Dmpg
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Dispersões lipídicas de dimiristoil fosfatidilglicerol: um estudo termo-estrutural / Lipid dispersions of dymiristoyl phosphatidylglycerol: a thermo-structural study
Dispersions of the saturated anionic phospholipid dimyristoyl phosphatidyl glycerol (DMPG) have been extensively studied regarding their peculiar thermo-structural behavior. At low ionic strength, the gel-fluid transition is spread along nearly 17 ºC, displaying several thermal events in the calorimetric profile, quite different from the single sharp peak a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/12/2010
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2. Caracterização por espalhamento de luz de dispersões aquosas de agregados lipídicos aniônicos / Structural characterization of aqueous dispersions of the anionic phospholipid DMPG by light scattering
Neste trabalho caracterizamos dispersões aquosas de vesículas lipídicas por espalhamento de luz. Utilizamos os diferentes métodos da técnica: espalhamento de luz estático (SLS) e espalhamento de luz dinâmico (DLS) no estudo desses sistemas. No SLS a intensidade da luz espalhada foi coletada em vários ângulos de espalhamento para diferentes concentra
Publicado em: 2010
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3. Técnicas de fluorescência no monitoramento de membranas modelo / Fluorescence techniques to monitor model membranes
Apresentamos os resultados de estudos sobre a utilização de técnicas baseadas no fenômeno de fluorescência para a investigação de processos relacionados a membranas modelo. Nessa investigação, estão envolvidas medidas de propriedades espectrais de absorção e emissão de luz por cromóforos adequados, determinação xperimental de perfis de decaim
Publicado em: 2008
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4. Estratégias para prospecção e predição de peptídeos bioativos
Chapters one and two deal with the isolation and identification of bioactive peptides from the skin secretion of Phyllomedusa hypochondrialis. The first chapter demonstrates the use of protemic techniques, mainly mass spectrometry, for the study of bradykinin related peptides (BRPs) present in the amphibians secretion and freshly dissected skin fragments. Ei
Publicado em: 2007
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5. Caracterização estrutural de peptídeos melanotrópicos e suas interações com agregados anfifílicos: um estudo por fluorescência e ressonância paramagnética eletrônica / Structural caracterization of melanotropic peptides and their interaction with amphilic aggregates: a study by fluorescence and electron spin resonance
Neste trabalho são apresentados vários estudos com o peptídeo melanotrópico catiônico alfa-MSH (hormônio estimulador de melanócito) e análogos biologicamente mais ativos. Foram utilizadas as técnicas de fluorescência estática e resolvida no tempo, e RPE (ressonância paramagnética eletrônica). Com fluorescência, foi monitorado o aminoácido Trp
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/01/2002
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6. Comportamento térmico peculiar de dispersões aquosas do fosfolipídio aniônico DMPG / Peculiar thermal behavior of aqueous dispersions of the anionic phospholipid DMPG
Dispersões aquosas do fosfolipídio aniônico DMPG (dimiristoilfosfatidil glicerol) apresentam um comportamento térmico muito peculiar e interessante, principalmente em baixa força iônica. Neste trabalho, mostramos que o DMPG em baixa força iônica apresenta dois regimes com comportamentos térmicos muito distintos, dependendo da concentração lipídic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/04/2001
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7. Spin-label electron spin resonance studies on the interactions of lysine peptides with phospholipid membranes.
The interactions of lysine oligopeptides with dimyristoyl phosphatidylglycerol (DMPG) bilayer membranes were studied using spin-labeled lipids and electron spin resonance spectroscopy. Tetralysine and pentalysine were chosen as models for the basic amino acid clusters found in a variety of cytoplasmic membrane-associating proteins, and polylysine was chosen
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8. Binding of Pediocin PA-1 with Anionic Lipid Induces Model Membrane Destabilization
To obtain molecular insights into the action mode of antimicrobial activity of pediocin PA-1, the interactions between this bacteriocin and dimyristoylphosphatidylcholine (DMPC) or dimyristoylphosphatidylglycerol (DMPG) model membranes have been investigated in D2O at pD 6 by Fourier transform infrared spectroscopy. The interactions were monitored with respe
American Society for Microbiology.
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9. Roles of liposome composition and temperature in distribution of amphotericin B in serum lipoproteins.
The role of liposome composition and temperature in the distribution of amphotericin B (AmB) with serum lipoproteins and the role of particle charge in AmB transfer to serum lipoproteins were determined. Serum obtained from healthy volunteers was incubated with known concentrations of AmB or different liposomal formulations of AmB (1 to 100 micrograms/ml) at
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10. Crystal structure of a bifunctional aldolase–dehydrogenase: Sequestering a reactive and volatile intermediate
The crystal structure of the bifunctional enzyme 4-hydroxy-2-ketovalerate aldolase (DmpG)/acylating acetaldehyde dehydrogenase (DmpF), which is involved in the bacterial degradation of toxic aromatic compounds, has been determined by multiwavelength anomalous dispersion (MAD) techniques and refined to 1.7-Å resolution. Structures of the two polypeptides
National Academy of Sciences.
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11. Hisactophilin-mediated binding of actin to lipid lamellae: a neutron reflectivity study of protein membrane coupling.
The neutron reflectivity technique is applied to determine the adsorptive interaction of the 13.5-kDa actin-binding protein hisactophilin from Dictyostelium discoideum with lipid monolayers at a lateral pressure of 21 mN/m < or = pi < or = 25 mN/m at the air-water interface. We compare binding of natural hisactophilin exhibiting a myristic acid chain membran
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12. New approaches to the simulation of heat-capacity curves and phase diagrams of pseudobinary phospholipid mixtures.
A simulation program using least-squares minimization was developed to calculate and fit heat capacity (cp) curves to experimental thermograms of dilute aqueous dispersions of phospholipid mixtures determined by high-sensitivity differential scanning calorimetry. We analyzed cp curves and phase diagrams of the pseudobinary aqueous lipid systems 1,2-dimyristo