Ctak1
Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. Study of protein hnRNP K, SET and MARK3 as potential markers of prognosis in squamous cell cancer of head and neck (HNSCC). / Estudos das proteínas hnRNP K, SET e MARK3 como potenciais marcadores de prognóstico em câncer epidermóide de cabeça e pescoço (HNSCC)
The head and neck cancers constitute a major public health problem due to the high incidence and some types are associated with behavioral factors such as consumption of alcohol and tobacco. Despite these data, the disease, especially in its early stage can be cured and some types can be prevented. Therefore, there is a need to identify and validate new biom
Publicado em: 2009
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2. Functional analysis of C-TAK1 substrate binding and identification of PKP2 as a new C-TAK1 substrate
Cdc25C-associated kinase 1 (C-TAK1) has been implicated in cell cycle regulation and Ras signaling through its interactions with two putative substrates, the Cdc25C phosphatase and the MAPK scaffold KSR1. Here, we identify sequence motifs required for stable C-TAK1 association and substrate phosphorylation. Using a mutational approach to disrupt binding of C
Oxford University Press.