Clostridium Difficile Toxin A
Mostrando 1-12 de 243 artigos, teses e dissertações.
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1. Detection of vancomycin-resistant enterococci (VRE) in stool specimens submitted for Clostridium difficile toxin testing
Abstract The aim of this study was to determine the association between Clostridium difficile (C. difficile) and vancomycin-resistant Enterococcus (VRE) and efficacy of screening stools submitted for C. difficile toxin assay for prevalence of VRE. Between April 2012 and February 2014, 158 stool samples submitted for C. difficile toxin to the Marmara Universi
Braz. J. Microbiol.. Publicado em: 2017-07
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2. Antimicrobial susceptibility of Brazilian Clostridium difficile strains determined by agar dilution and disk diffusion
Abstract Clostridium difficile is a leading cause of diarrhea in hospitalized patients worldwide. While metronidazole and vancomycin are the most prescribed antibiotics for the treatment of this infection, teicoplanin, tigecycline and nitazoxanide are alternatives drugs. Knowledge on the antibiotic susceptibility profiles is a basic step to differentiate rec
Braz J Infect Dis. Publicado em: 2016-10
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3. Detection of toxins A/B and isolation of Clostridium difficile and Clostridium perfringens from dogs in Minas Gerais, Brazil
The objective of this study was to detect C. difficileA/B toxins and to isolate strains of C. perfringensand C. difficile from diarrheic and non-diarrheic dogs in Brazil. Stool samples were collected from 57 dogs, 35 of which were apparently healthy, and 22 of which were diarrheic. C. difficileA/B toxins were detected by ELISA, and C. perfringensand C. diffi
Braz. J. Microbiol.. Publicado em: 26/03/2013
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4. Clinical importance and representation of toxigenic and non-toxigenic Clostridium difficile cultivated from stool samples of hospitalized patients
The aim of this study was to fortify the clinical importance and representation of toxigenic and non-toxigenic Clostridium difficile isolated from stool samples of hospitalized patients. This survey included 80 hospitalized patients with diarrhea and positive findings of Clostridium difficile in stool samples, and 100 hospitalized patients with formed stool
Brazilian Journal of Microbiology. Publicado em: 2012-03
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5. GTPases Rho e o potencial regenerativo da retina de mamíferos / Rho GTPases and the regenerative potential of the mammalian retina
Ciliary Body (CB) is a potential source of stem cells in the adult retina, but its activation is still unknown. Rho GTPases play a role in actin-based cytoskeleton reorganization, regulate signaling pathways and gene transcription, cell survival and cell proliferation. In this study we investigated the expression of Rho GTPases in CB cells and their role on
Publicado em: 2010
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6. The effect of the adenosine deaminase inhibitor, EHNA, on Clostridium difficile toxin-A-induced enteritis in murine ileal loops / Estudo do efeito do inibidor da enzima adenosina desaminase, EHNA, sobre a enterite induzida pela toxina a do Clostridium difficile em alÃa ileal isolada de camundongos
O Clostridium difficile tem como principal fator de virulÃncia a toxina A (TxA), a qual provoca inflamaÃÃo e destruiÃÃo tecidual aguda em intestinos de animais experimentais e de pacientes com a doenÃa induzida por esta bactÃria. Em locais de injÃria tecidual, adenosina à produzida em altas concentraÃÃes, onde exerce uma sÃrie de efeitos antiinfl
Publicado em: 2008
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7. ModulaÃÃo do retinol na lesÃo da barreira morfofuncional induzida pela toxina A do Clostridium difficile em culturas de cÃlulas intestinais / Retinol modulation protecting the morfofunctional barrier challenged the Clostridium difficile Toxin A in intestinal cell lines
Vitamin A (retinol) is an essential nutrient that is necessary in small amounts for normal functioning of the visual system, immune function and reproduction. Our group has investigated the effect of oral dosis of vitamin A on the early childhood diarrhea in our prospective community-based studies in high endemic areas in the Northeast of Brazil and has foun
Publicado em: 2007
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8. Study of a new adenosine receptor A2A agonist, ATL313, on Clostridium difficile toxin A-induced enteritis in ileal pouch isolated of mice / Estudo do efeito de um novo agonista do receptor a2a de adenosina, atl313, sobre a enterite induzida pela toxina a do clostridium difficile em alça ileal isolada de camundongos
C. difficile toxin A (TxA) plays an important pathogenic role in antibiotic-induced diarrhea and pseudomembranous colitis, a condition characterized by intense mucosal inflammation and secretion. Agonist activity at A2A adenosine receptors (A2A ARs) attenuates inflammation and damage in many tissues. This study evaluated the effect of a new selective A2A AR
Publicado em: 2005
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9. Prevalência do clostridium difficile e associação com a antibióticoterapia em um grupo de indivíduos do sul do Brasil
O Clostridium difficile (Cd) é um bacilo Gram-positivo, anaeróbio, formador de esporos, amplamente distribuído no ambiente hospitalar, fazendo parte da microbiota do trato gastrointestinal de humanos e animais. Está associado com a colite pseudomembranosa (PMC) e outras desordens intestinais, tais como diarréia, em virtude do uso prévio de antimicrobia
Publicado em: 2005
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10. Mecanismo de transporte iônico em íleo de coelho, induzido por microcistina LR de Microcystis aeruginos: Participação de macrófagos,Il-1beta, TNFalpha e mediadores pró-inflamatórios / Mechanism of ionic transport in ileum rabbit induced by microcystin-LR of Microcystis aeruginosa: Role of macrophages, IL-1b, TNF-a and pro-inflammatory mediators
This work as main objective to evaluate the eletrogenic effect in preparations of íleum of rabbit fixes in chambers of Üssing, in presence of supernatant of macrophages (S.MfS), stimulated with microcistin-LR (MCLR), of Microcystis aeruginosa. S.MfS estimulated with MCLR (3,2.10-7M; 9,6.10-7M e 3,2.10-6M), produces effect secretion, of the form dose-depend
Publicado em: 2003
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11. Clonal Spread of a Clostridium difficile Strain with a Complete Set of Toxin A, Toxin B, and Binary Toxin Genes among Polish Patients with Clostridium difficile-Associated Diarrhea
Clinically relevant Clostridium difficile strains usually produce toxins A and B. Some C. difficile strains can produce an additional binary toxin. We report clonality among five strains carrying all toxin genes from Polish patients with C. difficile-associated diarrhea. In another strain, possible recombination between binary toxin genes is documented.
American Society for Microbiology.
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12. Nontoxigenic strains of Clostridium difficile lack the genes for both toxin A and toxin B.
A total of 39 toxigenic and 20 nontoxigenic strains of Clostridium difficile were tested for the presence of either toxin A or toxin B by the polymerase chain reaction (PCR). All toxigenic strains produced cytotoxin as assayed by using highly sensitive fetal lung fibroblasts and were positive for toxin A as well as toxin B in the PCR assay. All nontoxigenic