Daidzein
Mostrando 1-12 de 59 artigos, teses e dissertações.
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1. Identification of Potential Human Protein Targets for Soybean Isoflavones
Soy isoflavones have been reported as endocrine disruptors due to their ability to modulate the activity of estrogen receptors (ERs) in mammals; however, its ability to modulate other metabolic pathways is not entirely clear, which makes it necessary to identify new pharmacological targets that interact with these compounds present in soybean. In this work,
J. Braz. Chem. Soc.. Publicado em: 2021-04
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2. Negative early life experiences as risk factors for suicidal behavior in bipolar disorders
Ultrafiltration coupled with liquid chromatography-mass spectrometry (LC-MS) was established to screen xanthine oxidase (XO) inhibitors from Pueraria lobata root extract. Four compounds were screened out and identified as puerarin, daidzin, daidzein and genistein with half-maximal inhibitory concentration (IC50) values of 30.8, 5.31, 14.5 and 3.02 µg mL−1
Braz. J. Psychiatry. Publicado em: 2020-10
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3. Pueraria lobata Root Constituents as Xanthine Oxidase Inhibitors and Protective Agents against Oxidative Stress Induced in GES-1 Cells
Ultrafiltration coupled with liquid chromatography-mass spectrometry (LC-MS) was established to screen xanthine oxidase (XO) inhibitors from Pueraria lobata root extract. Four compounds were screened out and identified as puerarin, daidzin, daidzein and genistein with half-maximal inhibitory concentration (IC50) values of 30.8, 5.31, 14.5 and 3.02 µg mL−1
J. Braz. Chem. Soc.. Publicado em: 2020-10
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4. Does mechanical damage on soybean induces the production of flavonoids?
Abstract The response of plants to grazing includes the production of chemical defense compounds such as proteases inhibitors and secondary metabolites as flavonoids, which makes them less palatable to feeding and negatively affecting the physiology of insects. The aim of this study was to evaluate the phytochemical response of soybean cultivars (Glycine max
An. Acad. Bras. Ciênc.. Publicado em: 18/10/2018
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5. Phenolic Composition and Leishmanicidal Activity of Red Propolis and Dalbergia ecastaphyllum (L.) Taub (Fabaceae) Extracts from Sergipe, Brazil
ABSTRACT Leishmaniasis is a parasitic disease caused by protozoa of the Leishmania genus. It may manifest in visceral and tegumentary forms, and pentavalent antimonials are the first choice drugs used for the treatment. Frequently these drugs show low efficiency and high toxicity to mammalian host. The present study describes the chemical profile and the in
Braz. arch. biol. technol.. Publicado em: 06/08/2018
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6. Isoflavonoid composition and biological activity of extracts from soybean seedlings treated by different elicitors
Abstract Time-course and dose-response experiments were carried out to establish the ability for synthesizing isoflavonoids of soybean seedlings (cv. Soyica P34) treated with salicylic (SA) and isonicotinic acids (INA). Then, 25 structurally-related compounds were evaluated for their isoflavonoid-eliciting activity. Next, the antimicrobial and antioxidant ac
An. Acad. Bras. Ciênc.. Publicado em: 26/07/2018
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7. Anti-inflammatory activity and chemical analysis of extracts from Trifolium riograndense
Abstract Aiming to investigate new therapeutic agents with fewer side effects, the number of studies about natural products has increased. Phenolic compounds comprise a well-studied class of abundant plant-derived compounds, whose anti-inflammatory activity has been described. Isoflavones are phenolic compounds that occur mainly in the Leguminosae family, an
Rev. bras. farmacogn.. Publicado em: 2017-06
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8. Increased antioxidant activity and polyphenol metabolites in methyl jasmonate treated mung bean (Vigna radiata) sprouts
Abstract Mung bean sprouts are a popular health food both in China and worldwide. We determined the optimal concentration of exogenous methyl jasmonate (MeJA) for the promotion of the sprouting in mung beans (Vigna radiata). The 1,1-diphenyl-2- picrylhydrazyl radical (DPPH) scavenging test showed that MeJA application resulted in significantly improved antio
Food Sci. Technol. Publicado em: 11/05/2017
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9. Isoflavone-aglycone fraction from Glycine max: a promising raw material for isoflavone-based pharmaceutical or nutraceutical products
ABSTRACT The present work was designed to obtain a fraction containing high concentration of isoflavone-aglycones from Glycine max (L.) Merr., Fabaceae, named isoflavone enriched-fraction, from a dry extract containing isoflavones-glycosides. A simple and low cost method was proposed: extraction of isoflavone glycosides from the G. max dry extract with a pro
Rev. bras. farmacogn.. Publicado em: 2016-04
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10. Application of a Quantitative HPLC-ESI-MS/MS Method for Flavonoids in Different Vegetables Matrices
Plant flavonoids have been increasingly studied for its importance in plant metabolism, inter-species interactions and human health-promoting effects. Each botanical species has a distinct flavonoid profile, and as such, this work aimed to develop and apply a high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (
J. Braz. Chem. Soc.. Publicado em: 2016-03
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11. Flavonoid profiling and nodulation of some legumes in response to the allelopathic stress of Sonchus oleraceus L.
Annual sowthistle (Sonchus oleraceus) has been reported to produce allelopathic effects. Two greenhouse experiments were conducted to estimate the allelopathic potential of both plant residue and root exudates of S. oleraceus on flavonoid composition and nodulation in a leguminous crop, Trifolium alexandrinum, and in two leguminous weeds, Melilotus indicus a
Acta Bot. Bras.. Publicado em: 2015-12
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12. Effects of caffeine, tea polyphenol and daidzein on the pharmacokinetics of lansoprazole and its metabolites in rats
resumo O objetivo deste estudo foi avaliar os efeitos da cafeína, do polifenol do chá e da daidzeína na farmacocinética do lansoprazol e de seus metabólitos. Administraram-se, intragastricamente, aos ratos cafeína (30 mg·kg-1, uma vez ao dia), polifenol do chá(400 mg·kg-1, uma vez ao dia) ou daidzeína (13,5 mg·kg-1, uma vez ao dia), por 14 dias, s
Braz. J. Pharm. Sci.. Publicado em: 2015-12