravenous and intrathecal clonidine for postoperative analgesia of patients submitted to laparoscopic cholecystectomy: randomized clinical trial
Abstract Introduction and objectives: Alpha2 adrenergic agonists, such as clonidine, are used as adjuvants during anesthesia due to their analgesic, sedative, and cardiovascular effects. The objective of the present study was to compare the effect of clonidine administered intravenously and intrathecally on the postoperative pain score of patients undergoin
Brazilian Journal of Anesthesiology. Publicado em: 2022