Dorsal Root Ganglia
Mostrando 1-12 de 221 artigos, teses e dissertações.
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1. Delay of neuropathic pain sensitization after application of dexamethasone-loaded implant in sciatic nerve-injured rats
Neuroimmune interactions underlying the development of pain sensitization in models of neuropathic pain have been widely studied. In this study, we evaluated the development of allodynia and its reduction associated with peripheral antineuroinflammatory effects induced by a dexamethasone-loaded biodegradable implant. Chronic constriction injury (CCI) of the
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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2. Expression of myo-inositol cotransporters in the sciatic nerve and dorsal root ganglia in experimental diabetes
The transport of myo-inositol is the main mechanism for the maintenance of its high intracellular levels. We aimed to measure the mRNA and protein levels of myo-inositol cotransporters in the sciatic nerve (SN) and dorsal root ganglia (DRG) during experimental diabetes. Streptozotocin-induced (STZ; 4, 8, and 12 weeks; 65 mg/kg; ip) diabetic rats (DB) and age
Braz J Med Biol Res. Publicado em: 03/06/2019
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3. Transcriptomic differential lncRNA expression is involved in neuropathic pain in rat dorsal root ganglion after spared sciatic nerve injury
Dorsal root ganglia (DRG) neurons regenerate spontaneously after traumatic or surgical injury. Long noncoding RNAs (lncRNAs) are involved in various biological regulation processes. Conditions of lncRNAs in DRG neuron injury deserve to be further investigated. Transcriptomic analysis was performed by high-throughput Illumina HiSeq2500 sequencing to profile t
Braz J Med Biol Res. Publicado em: 26/07/2018
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4. Carvacrol reduces neuronal excitability by inhibiting the channels to voltage-dependent sodium / Carvacrol reduz a excitabilidade neuronal pela inibição dos canais para sódio dependente de voltagem
O monoterpeno carvacrol está presente em muitos óleos essenciais de plantas e tem atraído atenção devido à sua grande variedade de atividades biológicas benéficas, especialmente atividade analgésica e o bloqueio da excitabilidade neuronal, no entanto, seu mecanismo de ação permanece desconhecido. O presente estudo teve como objetivo explorar os me
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/03/2012
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5. Mobilização neural em rato Wistar reverte comportamento e mudanças celulares que caracterizam a dor neuropática. / Neural mobilization reverses behavioral and cellular changes that characterize neuropathic pain in rats Wistar.
The Neural Mobilization technique is a noninvasive method that has proved clinically effective in reducing pain sensitivity and consequently in improving quality of life after neuropathic pain. The present study examined the effects of Neural Mobilization (MOB) on pain sensitivity induced by chronic constriction injury (CCI) in rats. The CCI was performed on
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/02/2012
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6. O ß-hidroxibutirato modifica os processos de ativação e inativação dos canais para sódio e potássio em corpos celulares de neurônios dos gânglios das raizes dorsais de ratos.
Under physiological conditions, the ketone bodies -hydroxybutyrate, acetoacetate and acetone are products of -oxidation of fatty acids that occurs in hepatocytes in response to hypoglycemia. This process occurs during fasting, high fat diets (such as the ketogenic diet, used in cases of drug-resistant epilepsy) and during diabetes mellitus in order to meet t
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/12/2011
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7. Papel da Miosina Va na neuritogênese de neurônios TrkA-positivos do glânglio da raiz dorsal. / The role of Myosin Va in the neuritogenesis of dorsal root ganglia TrkA-positive neurons.
Os gânglios da raiz dorsal (GRD) armazenam neurônios TrkA-positivos. A percepção e transmissão de estímulos por estes neurônios dependem de uma neuritogênese adequada. Miosina (MioVa) é expressa no tecido nervoso e está presente em neuritos, corpo celular e cone de crescimento. Caracterizamos o padrão de expressão de MioVa na neuritogênese de c�
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/10/2011
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8. Análise dos parâmetros eletrofisiológicos do nervo ciático e gânglio da raiz dorsal decorrentes de um período de imobilização da pata traseira direita de ratos diabéticos. / Analysis of the electrophysiological parameters of the sciatic nerve and dorsal root ganglia derived from a standstill of the right hind paw of diabetic rats.
Diariamente, milhares de pessoas passam por limitações físicas provisórias decorrentes da imobilização de alguma parte de seu corpo, podendo resultar numa alteração de sua função orgânica normal. Entretanto, esta situação poderá agravar-se quando o paciente for diabético, devido a alterações metabólicas e do sistema nervoso motor e sensitiv
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/05/2010
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9. Axotomy increases NADPH-diaphorase activity in the dorsal root ganglia and lumbar spinal cord of the turtle Trachemys dorbigni
Seven days after transection of the sciatic nerve NADPH-diaphorase activity increased in the small and medium neurons of the dorsal root ganglia of the turtle. However, this increase was observed only in medium neurons for up to 90 days. At this time a bilateral increase of NADPH-diaphorase staining was observed in all areas and neuronal types of the dorsal
Publicado em: 2010
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10. Cloning and expression analysis of the transcription factor Scratch2 during the chicken early embryogenesis. / Clonagem e análise da expressão do fator de transcrição Scratch2 durante a embriogênese inicial de galinha.
In invertebrates, the Scratch (Scrt) genes encode transcription factors that promote neurogenesis during development. The Scrt function in vertebrates is unknown, but in mice Scrt1 and Scrt2 are specifically expressed in post-mitotic neurons in the embryo and in the adult central nervous system. In this work, we have cloned the coding sequence of chicken Scr
Publicado em: 2009
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11. Investigação da ação neuroprotetora do fator neurotrofico ciliar (CNTF) conjugado com peptideo contendo dominio de translocação de proteina (PTD) / Investigation of neuroprotective action of ciliary neurotrophic factor (CNTF) fused to a protein transduction domain (PTD)
Ciliary neurotrophic factor (CNTF) is known as a neuroprotective agent on motoneurons after peripheral nerve section in neonatal rats and adult mice. However, side effects like weight loss and caquexia have limited its clinical use. A promising approach for the avoidance of such side effects is the fusion of a protein transduction domain (PTD) with CNTF. Pre
Publicado em: 2009
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12. Diversity among satellite glial cells in dorsal root ganglia of the rat
Peripheral glial cells consist of satellite, enteric glial, and Schwann cells. In dorsal root ganglia, besides pseudo-unipolar neurons, myelinated and nonmyelinated fibers, macrophages, and fibroblasts, satellite cells also constitute the resident components. Information on satellite cells is not abundant; however, they appear to provide mechanical and metab
Brazilian Journal of Medical and Biological Research. Publicado em: 31/10/2008