Critical Factors In Spi
Mostrando 1-5 de 5 artigos, teses e dissertações.
-
1. Problemas em iniciativas de melhoria de processos de Software sob a Ãtica de uma Teoria de IntervenÃÃo
Software process improvement initiatives (SPI) are gaining great importance in the software industry as a factor of evolution of the quality of its products and as a response to the high rate of failure in software projects. Research shows that MPS initiatives have also a high rate of failure. They show also that many of the main critical factors in SPI are
Publicado em: 2007
-
2. Host–pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes
Nramp1 (Natural resistance-associated macrophage protein-1; also known as Slc11a1) is a host resistance gene that provides protection against several intracellular pathogens, including Salmonella enterica serovar Typhimurium. Little is known about the dynamic interplay that occurs between mammalian host resistance determinants such as Nramp1 and pathogens du
National Academy of Sciences.
-
3. Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1
The process through which multipotential hematopoietic cells commit to distinct lineages involves the induction of specific transcription factors. PU.1 (also known as Spi-1) and GATA-1 are transcription factors essential for the development of myeloid and erythroid lineages, respectively. Overexpression of PU.1 and GATA-1 can block differentiation in lineage
The National Academy of Sciences.
-
4. NF-κB protects from the lysosomal pathway of cell death
The programme of gene expression induced by RelA/NF-κB transcription factors is critical to the control of cell survival. Ligation of ‘death receptors’ such as tumor necrosis factor receptor 1 (TNF-R1) triggers apoptosis, as well as NF-κB, which counteracts this process by activating the transcription of anti-apoptotic genes. In addition to activating
Oxford University Press.
-
5. Mutations in the Salmonella enterica serovar Choleraesuis cAMP-receptor protein gene lead to functional defects in the SPI-1 Type III secretion system
Salmonella enterica serovar Choleraesuis (Salmonella Choleraesuis) causes a lethal systemic infection (salmonellosis) in swine. Live attenuated Salmonella Choleraesuis vaccines are effective in preventing the disease, and isolates of Salmonella Choleraesuis with mutations in the cAMP-receptor protein (CRP) gene (Salmonella Choleraesuis ∆crp) are the most
EDP Sciences.