Artigos científicos, teses e dissertações
Publicados nas melhores instituições de ensino

Cyclodextrins in drug delivery: An updated review

The purpose of this review is to discuss and summarize some of the interesting findings and applications of cyclodextrins (CDs) and their derivatives in different areas of drug delivery, particularly in protein and peptide drug delivery and gene delivery. The article highlights i...

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CULTURE IN THE PROCESS OF DELIVERY: CONTRIBUTIONS TO NURSING / CULTURA NO PROCESSO DE PARTURIÇÃO: CONTRIBUIÇÕES PARA A ENFERMAGEM

The investigation aimed to understand how culture influences in the process of a woman delivery. A qualitative research with a cultural approach. The settings were a Health Center and a reference Hospital for high risk pregnancies and to gynecologic complications of a city in the...

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Operative delivery and postnatal depression: a cohort study

Objectives To assess the association between elective caesarean section and postnatal depression compared with planned vaginal delivery and whether emergency caesarean section or assisted vaginal delivery is associated with postnatal depression compared with spontaneous vaginal d...

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Delivery Practices of Traditional Birth Attendants in Dhaka Slums, Bangladesh

This paper describes associations among delivery-location, training of birth attendants, birthing practices, and early postpartum morbidity in women in slum areas of Dhaka, Bangladesh. During November 1993–May 1995, data on delivery-location, training of birth attendants, birthin...

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Effect of electrostatic charge, flow, delay and multiple actuations on the in vitro delivery of salbutamol from different small volume spacers for infants.

BACKGROUND: A study was undertaken to determine the influences of electrostatic charge, flow, delay, and multiple actuations on the in vitro delivery of salbutamol generated by a pressurised metered dose inhaler (pMDI) from small volume spacers used in infants. METHODS: Ten actua...

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Comparison of Domiciliary and Institutional Delivery-care Practices in Rural Rajasthan, India

A retrospective cross-sectional survey was conducted to assess key practices and costs relating to home- and institutional delivery care in rural Rajasthan, India. One block from each of two sample districts was covered (estimated population–279,132). Field investigators listed w...

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Peripartum Bacteremias Due to Leptotrichia amnionii and Sneathia sanguinegens, Rare Causes of Fever during and after Delivery

We report three cases of delivery and postpartum bacteremia due to unusual anaerobic bacteria in healthy young women. Leptotrichia amnionii bacteremia occurred during delivery in two mothers and was associated with fetal distress during labor. Conversely, Sneathia sanguinegens ba...

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Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells

The improvement of non-viral-based gene delivery systems is of prime importance for the future of gene and antisense therapies. We have previously described a peptide-based gene delivery system, MPG, derived from the fusion peptide domain of HIV-1 gp41 protein and the nuclear loc...

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Ruído em sala de parto : mensuração dos níveis e humanização da assistência / Noise in the delivery room : measurement of the levels and humanization of assistance

Objective: To assess the noise level in the delivery room during the birth process in two public hospitals in the state of Sao Paulo, one of them a teaching hospital (H1), considering the type of delivery. Methodology: This is exploratory, descriptive and observational. We used a...

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Alternative delivery systems in rural areas.

Alternative delivery systems, such as HMOs, PPOs, and primary care case-management programs, have a long history in rural America despite significant impediments to their development. However, little is known about the effect of these systems on rural communities and their medica...

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Can the delivery method influence lower urinary tract symptoms triggered by the first pregnancy?

INTRODUCTION AND OBJECTIVES: The increase of the intensity of urinary symptoms in late pregnancy and postpartum has been well documented by several authors, but their causes remain uncertain, partly because of its probable multifactor origin. There are also controversies whether ...

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Effects of various concentrations of diethylcarbamazine citrate applied as eye drops in ocular onchocerciasis, and the possibilities of improved therapy from continuous non-pulsed delivery.

Diethylcarbamazine was given as eye drops in varying concentrations in a half-log dilution series from 1.0 to 0.0001% to patients with ocular onchocerciasis. Migration of microfilariae into the cornea, followed by their straightening and disintegration, was observed with delivery...

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Outcome of subsequent pregnancy three years after previous operative delivery in the second stage of labour: cohort study

Objective To evaluate the reproductive outcome and the mode of delivery in subsequent pregnancies after instrumental vaginal delivery in theatre or caesarean section at full dilatation....

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Forceps delivery in modern obstetric practice

This review discusses the specific uses and potential advantages of forceps over other modes of delivery. To enable women to make an informed choice about mode of delivery, obstetricians need to be adequately trained and supervised in the use of forceps...

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Nanoparticulate drug delivery systems for the treatment of neglected tropical protozoan diseases

Abstract Neglected Tropical Diseases (NTDs) comprise of a group of seventeen infectious conditions endemic in many developing countries. Among these diseases are three of protozoan origin, namely leishmaniasis, Chagas disease, and African trypanosomiasis, caused by the parasites ...

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High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.

One limit to successful receptor-mediated gene delivery is the exit of the endocytosed material from the endosome. We demonstrate here the delivery of marker genes to tissue culture cells using a modification of the receptor-mediated gene delivery technique that exploits the endo...

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Liposome-based drug delivery in breast cancer treatment

Drug delivery systems can in principle provide enhanced efficacy and/or reduced toxicity for anticancer agents. Long circulating macromolecular carriers such as liposomes can exploit the 'enhanced permeability and retention' effect for preferential extravasation from tumor vessel...

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Dosagens de melatonina e de citocinas de acordo com a via de parto / Melatonin and cytokines concentrations in accordance with the mode of delivery

Objetive: To evaluate the profile of pro-inflammatory cytokines and the melatonin level in maternal and umbilical cord blood samples in accordance with the mode of delivery. Methods: Between March 2010 and September 2010, a prospective observational study was conducted at Univers...

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