Controlled Drug Release
Mostrando 1-12 de 161 artigos, teses e dissertações.
-
1. Da Vinci SP radical prostatectomy: a multicentric collaboration and step-by-step techniques
ABSTRACT Introduction Several techniques of robotic-assisted radical prostatectomy (RARP) using the da Vinci SP (SP) have been described since its clearance by the FDA (Food and Drug Administration) in 2018 ( 1 , 2 ). Even with the expanding literature about this robot, the SP technology has been restricted to a few centers in the US and Asia due to the re
International braz j urol. Publicado em: 2022
-
2. Novel PEG 4000 derivatives and its use in controlled release of drug indomethacin
The insertion of functional groups in polymer compounds may facilitate their interaction with different drugs. PEG polymers are widely used for their low melting point, low toxicity, drug compatibility, and hydrophilicity. They are used as pharmaceutical excipients for the formulation of conventional or modified released drugs and are designed to be upgraded
Quím. Nova. Publicado em: 2020-06
-
3. Evaluation of polyelectrolyte and emulsion covalent crosslink of chitosan for producing mesalasine loaded submicron particles
This study evaluates various techniques for producing mesalamine (5ASA)-loaded particles employing chitosan as a biopolymer: (1) the polyelectrolyte complexation of chitosan with phthalate hypromelose (HP), (2) the chemical crosslinking of chitosan with genipin and (3) the water-in-oil emulsion method associated with chemical crosslinking with genipin. Syste
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
-
4. Effects of long-term controlled internal drug release reuse on reproductive performance, hormone profiles, and economic profit of sheep
ABSTRACT Fifty-seven multiparous Awassi ewes in the breeding season were used to compare the effects of controlled internal drug release (CIDR) reuse on hormone profiles, reproductive performance, and economic production. Ewes were randomly allotted to one of three CIDR treatments: new (control), once-used, and twice-used; treatment lasted 12 days. Blood sam
R. Bras. Zootec.. Publicado em: 28/11/2019
-
5. AVALIAÇÃO DO PERFIL DE LIBERAÇÃO DO FÁRMACO IBUPROFENO EM MEMBRANAS SIMÉTRICAS E ASSIMÉTRICAS DE ACETATO DE CELULOSE: EFEITO DA MORFOLOGIA
Cellulose derivatives still receive special attention in today biomedical applications due to their biocompatibility, ability to form resistant membranes and compatibility with various bioactive agents. In this work, cellulose acetate (CA) was used to prepare membranes with different morphologies aiming to evaluate the release profile of the drug ibuprofen (
Quím. Nova. Publicado em: 21/10/2019
-
6. Effectiveness of a low-dose Norgestomet ear implant in short-term protocols to induce estrus in ewes during the non-breeding season in Brazil.
ABSTRACT The objective of this study was to evaluate the reproductive performance of ewes subjected to a short-term protocol for estrus induction using 1 mg of Norgestomet during the non-breeding season in Brazil. A total of 84 ewes were randomly divided into two equal groups (n = 42 per group). Controlled Internal Drug Release (CIDR) containing 330 mg proge
R. Bras. Zootec.. Publicado em: 03/10/2019
-
7. CONTROLLED RELEASE OF THEOPHYLLINE-CHITOSAN COMPOSITE PARTICLES PREPARED USING SUPERCRITICAL ASSISTED ATOMIZATION
Abstract This study investigated the formation of composite particles of chitosan (CS) and theophylline (TPH) via supercritical assisted atomization (SAA) using aqueous ethanol (50%, v/v) as the solvent and supercritical CO2 as the spraying medium. According to XRD, DSC, and FTIR analyses, the crystal form of the SAA-treated TPH from the as-received TPH was
Braz. J. Chem. Eng.. Publicado em: 30/09/2019
-
8. Mass Variation Rate, in Acidic Environment, of Polyhydroxybutyrate and Chitosan matrices with Potential Application as Controlled Drug Delivery System
Polymers such as the biocompatible polyhydroxybutyrate (PHB) and the polysaccharide chitosan (Chi), a pH-sensitive polymer, have been studied for drug delivery applications and scaffolds production. In this work, matrices of PHB and Chi were produced by compression molding (SPHB-Chi) and loaded with a broad-spectrum biocide chlorhexidine (CHX) (SPHB-Chi-CHX)
Mat. Res.. Publicado em: 30/09/2019
-
9. Development and in vitro/in vivo evaluation of thermo-sensitive in situ gelling systems for ocular allergy
Ocular allergy is one of the most common disorders of the eye surface. Following diagnosis this condition is typically treated with preparations containing antihistamines. However, anatomy of the eye and its natural protective mechanisms create challenges for ocular drug delivery. Rapid elimination of antihistamine substances due to short residency times fol
Braz. J. Pharm. Sci.. Publicado em: 23/09/2019
-
10. SYNTHESIS, CHARACTERIZATION AND in vitro CYTOTOXICITY OF Acacia mearnsii PROANTHOCYANIDIN LOADED PLGA MICROPARTICLES
ABSTRACT One of the highlighted areas in the development of new materials is the generation of micro- and nanoparticles as drug carriers which allow the progress in formulations with the ability to release active agents in a controlled way. The proanthocyanidins (PAC) extracted from the bark of the Black Wattle have stood out for their biological activities.
Braz. J. Chem. Eng.. Publicado em: 15/07/2019
-
11. A brief review on hydroxyapatite production and use in biomedicine
Resumo A hidroxiapatita (HAp) é uma biocerâmica amplamente estudada devido à sua similaridade química com o componente mineral dos ossos. Além disso, é biocompatível, bioativa e termodinamicamente estável no fluido corporal, o que a coloca como um material atraente para uma ampla gama de aplicações no campo biomédico. Diversos esforços têm sido
Cerâmica. Publicado em: 06/06/2019
-
12. Development and evaluation of multiparticulate biphasic system for the treatment of circadian diseases
Multiparticulate systems have biopharmaceutical advantages when compared to the monolithic systems, once they allow different patterns of drug release and can be used in different treatments. The aim of the present work was to develop a biphasic controlled release delivery system, using propranolol hydrochloride (PROP) that can be used for the treatment of c
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019