Cytokeratin 18
Mostrando 1-12 de 49 artigos, teses e dissertações.
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1. Caracterização anatomopatológica e imuno-histoquímica dos tumores das glândulas cutâneas em cães
RESUMO O presente estudo objetivou caracterizar os aspectos anatomopatológicos e imuno-histoquímicos dos tumores das glândulas cutâneas em cães. A caracterização morfológica seguiu a classificação atualizada da Organização Mundial de Saúde. Para a caracterização imuno-histoquímica, utilizaram-se anticorpos monoclonais primários anti-citoquer
Arq. Bras. Med. Vet. Zootec.. Publicado em: 06/06/2019
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2. Primary cultures of mouse small intestinal epithelial cells using the dissociating enzyme type I collagenase and hyaluronidase
The epithelium is a highly dynamic system, which plays a crucial role in the homeostasis of the intestinal tract. However, studies on the physiological and pathophysiological functions of intestinal epithelial cells (IECs) have been hampered due to lack of normal epithelial cell models. In the present study, we established a reproducible method for primary c
Braz J Med Biol Res. Publicado em: 13/04/2017
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3. Fatores hepatotróficos modulam a capacidade proliferativa em cultura primária de hepatócitos de ratos normais / Hepatotrophic factors modulate the proliferative potential in primary hepatocyte cultures of normal rats
A utilização de fatores hepatotróficos (FH) tem trazido importantes avanços no tratamento de algumas doenças hepáticas. A avaliação dos efeitos dessas substâncias pode ser feita com o uso de modelos in vivo, como a regeneração hepática após a hepatectomia parcial ou in vitro, como a cultura de hepatócitos, células estreladas ou outros tipos ce
Publicado em: 2010
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4. Cytokeratin 19 expression in the peripheral blood mononuclear fraction of prostate cancer patients / Expressão do transcrito da citoqueratina 19 (CK-19) na fração mononuclear do sangue periférico em pacientes com adenocarcinoma de próstata
Introdução: O emprego da técnica de RT-PCR na detecção da expressão de genes epiteliais como a CK-19 no sangue periférico de pacientes com câncer de próstata é uma oportunidade para avaliar a progressão tumoral ao nível molecular na ausência de doença clinicamente mensurável. Material e métodos: Inicialmente 10 pacientes com nível sérico de
Publicado em: 2008
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5. Rhabdoid choroid plexus carcinoma: a rare histological type
Primary central nervous system atypical teratoid/rhabdoid tumors mostly occur during early childhood and are almost invariably fatal. These tumors show similar histological and radiological features to primitive neuroectodermal tumor, meduloblastoma and choroid plexus carcinoma, but present different biological behaviors. We present the case of an 18 year-ol
Arquivos de Neuro-Psiquiatria. Publicado em: 2007-09
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6. Avaliação do perfil de citoqueratinas e marcadores de proliferação celular em lesões odontogenicas : queratocisto odontogenico, cisto odontogenico ortoqueratinizado e fibroma odontogenico central / Avaliation of cytokeratin profile and celular proliferation markers in odontogenic lesions : odontogenic keratocyst, odontogenic orthokeratinized cyst and central odontogenic fibroma
A região bucomaxilofacial é freqüentemente afetada por lesões císticas e tumorais que apresentam características clínicas e histológicas heterogêneas cuja origem está associada a diversos estágios da odontogênese. Entre as lesões císticas mais freqüentes, temos o queratocisto odontogênico (QO), enquanto o cisto odontogênico ortoqueratinizado
Publicado em: 2007
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7. Interação Trypanosoma cruzi-célula hospedeira: estudo do "domínio FLY", motivo carboxi-subterminal conservado na superfamília das gp85/trans-sialidases. / Interaction between Trypanosoma cruzi and host cell: study of FLY domain, a conserved carboxil-subterminal motiv of gp85/trans-sialidases.
Trypanosoma cruzi the causative agent of Chagas´ disease is an obligatory intracellular parasite in the mammalian host. Altrough the mechanism of trypomastigotes invasion of host cells has been intensively studied, a final and integrate picture of the process remains elusive. Members of the gp85/trans-sialidase superfamily have been implicated in the parasi
Publicado em: 2006
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8. The adenovirus L3 23-kilodalton proteinase cleaves the amino-terminal head domain from cytokeratin 18 and disrupts the cytokeratin network of HeLa cells.
Immunofluorescence studies revealed that adenovirus induces a reorganization of the cytokeratin system in lytically infected HeLa cells. At 24 h postinfection, the cytokeratin network began to disassemble into prominent spheroid globules. By 36 h postinfection, host cell lysis occurred, accompanied by the formation of perinuclear cytokeratin clumps and addit
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9. Expression of cytokeratin confers multiple drug resistance.
The cytokeratin network is an extensive filamentous structure in the cytoplasm whose biological function(s) is unknown. Based upon previous data showing the modification of cytokeratin by mitoxantrone, we investigated the ability of cytokeratin networks to influence the survival response of cells to chemotherapeutic agents. We have compared the survival of m
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10. Monoclonal cytokeratin antibodies that distinguish simple from stratified squamous epithelia: characterization on human tissues.
Four monoclonal antibodies designated CK1 - CK4 were obtained from fusions of mouse myeloma F0 cells with spleen cells from BALB/c mice immunized with cytoskeletal preparations made by treatment of human HeLa cells with non-ionic detergents. These IgG1 type antibodies all recognize, in immune blots, cytokeratin 18 (45 kd, pI 5.7) in the catalogue of 19 human
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11. Cytokeratin intermediate filament expression in benign and malignant breast disease.
AIM--To carry out a comprehensive study of cytokeratin expression in benign and malignant breast epithelium and breast myoepithelial cells; to examine changes in the cytokeratin profile in malignant and benign epithelium and in carcinomas of increasing histological grade. METHODS--Frozen sections from fibroadenomas (19 cases), fibrocystic disease (19 cases),
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12. Increased IgA antibodies to cytokeratins in the spondyloarthropathies.
OBJECTIVES--Increased levels of IgA antibodies to cytokeratin-18 (CK-18) and epidermal keratins (EpK) in the sera of patients with rheumatoid arthritis (RA) have been demonstrated previously. In the present study investigations were carried out to determine whether levels of these autoantibodies were also raised in the spondyloarthropathies, and whether ther