Dermatan Sulfate
Mostrando 1-12 de 78 artigos, teses e dissertações.
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1. Urinary Glycosaminoglycan Electrophoresis With Optimized Keratan Sulfate Separation Using Peltier System for the Screening of Mucopolysaccharidoses
Abstract The purpose of this communication is to indicate a simple and rapid method with a small volume of urine sample to detect urine glycosaminoglycan (GAG) and serve as a screening procedure for mucopolysaccharidoses (MPSs). Total GAG measurement for patients with MPS disorders is considered to be the first step in diagnosis of those heterogeneous group
J. inborn errors metab. screen.. Publicado em: 19/06/2019
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2. Impact of Enzyme Replacement Therapy in a Patient Younger Than 2 Years Diagnosed With Maroteaux-Lamy Syndrome (MPS VI)
Abstract Introduction: Mucopolysaccharidosis type VI, also known as Maroteaux-Lamy syndrome (#OMIM 253200), is a rare autosomal recessive genetic disorder due to deficient activity of the enzyme N-acetylgalactosamine 4-sulfatase (arylsulfatase B) required for the breakdown of dermatan sulfate and chondroitin sulfate. Patient: Report of a female patient sta
J. inborn errors metab. screen.. Publicado em: 16/05/2019
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3. GLYCOSAMINOGLYCANS AND PROTEOGLYCANS IN PALMAR FASCIA OF PATIENTS WITH DUPUYTREN
Objective : To evaluate and compare the behavior of glycosaminoglycans (GAGs) in Dupuytren disease (DD). Methods : This is an experimental study with 23 patients diagnosed with DD. Tissue collected through fasciectomy with incision type Brunner or McCash were evaluated by electrophoresis for identification of GAGs. The quantification was carried out by imm
Acta ortop. bras.. Publicado em: 2016-04
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4. Evaluation of the metabolism of glycosaminoglycans in patients with interstitial cystis
Introduction: Painful bladder syndrome/interstitial cystitis (PBS/IC) pathogenesis is not fully known, but evidence shows that glycosaminoglycans (GAG) of bladder urothelium can participate in its genesis. The loss of these compounds facilitates the contact of urine compounds with deeper portions of bladder wall triggering an inflammatory process. We invest
Int. braz j urol.. Publicado em: 2014-01
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5. Avaliação do metabolismo de glicosaminoglicanos em pacientes portadores de cistite intersticial / Evaluation of the metabolism of glycosaminoglycans in patients with interstitial cystitis
Introduction: interstitial cystitis is a chronic disease of the lower urinary tract whose symptoms are: increased urinary frequency, nocturia, perineal or pelvic pain that worses with bladder filling and improves with urination. The pathogenesis is not fully known, but there is evidence that proteoglycans and glycosaminoglycans lining the bladder urothelium
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/12/2012
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6. Dermatan sulfate reduces monocyte chemoattractant protein 1 and TGF-β production, as well as macrophage recruitment and myofibroblast accumulation in mice with unilateral ureteral obstruction
Selectins play an essential role in most inflammatory reactions, mediating the initial leukocyte-rolling event on activated endothelium. Heparin and dermatan sulfate (DS) bind and block P- and L-selectin function in vitro. Recently, we reported that subcutaneous administration of DS inhibits colon inflammation in rats by reducing macrophage and T-cell recrui
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-07
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7. Efeito do dermatan sulfato na inflamação, trombose, formação de neointima e migração das celulas da medula ossea apos lesão arterial em camundongos / Effect of dermatan sulfate on inflammation, thrombosis, neointima formation and bone marrow cells migration after arterial injury in mice
O dermatan sulfato (DS) é um glicosaminoglicano que pode atuar como um agente antitrombótico, anticoagulante e anti-inflamatório. A aterosclerose é uma doença que acomete os vasos sanguíneos através da formação exacerbada de placas de gordura, interrompendo o fluxo de sangue. A intervenção cirúrgica mais utilizada nesses casos é a angioplastia,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/03/2010
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8. Glycosaminoglycan distribution in the rat uterine cervix during the estrous cycle
OBJECTIVE: To analyze the amount of glycosaminoglycans in the uterine cervix during each phase of the rat estrous cycle. DESIGN: Based on vaginal smears, forty female, regularly cycling rats were divided into four groups (n = 10 for each group): GI - proestrous, GII - estrous, GIII - metaestrous and GIV - diestrous. Animals were sacrificed at each phase of t
Clinics. Publicado em: 2010
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9. Proteoglicanos de estroma mamário e fibroadenoma humanos em diferentes condições hormonais. / Proteoglycans of human mammary stroma and fibroadenoma under different hormonal conditions.
Proteoglycans are important component of the extracellular matrix, which are involved in its organization and function, as well as in many biological processes. The aim of the present study was to investigate the changes that occur in proteoglycans of human fibroadenoma in comparison to proteoglycans of human normal breast tissue during the menstrual cycle.
Publicado em: 2009
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10. Characterization of musculoskeletal system in individuals with mucopolysaccharidosis type II : some kinectics features and functional consequences / Caracterização do sistema musculo-esqueletico em individuos com mucopolissacaridose Tipo II : alguns aspectos cineticos e consequencias funcionais
Mucopolysaccharidosis type II (MPS-II) is a rare lysosomal storage disorder caused by deficiency in the activity of the enzyme iduronate-2-sulphatase. This enzyme is responsible for the catabolism of two different glycosaminoglycans (GAGs), dermatan sulfate and heparan sulfate. Lysosomal accumulation of these glycosaminoglycan molecules results in cell, tiss
Publicado em: 2007
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11. Polissacarídeos sulfatados de interesse farmacológico no camarão litopenaeus schimitti
Sulfated Polysaccharides with unique chemical structures and important biological activities has been found in a diversity of sea invertebrates. For that, to exist a huger interest on the biotechnology field in the research theses sulfated compounds isolated from sea organisms. Despite the privileged brazilian position for these compounds attainment, there a
Publicado em: 2006
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12. Matriz extracelular de pericardio fibroso porcino : estudo morfologico e bioquimico / Extracellular matrix of porcine fibrous pericardium: morphological and biochemical study
Pericardial tissue has been used to construct bioprostheses employed in the repair different kinds of injuries. However, calcification and mechanical failure have been the main causes of limited durability of cardiac bioprostheses constructed with bovine pericardium. In the course of this work a study has been conducted on the porcine fibrous pericardium and
Publicado em: 2006