Doxorrubicin
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Estudo preliminar da farmacocinética da doxorrubicina e avaliação do ajuste de dose em mulheres com cancêr de mama / Preliminary investigation of the pharmacokinetics of doxorubicin and evaluation of dose adjustment in women with breast cancer
Objetivos: Simular um ajuste de dose em pacientes com sobrepeso e com obesidade que utilizam a doxorrubicina (DOX), que proporcione curvas de concentração plasmática e concentrações máximas (Cmáx) semelhantes às de pacientes com peso normal. Metodologia: Determinou-se as concentrações plasmáticas de DOX em pacientes com câncer de mama após a adm
Publicado em: 2010
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2. Efeito protetor do chá verde (Camellia sinensis) contra a ação genotóxica da doxorrubicina, em células somáticas de Drosophila melanogaster
The green tea is considered a functional food with antioxidant activity, and this delays the process of old age and helps in the prevention of chronicle and degenerative diseases, such as cancer and heart affections. Of catechins, present in green tea, may is extremely important in the inactivation of free radicals, which provoke damages to the DNA molecules
Publicado em: 2008
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3. Clinical study of the effect of doxorubicin administration in feline injection-site sarcoma / Estudo clínico sobre o efeito da administração de doxorrubicina no sarcoma de aplicação em felino
The feline injection-site sarcoma (FISS) becomes a big challenge for Veterinary Medicine nowadays. Its first description was in 1991, and since then several studies have been done aiming to find out the FISS´s etiology and etiopathology. The object of this project is to demonstrate the effectiveness of chemotherapy protocols in FISS´s treatment in two grou
Publicado em: 2006
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4. Expressão de PRSS11, MTSS1, CLPTM1, SMYD2, NOTCH1 e RPL37A em fatias de carcinoma de mama de cadelas e correlação com resposta à doxorrubicina in vitro / Expression of PRSS11, MTSS1, CLPTM1, SMYD2, NOTCH1 and RPL37A in slices of bitch mammary cancer and correlation with response to exposure doxorubicin in vitro
Mammary gland tumors are the most common neoplasias of bitches and doxorubicin is one the mainstay drugs used in their treatment. Neoadjuvant chemotherapy with doxorubicin not only reduces the primary tumor as well as allows an in vivo evaluation of tumor response. Predictive markers of response, if identified, might allow a tailored treatment of each patien
Publicado em: 2006