Corpora Cavernosum
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Stereological analysis of elastic fibers of the corpus cavernosum of rats during the aging process
Abstract Purpose To evaluate changes in the quantity of elastic fibers in the corpora cavernosa of rats during the natural aging process, and to assess the degree of this change by determining volumetric density (Vv) at different ages via stereological analysis. Methods Forty-eight rats, raised under similar conditions, were subjected to the natural agin
Acta Cir. Bras.. Publicado em: 14/10/2019
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2. Expression profile of endothelin receptors (ETA and ETB) and microRNAs-155 and -199 in the corpus cavernosum of rats submitted to chronic alcoholism and diabetes mellitus
Recent evidence shows that chronic ethanol consumption increases endothelin (ET)-1 induced sustained contraction of trabecular smooth muscle cells of the corpora cavernosa in corpus cavernosum of rats by a mechanism that involves increased expression of ETA and ETB receptors. Our goal was to evaluate the effects of alcohol and diabetes and their relationship
Braz J Med Biol Res. Publicado em: 01/03/2018
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3. Receptores de membrana para peptídeos natriuréticos em corpos cavernosos humanos: aspectos moleculares e funcionais. / Membrane receptors for natriuretic peptides in human corpus cavernosum: functional and molecular aspects.
Os receptores para peptídeos natriuréticos têm se mostrado alvos potenciais para o tratamento da disfunção erétil masculina, devido ao fato de os agonistas de GC de membrana elevarem os níveis intracelulares de GMPc, promovendo o relaxamento do músculo liso de corpos cavernosos humanos. Dessa forma, investigamos o efeito Peptídeo Natriurético Atria
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/06/2008
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4. Cavernous body reduction in four patients with erectile dysfunction due to insufficient venous occlusion and a deficit of elastic fibers in the tunica albugínea
INTRODUCTION: The corpora cavernosa are cylindrical vessels containing fluid under pressure. Thus, if cavernous wall resistance decreases, the radius increases and internal pressure decreases (LaPlace's law). We reasoned that if we decrease the corpus cavernosum radius, by excising a strip from each tunica albuginea, intracavernous pressure would increase du
International braz j urol. Publicado em: 2007-12
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5. A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle.
This study was initiated to characterize nonadrenergic-noncholinergic (NANC) inhibitory neurotransmission in penile corpus cavernosum. Using organ baths, isometric tension measurements were made in strips of human and rabbit corpus cavernosum. In examining endothelium-mediated responses, cumulative additions of exogenous acetylcholine elicited dose-dependent
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6. Vascular changes during penile erection in the dog.
1. The vascular effects of pelvic nerve stimulation on the penis were studied in dogs anaesthetized with sodium pentobarbitone and halothane. Changes in pressure and blood flow were measured through scalp vein needles inserted into the erectile bodies. 2. The penis contains two types of erectile body, which responded independently during erection induced by
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7. Erectile dysfunction in cyclic GMP-dependent kinase I-deficient mice
The generation of nitric oxide (NO) in penile erectile tissue and the subsequent elevation of cyclic GMP (cGMP) levels are important for normal penile erection. Current treatments of erectile dysfunction elevate either cGMP levels by blocking cGMP degrading phosphodiesterase 5 or cyclic AMP (cAMP) levels by intrapenile injection of prostaglandin E1. The mole
The National Academy of Sciences.
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8. Gene transfer of endothelial nitric oxide synthase to the penis augments erectile responses in the aged rat
Nitric oxide (NO), a mediator involved in penile erection, is synthesized by the nitric oxide synthase (NOS) family of enzymes. It has been shown that NOS activity decreases with age. To determine whether adenoviral-mediated overexpression of endothelial NOS (eNOS) could enhance erectile responses, we administered a recombinant adenovirus containing the eNOS
The National Academy of Sciences.