Clusterin
Mostrando 1-12 de 32 artigos, teses e dissertações.
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1. Circulating IL-6, clusterin and irisin in obese subjects with different grades of obesity: association with insulin resistance and sexual dimorphism
ABSTRACT Objective: There are discrepancies about the relationship of IL-6, clusterin and irisin with obesity and obesity associated insulin resistance and also about their sexual dimorphism. This study aimed at evaluating the circulating levels of IL-6, clusterin and irisin in obese subjects of both sexes who had different grades of obesity and examining t
Arch. Endocrinol. Metab.. Publicado em: 2021-04
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2. Errata
ABSTRACT Objective: There are discrepancies about the relationship of IL-6, clusterin and irisin with obesity and obesity associated insulin resistance and also about their sexual dimorphism. This study aimed at evaluating the circulating levels of IL-6, clusterin and irisin in obese subjects of both sexes who had different grades of obesity and examining t
Rev. contab. finanç.. Publicado em: 2021-04
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3. Estudo dos Polimorfismos dos Genes CLU e CR1 na depressão e na demência de Alzheimer de início tardio em idosos brasileiros
A demência e a depressão representam causas importantes de dependência e incapacidade entre os idosos, com profundas consequências para a família e o sistema de saúde. O estudo dos biomarcadores é fundamental para a compreensão dos mecanismos fisiopatológicos da doença e, consequentemente, para o diagnóstico precoce e busca de novos alvos terapêu
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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4. ProteÃnas do plasma seminal de touros Bos Indicus e associaÃÃes com parÃmetros seminais / Proteins of seminal plasma of bulls Bos indicus and associations with semen parameters
This research aimed to describe the two-dimensional electrophoresis map of bull seminal plasma of adult Bos indicus, Brahman, and the determination of statistical associations between proteins of seminal plasma and semen parameters of these bulls. Semen samples from 56 bulls were collected and seminal plasma was obtained by centrifugation and subjected to tw
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/03/2011
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5. Busca e recuperaÃÃo de componentes de software utilizando agrupamento de componentes
The development of software with reuse is an approach that can be used to achieve two main benefits: (1) increase in productivity of software projects and (2) improvements in the final quality of the products. The software reuse approach can be instantiated through the strategy of development based in software components. According to this strategy, large so
Publicado em: 2008
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6. Clusterin promotes the aggregation and adhesion of renal porcine epithelial cells.
The function of clusterin, a heterodimeric glycoprotein markedly induced in renal and other organ injuries, is unclear. Since renal injury is accompanied by alterations in cell attachment, it is possible that clusterin functions to promote cell-cell and cell-substratum interactions. In this study, a single cell suspension of renal epithelial (LLC-PK1) cells
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7. Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease
Studies have shown that clusterin (also called apolipoprotein J) can influence the structure and toxicity of amyloid-β (Aβ) in vitro. To determine whether endogenous clusterin plays a role in influencing Aβ deposition, structure, and toxicity in vivo, we bred PDAPP mice, a transgenic mouse model of Alzheimer's disease, to clusterin−/− mice. By 12 mont
National Academy of Sciences.
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8. Clusterin, a putative complement regulator, binds to the cell surface of Staphylococcus aureus clinical isolates.
The ability of Staphylococcus aureus Cowan I strain and a number of S. aureus clinical isolates to bind to the human blood glycoprotein clusterin was investigated. Binding of clusterin to these strains was tested by both enzyme-linked immunosorbent assay and flow cytometry. All of the S. aureus strains examined appeared to bind clusterin to some extent, whil
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9. Human seminal clusterin (SP-40,40). Isolation and characterization.
Molecular cloning of the human complement inhibitor SP-40,40, has revealed strong homology to a major rat and ram Sertoli cell product, sulfated glycoprotein-2, known also as clusterin. This study reports the purification and characterization of human seminal clusterin. Two-dimensional gel electrophoresis revealed charge differences between clusterin purifie
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10. Distinct sites of production and deposition of the putative cell death marker clusterin in the human thymus.
Clusterin is a multifunctional protein endowed with cell-aggregating, complement-inhibitory, and lipid-binding properties. Since several studies have demonstrated highly increased clusterin gene expression in epithelial and nervous tissues regressing as a consequence of tissue involution and apoptotic cell death, clusterin is also considered as a specific ma
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11. Apolipoprotein J/Clusterin Prevents a Progressive Glomerulopathy of Aging
Apoliprotein J (apoJ)/clusterin has attracted considerable interest based on its inducibility in multiple injury processes and accumulation at sites of remodeling, regression, and degeneration. We therefore sought to investigate apoJ/clusterin's role in kidney aging, as this may reveal the accumulated effects of diminished protection. Aging mice deficient in
American Society for Microbiology.
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12. Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death.
Clusterin is a serum glycoprotein endowed with cell aggregating, complement inhibitory, and lipid binding properties, and is also considered as a specific marker of dying cells, its expression being increased in various tissues undergoing programmed cell death (PCD). However, no study has so far directly shown that cells expressing clusterin in these tissues