Dipeptide
Mostrando 1-12 de 426 artigos, teses e dissertações.
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1. Solid-Phase Peptide Synthesis of Dipeptide (Histidine-β-Alanine) as a Chelating Agent by Using Trityl Chloride Resin, for Removal of Al3+, Cu2+, Hg2+ and Pb2+: Experimental and Theoretical Study
Solid-phase peptide synthesis of dipeptide (histidine-β-alanine) as a chelating agent examined by common N-9-fluorenylmethyloxycarbonyl-N-trityl-L-histidine and tert-butyloxycarbonyl-β-alanine-OH amino acid derivatives. Trityl chloride resin was used as a carrier resin. The molecular structure of the dipeptide was definite by using different methods such a
J. Braz. Chem. Soc.. Publicado em: 2016-10
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2. Glutamine dipeptide supplementation improves clinical responses in patients with diabetic foot syndrome
ABSTRACT The effect of glutamine dipeptide (GDP) supplementation in patients with diabetic foot syndrome was evaluated. A total of 22 patients took part in the study. GDP was supplied in 10 g sachets, and was dissolved in water immediately before use, with ingestion once a day, after lunch or after dinner (20 g/day) over a period of 30 days. Quantification o
Braz. J. Pharm. Sci.. Publicado em: 2016-09
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3. Synthesis of Biphenyl Tyrosine Via Cross-Coupling Suzuki-Miyaura Reaction Using Aryltrifluoroborate Salts
We reported a fast and easy method for obtaining biarylic units from tyrosine derivatives via Suzuki-Miyaura cross-coupling using a variety of substituted and unsubstituted potassium aryl- and heteroaryltrifluoroborate salts. The scope of the methodology was also extended to the formation of bis-tyrosine linked dipeptide bonds, leading to biologically intere
J. Braz. Chem. Soc.. Publicado em: 2015-04
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4. Preconditioning with L-alanyl-glutamine upon cerebral edema and hypocampus red neurons counting in rats subjected to brain ischemia /reperfusion injury
PURPOSE:To evaluate the effects of the dipeptide L-alanyl-glutamine (L-Ala-Gln) as a preconditioning agent to potentially promote reduction in the intensity of lesion or induction of resilience in rats subjected to global cerebral ischemia/reperfusion (I/R) injury.METHODS:Thirty-six male Wistar rats weighing 280-300g were randomly assigned to six groups (n=6
Acta Cir. Bras.. Publicado em: 2015-03
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5. Peptidoglycan from Staphylococcus aureus induces the overexpression of TRLs 1-8 mRNA in corneal fibroblasts, but its lipoteichoic acid and muramyl dipeptide only induced the overexpression of TLR5 or TRL9
Lipopolysaccharide induces TLR-1-8 mRNAs over-expression in corneal fibroblast. Analyzing if other TLR-ligands can do the same, we found that peptidoglycan does, but not muramyldipeptide, lipoteichoic acid and polyI:C. This suggests that the recognition of lipopolysaccharide and peptidoglycan is enough to alert these cells against microorganisms through the
Brazilian Journal of Microbiology. Publicado em: 2011-09
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6. Efeitos da l-alanil-glutamina na isquemia e reperfusÃo em cÃrebro de ratos wistar / Effects of l-alanyl-glutamine in ischemia and reperfusion in the brain of Wistar rats
The aim of this study was to investigate the effects of L-alanyl-glutamine (Ala-Gln) in ischemia and reperfusion in rat brain. We used 48 male rats, Wistar, with a mean age of 62 days and average weight of 276.38 g, divided into four groups: Sham 30 minutes ischemia, 90 minutes and Sham Ischemia / Reperfusion. We used a model of experimental global cerebral
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/09/2009
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7. Effects of supplementation with L-Glutamine and L-alanyl-Lglutamine upon parameters of muscle damage and inflammation in trained rats and submitted to intense exercise of swim / Efeito da suplementação com L-glutamina e L-alanil-L-glutamina sobre parâmetros de lesão muscular e de inflamação em ratos treinados e submetidos a exercício intenso de natação
Glutamine is the most abundant free amino acid found in plasma and muscle, and is utilized at high rates by many cells for maintenance and promotion of cell function. However, in some catabolic situations, like intense and prolonged or exhaustive physical exercise, a reduction in GLN availability is observed, fact that may impair the cell functions. Oral sup
Publicado em: 2008
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8. Dipeptide synthesis in biphasic medium: evaluating the use of commercial porcine pancreatic lipase preparations and the involvement of contaminant proteases
Sínteses bem sucedidas de dipeptídeos a partir de Ac-L-Tyr-OEt ou Z-L-X-OMe (X: Asp, Tyr, Phe, Arg, Lys ou Thr) e glicina amidada em meio reacional bifásico foram realizadas usando dois tipos de preparações comerciais de lipase pancreática suína (PPL) (bruta (cPPL) e purificada (pPPL)). Nas mesmas condições reacionais, a α-quimotripsina, protease p
Journal of the Brazilian Chemical Society. Publicado em: 2008
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9. Effects of L-alanyl-glutamine upon in vivo metabolites concentrations in rats subjected to hind limb ischemia followed by reperfusion / Efeitos da l-alanil-glutamina sobre as concentrações in vivo de metabólitos em ratos submetidos á isquemia-reperfusão do membro pélvico esquerdo
A study has been conducted to investigate the effects of L-alanyl-glutamine upon blood and tissue concentrations of metabolites (pyruvate, lactate, glucose, acetoacetato, 3-hydroxybutyrate, ketone bodies and ATP) in Wistar rats subjected to ischemia/reperfusion of hind limb. Ninety-six adult male rats were randomized in 4 groups and pre-treated with saline 2
Publicado em: 2005
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10. Dipeptide metabolites from the marine derived bacterium Streptomyces acrymicini
A investigação química do extrato bruto obtido a partir do meio de crescimento do actinomiceto Streptomyces acrimycini isolado de sedimentos marinhos levou ao isolamento de dois dipeptídeos: a 8-amino-[ 1,4] diazonano-2,5-diona (1) e leucil-4-hidroxiprolina (3). Os compostos foram isolados a partir do seu meio de crescimento por uma série de etapas crom
Journal of the Brazilian Chemical Society. Publicado em: 2004-06
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11. Adição de aliltricloroestananas a aldeidos dipeptidicos
The strategies developed for designing inhibitors active against HIV-1 protease involve the incorporation of a dipeptide isostere that resembles the tetrahedral intermediate for peptide bond hydrolysis. The hydroxy amino acid framework B, where the peptidic linkage of the sequence in A is replaced by a CH(OH)CH2 group, resulted as the core unit of potent inh
Publicado em: 2001
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12. Purificação e caracterização da insulina e de peptideos derivados do proglucagon e prossomatostatina isoladaos do, peixe frugivoro, pacu Piaractus mesopotamicus Holmberg, 1887 (Teleostei, Characidae Serrasalminae)
The fruit-eating teleost fish, the pacu Piaractus mesopotamicus Holmberg, 1887 (Characiformes, Characidae, Serrasalminae), similarly to tambaqui Colossoma macropomum, is classified with the carp and the catfish in the superorder Ostariophysi. The pacu and tambaqui have the pancreatic tissue exibiting both principal islet and small Brockmann bodies (Bbs). The
Publicado em: 1998