Dosage Form
Mostrando 1-12 de 196 artigos, teses e dissertações.
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1. Screening, diagnosis and management of hypothyroidism in pregnancy: Number 10 – October 2022
Key points Pregnancy places a metabolic overload on the maternal thyroid, especially in the first trimester, mainly because of the demand imposed by the conceptus. The fetal thyroid becomes functionally mature only around pregnancy week 20. Until then, the fetus depends on the transfer of maternal thyroid hormones (THs). Thyroid hormones are essential for
Revista Brasileira de Ginecologia e Obstetrícia. Publicado em: 2022
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2. STUDY OF SPECTROPHOTOMETRIC CHARACTERISTICS OF THE CHARGE TRANSFER COMPLEX OF TAURINE DRUG WITH 7,7,8,8-TETRACYANOQUINODIMETHANE
A new spectrophotometric method was developed for the determination of taurine using 7,7,8,8-tetracyanoquinodimethane (TCNQ). The method was based on the formation of charge transfer (CT) complex of this drug as n-electron donor with the π-acceptor TCNQ. TCNQ was found to react with taurine to produce a kind of yellow complex. The spectrum obtained for taur
Quím. Nova. Publicado em: 2020-09
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3. Biochemistry and Renal Function: Use of Inquiry-Based Teaching Sequences for Retrieval of Specific Concepts
RESUMO As propostas de ensino atuais envolvem estratégias de ensino que auxiliam e incentivam a construção do conhecimento, fazendo com que o aluno seja um participante ativo do processo de aprendizagem, e têm sido alvo de diversas pesquisas. Este artigo relata, aula a aula, uma sequência didática realizada com alunos em fase inicial de formação, apl
Rev. bras. educ. med.. Publicado em: 13/01/2020
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4. Outbreak of enzootic ataxia in goats and sheep in the state of Bahia
RESUMO: Objetivou-se com esse estudo descrever pela primeira vez os aspectos clínico-epidemiológicos, laboratoriais e patológicos de diferentes formas de ataxia enzoótica em cabritos e borregos no estado da Bahia, bem como propor um tratamento oral emergencial com sulfato de cobre de forma individualizada para neonatos. Foram estudados três surtos de at
Pesq. Vet. Bras.. Publicado em: 10/01/2020
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5. NEW APPLICATIONS FOR AMOXICILLIN DETERMINATION IN PURE FORM AND PHARMACEUTICALS BASED ON IODATE-IODIDE MIXTURE: TITRIMETRY AND SPECTROSCOPY STUDIES
Three simple methods are described for the determination of amoxicillin (AMX) in bulk drug and dosage forms using iodate-iodide mixture reagent. These methods employed the well-known analytical reaction between iodate-iodide mixture in the presence of acid solution. The iodide oxidized by iodate to iodine in an amount equivalent to the -COOH group present in
Quím. Nova. Publicado em: 2020-01
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6. Expression Analysis of Pyrenophora teres f. maculata-Responsive Loci in Hordeum vulgare
Abstract Pyrenophora teres f. maculata is the causal agent of barley spot form net blotch (SFNB), a major stubble-borne disease in many barley-growing areas worldwide. In plants, the Nucleotide-Binding Site-Leucine-Rich Repeat (NBS-LRR) gene family functions in immunity against a variety of pathogens and pests. From a pre-established set of NBS-type resistan
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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7. Application of quality by design approach in RP-HPLC method development for simultaneous estimation of saxagliptin and dapagliflozin in tablet dosage form
A simple, sensitive, precise, accurate and robust high performance liquid chromatographic method has been developed for simultaneous estimation of saxagliptin (SAXA) and dapagliflozin (DAPA) in pharmaceutical formulation. Design of experiments (DoE) was applied for multivariate optimization of the experimental conditions of RP-HPLC method. Risk assessment wa
Braz. J. Pharm. Sci.. Publicado em: 24/10/2019
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8. CARE GIVEN TO NEWBORNS FED BY GASTRIC TUBE: CONCEPTS AND PRACTICES
RESUMO Objetivo: descrever as condutas relacionadas a cuidados na alimentação através de sonda gástrica em recém-nascidos internados na Unidade de Terapia Intensiva Neonatal, a partir de artigos científicos publicados nos últimos cinco anos. Método: desenvolveu-se uma revisão integrativa de literatura nas bases de dados: MEDLINE, LILACS, SciELO,
Texto contexto - enferm.. Publicado em: 12/08/2019
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9. A NEW VALIDATED METHOD FOR DETERMINATION OF ROFLUMILAST IN TABLET BY CZE-UV
This paper reports a new and validated capillary electrophoresis method to determine Roflumilast (RFL) with an internal standard in tablet. The separation was made on an uncoated fused-silica capillary column 50 cm effective length and 75 µm i.d. 20 mmol L-1 of Na2B4O7 buffer including 15% (v/v) methanol (pH=9.5) was used as background electrolyte. A potent
Quím. Nova. Publicado em: 18/07/2019
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10. Developed and validated stability indicating HPLC method for the determination of epirubicin in bulk drug, marketed injection and polymeric nanoparticles
Present work is aimed to develop a simple, sensitive, robust and reliable HPLC method for routine quality control of epirubicin (EPI) in bulk drug, marketed injections and polymeric nanoparticles. Separation was carried out by C18 column. Isocratic elution was carried out using mobile phase A: 0.16% o-phosphoric acid solution, B: acetonitrile and methanol mi
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
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11. Challenges to improve the biopharmaceutical properties of poorly water-soluble drugs and the application of the solid dispersion technology
ABSTRACT The oral solid dosage forms are extremely relevant to drug therapy and responsible for much of the pharmaceutical industry turnover worldwide. However, the development of medicines in solid form involves significant challenges, including obtaining formulations with appropriate bioavailability for low aqueous solubility drugs (classes II and IV of th
Matéria (Rio J.). Publicado em: 06/12/2018
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12. Development of self-nanoemulsifying tablet (SNET) for bioavailability enhancement of sertraline
Abstract The purpose of the study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form. Self-nanoemulsifying drug delivery system (SNEDDS) was prepared to enhance the solubility and thus oral bioavailability of sertraline. Aqueous titration method was used to prepare the liquid SNEDDS; ternary
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018