Corynebacterium Diphtheria
Mostrando 1-12 de 93 artigos, teses e dissertações.
-
1. Corynebacterium diphtheriae putative tellurite-resistance protein (CDCE8392_0813) contributes to the intracellular survival in human epithelial cells and lethality of Caenorhabditis elegans
Corynebacterium diphtheriae, the aetiologic agent of diphtheria, also represents a global medical challenge because of the existence of invasive strains as causative agents of systemic infections. Although tellurite (TeO32-) is toxic to most microorganisms, TeO32--resistant bacteria, including C. diphtheriae, exist in nature. The presence of TeO32--resistanc
Mem. Inst. Oswaldo Cruz. Publicado em: 24/06/2015
-
2. Multiplex polymerase chain reaction to identify and determine the toxigenicity of Corynebacterium spp with zoonotic potential and an overview of human and animal infections
Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis constitute a group of potentially toxigenic microorganisms that are related to different infectious processes in animal and human hosts. Currently, there is a lack of information on the prevalence of disease caused by these pathogens, which is partially due to a red
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-05
-
3. Influência de pré-tratamentos de células epiteliais com penicilina e eritromicina na aderência e na viabilidade intracelular de Corynebacterium diphtheriae / Influence of epithelial cells pre-treatment with penicilin and erythromycin in adherence and intracellular viability of Corynebacterium diphtheriae
Diphtheria is a syndrome caused by Toxigenic Corynebacterium diphtheriae. Although immunization programs have kept diphtheria under control in the great majority of developed countries, the disease remains endemic in many parts of the world, especially in individuals partially immunized to diphtheria toxoid. Additionally, an increase in the number of cases o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/01/2012
-
4. Papel das hemaglutininas 67-72p de Corynebacterium diphtheriae na ligação a proteínas plasmáticas, superfícies celulares, invasão e indução de apoptose / Participation of hemagglutinin 67-72p of corynebacterium diphtheriae in binding to plasma proteins, cells surfaces, invasion and induction of apoptosis
Corynebacterium diphtheriae pode ser isolado tanto de quadros de difteria clássica, quanto de infecções sistêmicas, como endocardite. O fibrinogênio (Fbn) e a fibronectina (Fn) são glicoproteínas presentes na matriz extracelular de tecidos conjuntivos. A influência destas proteínas na patogênese das infecções locais e invasivas causadas por C. di
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/06/2010
-
5. Fibrinogen binds to nontoxigenic and toxigenic Corynebacterium diphtheriae strains
The production of fibrinous exudates may play an important role in determining the outcome of bacterial infection. Although pseudomembrane formation is a characteristic feature of diphtheria, little is known about the fibrinogen (Fbn)-binding properties of Corynebacterium diphtheriae strains and the influence of the gene that codes for diphtheria toxin (tox
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-08
-
6. Expression and purification of the immunogenically active fragment B of the Park Williams 8 Corynebacterium diphtheriae strain toxin
The construction of a hexahistidine-tagged version of the B fragment of diphtheria toxin (DTB) represents an important step in the study of the biological properties of DTB because it will permit the production of pure recombinant DTB (rDTB) in less time and with higher yields than currently available. In the present study, the genomic DNA of the Corynebacte
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-05
-
7. First detection of Corynebacterium ulcerans producing a diphtheria-like toxin in a case of human with pulmonary infection in the Rio de Janeiro metropolitan area, Brazil
The frequency and severity of human infections associated with Corynebacterium ulcerans appear to be increasing in different countries. Here, we describe the first C. ulcerans strain producing a diphtheria-like toxin isolated from an elderly woman with a fatal pulmonary infection and a history of leg skin ulcers in the Rio de Janeiro metropolitan area.
Memórias do Instituto Oswaldo Cruz. Publicado em: 2008-06
-
8. Prevalence of diphtheria and tetanus antibodies and circulation of Corynebacterium diphtheriae in São Paulo, Brazil
The introduction of routine vaccination against tetanus and diphtheria in Brazil has decreased the incidence and changed the epidemiology of both diseases. We then investigated the prevalence of Corynebacterium diphtheriae carrier status and diphtheria and tetanus immunity in São Paulo, Brazil. From November 2001 to March 2003, 374 individuals were tested f
Brazilian Journal of Medical and Biological Research. Publicado em: 29/10/2007
-
9. Diphtheria remains a threat to health in the developing world: an overview
Changes in the epidemiology of diphtheria are occurring worldwide. A large proportion of adults in many industrialized and developing countries are now susceptible to diphtheria. Vaccine-induced immunity wanes over time unless periodic booster is given or exposure to toxigenic Corynebacterium diphtheriae occurs. Immunity gap in adults coupled with large numb
Memórias do Instituto Oswaldo Cruz. Publicado em: 2003-12
-
10. Production of diphtheria toxin by selected isolates of Corynebacterium ulcerans and Corynebacterium pseudotuberculosis.
We determined the diphtheria toxin phenotype of specially selected isolates of Corynebacterium ulcerans and Corynebacterium pseudotuberculosis (C. ovis). All produced proteins similar in size and immunological structure to diphtheria toxin. As with diphtheria toxin, they exhibited ADP-ribosylating activity, and their synthesis was regulated by iron.
-
11. Corynebacterium ulcerans in an Immunocompromised Patient with Diphtheria and Her Dog
Corynebacterium ulcerans causes zoonotic infections, such as diphtheria and extrapharyngeal infections. We report here the first case of a diphtheria-like illness caused by C. ulcerans in France and transmitted likely by a dog to an immunocompromised woman.
American Society for Microbiology.
-
12. Detection of Differences in the Nucleotide and Amino Acid Sequences of Diphtheria Toxin from Corynebacterium diphtheriae and Corynebacterium ulcerans Causing Extrapharyngeal Infections
While Corynebacterium ulcerans can mimic classical diphtheria, extrapharyngeal infections are extremely rare. Sequencing of the diphtheria toxin (DT)-encoding tox gene of two C. ulcerans isolates from extrapharyngeal infections revealed differences from C. diphtheriae DT sequences, mainly in the translocation and receptor-binding domains. C. ulcerans superna
American Society for Microbiology.