Coelomocytes
Mostrando 1-12 de 12 artigos, teses e dissertações.
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1. Mecanismos celulares e teciduais da regeneração em holotúrias (Echinodermata:Holothuroidea) / Cellular and tecidual mechanisms of regeneration in sea cucumbers (Echinodermata: Holothuroidea)
Equinodermos são bem conhecidos pelas suas grandes capacidades regenerativas, principalmente em processos mais complexos como a reposição de membros e órgãos. Porém pouco se sabe sobre processos aparentemente mais simples como a cicatrização. Tem sido descrito que um dos principais mecanismos envolvidos neste evento é o remodelamento da matriz extra
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/09/2011
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2. Cellular and biochemical responses to environmental and experimentally induced stress in sea urchin coelomocytes
Coelomocytes are considered to be immune effectors of sea urchins. Subpopulations of coelomocytes can be purified from a total cell suspension. The proportion of each cell type can vary not only among species, but also between individuals of the same species, according to their size and physiological conditions. We tested the hypothesis that coelomocytes pla
Cell Stress Society International.
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3. Dynamic expression of multiple scavenger receptor cysteine-rich genes in coelomocytes of the purple sea urchin
Coelomocytes, the heterogeneous population of sea urchin putative immune cells, were found to express a complex set of transcripts featuring scavenger receptor cysteine-rich (SRCR) repeats. SRCR domains define a metazoan superfamily of proteins, many of which are implicated in development and regulation of the immune system of vertebrates. Coelomocytes
The National Academy of Sciences.
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4. RME-8, a Conserved J-Domain Protein, Is Required for Endocytosis in Caenorhabditis elegans
By genetic analysis of Caenorhabditis elegans mutants defective in yolk uptake, we have identified new molecules functioning in the endocytosis pathway. Here we describe a novel J-domain–containing protein, RME-8, identified by such genetic analysis. RME-8 is required for receptor-mediated endocytosis and fluid-phase endocytosis in various cell types
The American Society for Cell Biology.
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5. Evolutionary conservation of the AU-rich 3' untranslated region of messenger RNA.
AU-rich sequence motifs (specifically sequences containing reiterations of AUUUA) are found in the 3' untranslated region of mammalian mRNAs encoding cytokines, adhesion molecules, and protooncogenes. Because these AU-rich elements (3'AURE) have been observed to reduce the stability and translational efficiency of transcripts that contain them, and because m
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6. SpCoel1: a sea urchin profilin gene expressed specifically in coelomocytes in response to injury.
SpCoel1 is a single copy gene that is specifically expressed in most of the coelomocytes of the adult purple sea urchin, Strongylocentrotus purpuratus. The 4-kb transcript from this gene has a relatively short (426 nucleotide) open reading frame (ORF) with long 3' and 5' untranslated regions. The ORF encodes a protein that has strong amino acid sequence simi
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7. Two Components of Actin-based Retrograde Flow in Sea Urchin Coelomocytes
Sea urchin coelomocytes represent an excellent experimental model system for studying retrograde flow. Their extreme flatness allows for excellent microscopic visualization. Their discoid shape provides a radially symmetric geometry, which simplifies analysis of the flow pattern. Finally, the nonmotile nature of the cells allows for the retrograde flow to be
The American Society for Cell Biology.
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8. Isolation and characterization of a primitive interleukin-1-like protein from an invertebrate, Asterias forbesi.
Interleukin 1 (IL-1) is the major immunoregulatory molecule produced by macrophages and other related cells. It acts as the molecular orchestrator of nonspecific host defense mechanisms against multifarious insults. In this study we report the characterization of an IL-1-like protein from the starfish Asterias forbesi. IL-1-like activity was found in the coe
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9. Wound Closure in the Lamellipodia of Single Cells: Mediation by Actin Polymerization in the Absence of an Actomyosin Purse String
The actomyosin purse string is an evolutionarily conserved contractile structure that is involved in cytokinesis, morphogenesis, and wound healing. Recent studies suggested that an actomyosin purse string is crucial for the closure of wounds in single cells. In the present study, morphological and pharmacological methods were used to investigate the role of
The American Society for Cell Biology.
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10. Calreticulin, a Calcium-binding Molecular Chaperone, Is Required for Stress Response and Fertility in Caenorhabditis elegans
Calreticulin (CRT), a Ca2+-binding protein known to have many cellular functions, including regulation of Ca2+ homoeostasis and chaperone activity, is essential for heart and brain development during embryogenesis in mice. Here, we report the functional characterization of Caenorhabditis elegans calreticulin (crt-1). A crt-1 null mutant does not result
The American Society for Cell Biology.
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11. Disease-related Myotubularins Function in Endocytic Traffic in Caenorhabditis elegansD⃞
MTM1, MTMR2, and SBF2 belong to a family of proteins called the myotubularins. X-linked myotubular myopathy, a severe congenital disorder characterized by hypotonia and generalized muscle weakness in newborn males, is caused by mutations in MTM1 (Laporte et al., 1996). Charcot-Marie-Tooth types 4B1 and 4B2 are severe demyelinating neuropathies caused by muta
The American Society for Cell Biology.
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12. Contribution of the GTPase Domain to the Subcellular Localization of Dynamin in the Nematode Caenorhabditis elegans
Caenorhabditis elegans dynamin is expressed at high levels in neurons and at lower levels in other cell types, consistent with the important role that dynamin plays in the recycling of synaptic vesicles. Indirect immunofluorescence showed that dynamin is concentrated along the dorsal and ventral nerve cords and in the synapse-rich nerve ring. Green fluo
The American Society for Cell Biology.