Clinical Toxicology
Mostrando 1-12 de 43 artigos, teses e dissertações.
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1. Kalanchoe laciniata and Bryophyllum pinnatum: an updated review about ethnopharmacology, phytochemistry, pharmacology and toxicology
Abstract The species Kalanchoe laciniata (L.) DC. and Bryophyllum pinnatum (Lam) Pers. are native from Brazil and Madagascar, respectively. Both belonging to the Crassulaceae family and being widely used by population as a natural anti-inflammatory agent. These species have similar leaf morphology and for this reason, they are known by the same popular name
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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2. METABOLÔMICA: DEFINIÇÕES, ESTADO-DA-ARTE E APLICAÇÕES REPRESENTATIVAS
Metabolomics is an emerging and promising omics approach used to understand biological mechanisms. By untargeted and targeted metabolomics analyses, metabolites are determined in biological samples (fluids, cells, tissues, etc.) by comparison of control groups with altered groups, undergoing different therapies, submitted to differing stress levels, dietary
Quím. Nova. Publicado em: 2018-01
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3. Justicia pectoralis, a coumarin medicinal plant have potential for the development of antiasthmatic drugs?
ABSTRACT Justicia pectoralis Jacq., Acanthaceae, is a medicinal plant found Central America. In the Northeast of Brazil, it is popularly known as “chambá” being extensively used in homemade preparations for the treatment of cough, bronchitis and asthma. The species is part of a public phytotherapy program in Brazil entitled “Farmácias Vivas”, Natio
Rev. bras. farmacogn.. Publicado em: 2017-12
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4. Non-clinical studies in the process of new drug development - Part II: Good laboratory practice, metabolism, pharmacokinetics, safety and dose translation to clinical studies
The process of drug development involves non-clinical and clinical studies. Non-clinical studies are conducted using different protocols including animal studies, which mostly follow the Good Laboratory Practice (GLP) regulations. During the early pre-clinical development process, also known as Go/No-Go decision, a drug candidate needs to pass through severa
Braz J Med Biol Res. Publicado em: 12/12/2016
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5. Cocaine/levamisole-induced systemic vasculitis with retiform purpura and pauci-immune glomerulonephritis
Levamisole has been increasingly used as an adulterant of cocaine in recent years, emerging as a public health challenge worldwide. Levamisole-associated toxicity manifests clinically as a systemic vasculitis, consisting of cutaneous, hematological, and renal lesions, among others. Purpura retiform, cutaneous necrosis, intravascular thrombosis, neutropenia,
Braz J Med Biol Res. Publicado em: 26/04/2016
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6. Carthami flos: a review of its ethnopharmacology, pharmacology and clinical applications
ABSTRACTCarthami flos, the dried floret of Carthamus tinctorius L., Asteraceae (safflower), has been widely used in traditional Chinese medicine to treat a broad range of ailments, such as coronary heart disease, angina pectoris, gynecologic disease, stroke, and hypertension. However, although several studies on Carthami flos have been done consecutively, th
Rev. bras. farmacogn.. Publicado em: 2015-10
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7. Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review
Cocos nucifera (L.) (Arecaceae) is commonly called the “coconut tree” and is the most naturally widespread fruit plant on Earth. Throughout history, humans have used medicinal plants therapeutically, and minerals, plants, and animals have traditionally been the main sources of drugs. The constituents of C. nucifera have some biological effects, such as a
Braz J Med Biol Res. Publicado em: 18/08/2015
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8. Estudo de Toxicologia ClÃnica e EficÃcia TerapÃutica do Fitomedicamento MelagriÃo / Clinical Toxicology and Therapeutic Efficacy Study of MelagriÃo phytomedicine.
O expectorante MelagriÃo à um fitoterÃpico composto de seis plantas medicinais com conhecida aÃÃo no trato respiratÃrio: Mikania glomerata, Cephaelis ipecacuanha, Aconitum napellus, Polygala senega, Myroxylon balsamum e Nasturtium officinale. O objetivo desse estudo foi avaliar a seguranÃa, o potencial genotÃxico do MelagriÃo em voluntÃrios sad
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/06/2011
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9. Toxicología clínica comunitaria
In some Latin American countries acute intoxication is professionally managed by specialized physicians qualified in the area. Something similar occurs with work-related chronic intoxication in the formal sector. However, a different reality prevails for the assessment of chronic intoxication of environmental origin, since it is by definition more difficult
Ciência & Saúde Coletiva. Publicado em: 2011-08
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10. ASSISTÊNCIA HUMANIZADA EM TOXICOLOGIA CLÍNICA NO SISTEMA ÚNICO DE SAÚDE DO CEARÁ: ESTUDO DE CASO NO HOSPITAL GERAL DE FORTALEZA / ASSISTANCE IN TOXICOLOGY HUMANIZED CLINIC IN UNIFIED HEALTH SYSTEM CEARÁ: CASE STUDY IN GENERAL HOSPITAL OF FORTALEZA
O presente trabalho se dedica ao estudo de caso de assistência humanizada em toxicologia clínica no Hospital Geral de Fortaleza. Este hospital do Sistema Único de Saúde do Ceará é referência no atendimento e no fornecimento de informações para tratamento de pessoas intoxicadas e com acidentes por animais peçonhentos no Estado a partir de novembro d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/04/2010
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11. Estudo de toxicologia clÃnica da tintura de Jalapa na constipaÃÃo intestinal. / Study of clinical toxicology of the dye of Jalapa in the intestinal constipation.
A Tintura de Jalapa à um fitoterÃpico extraÃdo da planta Operculina alata (Ham) Urban conhecida popularmente como aguardente alemà e de uso bastante extenso pela populaÃÃo. Este fitoterÃpico tem aÃÃes laxativas e purgativas e pertence à famÃlia Convolvulaceae composta de 51 gÃneros com ampla distribuiÃÃo em regiÃes tropicais e subtropicais. Ã
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/08/2009
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12. AvaliaÃÃo da seguranÃa e genotoxicidade do chà de Alpinia zerumbet (pers.) Burrt &Smith em voluntÃrios sadios. / Safety and genotoxicity evaluation of the Alpinia zerumbet (pers.) Burtt &Smith tea on healthy volunteers.
Alpinia zerumbet, popularly known as Colonia in the Northeast of Brazil, is a medicinal plant widely used in the popular medicine as a tea, being traditionally used to treat arterial hypertension. The objective of this study was to evaluate the safety and genotoxic potential of the A. zerumbet tea in healthy volunteers. Clinical trial consisted of a double-b
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/01/2009