Diffuse Cutaneous Leishmaniasis
Mostrando 1-12 de 23 artigos, teses e dissertações.
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1. First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran
ABSTRACT Leishmaniasis is a worldwide tropical infectious disease caused by different species of intracellular protozoa parasites of the genus Leishmania . Herein, we report a 78-year-old man with unusual diffuse cutaneous leishmaniasis (DCL) who had a history of opium abuse and chronic obstructive pulmonary disease (COPD). He had multiple papular, crusted a
Rev. Inst. Med. trop. S. Paulo. Publicado em: 15/02/2018
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2. Chemokines and chemokine receptors expression in the lesions of patients with American cutaneous leishmaniasis
American cutaneous leishmaniasis (ACL) presents distinct active clinical forms with different grades of severity, known as localised (LCL), intermediate (ICL) and diffuse (DCL) cutaneous leishmaniasis. LCL and DCL are associated with a polarised T-helper (Th)1 and Th2 immune response, respectively, whereas ICL, or chronic cutaneous leishmaniasis, is associat
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-06
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3. Immune and inflammatory responses to Leishmania amazonensis isolated from different clinical forms of human leishmaniasis in CBA mice
Leishmania amazonensis causes different diseases depending on the host and parasitic virulence factors. In this study, CBA mice were infected with L. amazonensis isolates from patients with localized (Ba125), diffuse cutaneous (Ba276) or visceral leishmaniasis (Ba109). Mice infected with Ba125 and Ba276 progressed rapidly and lesions displayed an infiltrate
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-02
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4. LEISHMANIOSE TEGUMENTAR AMERICANA: uma abordagem farmacológica
The leishmaniasis (ACL) is a zoonotic disease whose etiologic agent, species of the genus Leishmania. And a disease of the skin and mucous membranes, primarily zoonotic involving a variety of wild and domestic mammals. Outbreaks of leishmaniasis occur by environmental changes due to deforestation, construction of dams, roads, mines, plant work areas, militar
Publicado em: 2009
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5. Characterization of the Leishmania (Leishmania) amazonensis genomic region containing the META 1 gene. / Caracterização da região genômica META 1 de Leishmania (Leishmania) amazonensis e comparação com a região ortóloga de L. (L.) major.
The characterization of coding sequences in the vicinity of the META 1 gene allowed the identification of some genes preferentially expressed in L. (L.) amazonensis infective stages. One of the identified transcripts presents a distinct pattern of expression with higher levels of mRNA in amastigotes. This gene was named LaLRR17 since it encodes a 72 kDa prot
Publicado em: 2008
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6. Limonóide de guarea kunthiana com potencial leishmanicida
Leishmaniasis is a neglected disease that affects many countries and is a severe public health problem. The number of cases has been increasing mainly due to Leishmania-HIV co-infection. The clinic forms include tegumentar (cutaneous, diffuse cutaneous and muco-cutaneous leishmaniasis), which affects skin and mucous membrane, and visceral (kala-azar), which
Publicado em: 2006
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7. Further observations on clinical, histopathological, and immunological features of borderline disseminated cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis
Leishmania (Leishmania) amazonensis has for some time been considered as the causative agent of two distinct forms of American cutaneous leishmaniasis (ACL): localized cutaneous leishmaniasis (LCL), and anergic diffuse cutaneous leishmaniasis (ADCL). Recently, a new intermediate form of disease, borderline disseminated cutaneous leishmaniasis (BDCL), was int
Memórias do Instituto Oswaldo Cruz. Publicado em: 2005-08
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8. AnÃlise in silico da HSP83 de Leishmania chagasi: implicaÃÃes para antigenicidade e evoluÃÃo
Protozoan parasites belonging to the genus Leishmania are transmitted between mammalian hosts by bloodsucking sand flies and are the etiological agents of the four clinical forms of leishmaniasis: the fatal visceral form, mucocutaneous leishmanasis, cutaneous leishmaniasis and the rare diffuse cutaneous leishmaniasis. Visceral leishmaniases is common in less
Publicado em: 2005
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9. Clinical and immunopathological spectrum of American cutaneous leishmaniasis with special reference to the disease in Amazonian Brazil: a review
The wide variety of Leishmania species responsible for human American cutaneous leishmaniasis combined with the immune mechanisms of the host results in a large spectrum of clinical, histopathological, and immunopathological manifestations. At the middle of this spectrum are the most frequent cases of localized cutaneous leishmaniasis (LCL) caused by members
Memórias do Instituto Oswaldo Cruz. Publicado em: 2004-05
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10. Therapy of Venezuelan patients with severe mucocutaneous or early lesions of diffuse cutaneous leishmaniasis with a vaccine containing pasteurized Leishmania promastigotes and bacillus Calmette-Guerin: preliminary report
Severe mucocutaneous (MCL) and diffuse (DCL) forms of American cutaneous leishmaniasis (ACL) are infrequent in Venezuela. Chemotherapy produces only transitory remission in DCL, and occasional treatment failures are observed in MCL. We have evaluated therapy with an experimental vaccine in patients with severe leishmaniasis. Four patients with MCL and 3 with
Memórias do Instituto Oswaldo Cruz. Publicado em: 2004-02
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11. Comparative study of American cutaneous leishmaniasis and diffuse cutaneous leishmaniasis in two strains of inbred mice.
Two Leishmania strains, AZV (isolated from a typical case of American cutaneous leishmaniasis) and AMP (from a case of diffuse cutaneous leishmaniasis), were studied in C57BL/6 and BALB/c mice. After infection with 10(4) amastigotes of either strain, C57BL/6 mice developed self-resolving lesions lasting 20 to 23 weeks and showed both delayed hypersensitivity
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12. Association of Leishmania heat shock protein 83 antigen and immunoglobulin G4 antibody titers in Brazilian patients with diffuse cutaneous leishmaniasis.
Diffuse cutaneous leishmaniasis (DCL) is characterized by the presence of numerous nonulcerated nodules and plaques containing large numbers of Leishmania amazonensis parasites and few lymphoid elements. The immune responses of DCL patients reflect severe antigen-specific T-cell deficiencies, while the antibody response to Leishmania antigens is often accent