Dpag
Mostrando 1-12 de 16 artigos, teses e dissertações.
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1. Envolvimento de mecanismos glutamatérgicos da substância cinzenta periaquedutal dorsal e do hipotálamo medial no medo condicionado à luz / Involvement of glutamatergic mechanisms of the dorsal periaqueductal gray matter and medial hypothalamus in conditioned fear to the light
A substância cinzenta periaquedutal dorsal (dPAG) e o hipotálamo medial (MH) são duas estruturas encefálicas que estão envolvidas na elaboração de estados aversivos e expressão de respostas defensivas. A estimulação elétrica da dPAG ou do MH produz uma série de respostas comportamentais que se assemelham às respostas defensivas induzidas pela pr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/09/2012
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2. Involvement of NK-1 receptors of the basolateral and central nuclei of the amygdala in the defensive behavior of rats / Participação dos receptores NK-1 dos núcleos basolateral e central da amígdala no comportamento defensivo de ratos
A substantial body of evidence obtained in the last decade demonstrated that the Substance P (SP) is an important mediator of the affective and emotional behaviors. SP is a pro-aversive compound when microinjected within the dorsal periaqueductal gray (dPAG). These effects are mediated by the type 1 neurokininergic receptors (NK-1), since the defensive behav
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/06/2012
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3. DPAG ELETRICAL STIMULATION EFFECT IN DEFENSE BEHAVIORS: IN THE ROSTRAL ANTERIOR CINGULATED CORTEX PARTICIPATION AND IN CARIOCA HIGH-FREEZING AND LOW-FREEZING BREEDING LINES / EFEITO DA ESTIMULAÇÃO ELÉTRICA DA MCPD EM COMPORTAMENTOS DE DEFESA: PARTICIPAÇÃO DO CÓRTEX CINGULADO ANTERIOR ROSTRAL E NAS LINHAGENS CARIOCA ALTO E BAIXO CONGELAMENTO
A matéria cinzenta periaquedutal dorsal (MCPD) é associada com comportamento defensivo e ataques de pânico em humanos. Estimulações elétricas da MCPD induzem a um repertório de defesa: o congelamento pré fuga, reação de fuga e congelamento pós fuga. Evidências já apresentadas suportam a hipótese que enquanto o congelamento pré fuga seria um mo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/04/2012
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4. ROLE OF DORSAL AND VENTRAL HIPPOCAMPUS ON CONDITIONED AND UNCONDITIONED FEAR ELICITED BY DORSAL PERIAQUEDUCTAL GREY MATTER ELECTRICAL STIMULATION IN RATS / PARTICIPAÇÃO DO HIPOCAMPO DORSAL E VENTRAL NAS REAÇÕES DE DEFESA PRODUZIDAS PELO CONDICIONAMENTO CONTEXTUAL DE MEDO E PELA ESTIMULAÇÃO ELÉTRICA DA MATÉRIA CINZENTA PERIAQUEDUTAL DORSAL
This study investigates the role of the hippocampus in both unconditioned and conditioned defense behavior by examining the effects of pre-training electrolytic lesions to the dorsal and ventral hippocampus in male rats exposed to two types of threat stimuli: electrical stimulation of the DPAG and footshock. Our results indicate that ventral and dorsal lesio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2012
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5. Dorsal periaqueductal gray stimulation facilitates anxiety-, but not panic-related, defensive responses in rats tested in the elevated T-maze
The escape response to electrical or chemical stimulation of the dorsal periaqueductal gray matter (DPAG) has been associated with panic attacks. In order to explore the validity of the DPAG stimulation model for the study of panic disorder, we determined if the aversive consequences of the electrical or chemical stimulation of this midbrain area can be dete
Braz J Med Biol Res. Publicado em: 2012-11
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6. Involvement of midbrain tectum neurokinin-mediated mechanisms in fear and anxiety
Electrical stimulation of midbrain tectum structures, particularly the dorsal periaqueductal gray (dPAG) and inferior colliculus (IC), produces defensive responses, such as freezing and escape behavior. Freezing also ensues after termination of dPAG stimulation (post-stimulation freezing). These defensive reaction responses are critically mediated by γ-amin
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-04
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7. Contrasting effects of nitric oxide and corticotropin- releasing factor within the dorsal periaqueductal gray on defensive behavior and nociception in mice
The anxiogenic and antinociceptive effects produced by glutamate N-methyl-D-aspartate receptor activation within the dorsal periaqueductal gray (dPAG) matter have been related to nitric oxide (NO) production, since injection of NO synthase (NOS) inhibitors reverses these effects. dPAG corticotropin-releasing factor receptor (CRFr) activation also induces anx
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-04
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8. Panic-like behaviors in Carioca High-and Low-conditioned Freezing rats
Panic disorder involves both recurrent unexpected panic attacks and persistent concern about having additional attacks. Electrical stimulation of the dorsal periaqueductal gray (dPAG) is an animal model of both panic attack and panic disorder, whereas contextual fear conditioning represents a model of anticipatory anxiety. Previous research indicated that an
Psychology & Neuroscience. Publicado em: 2011
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9. Gabaergic mechanisms of anterior and ventromedial hypothalamic nuclei in the expression of freezing in response to a light-conditioned stimulus
The amygdala, dorsal periaqueductal gray (dPAG), and medial hypothalamus have long been recognized to comprise a neural system responsible for the generation and elaboration of unconditioned fear in the brain. This neural substrate is well known to be under tonic inhibitory control exerted by γ-aminobutyric acid (GABA) mechanisms. Some evidence also suggest
Psychology & Neuroscience. Publicado em: 2011
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10. Leishmaniose Visceral Canina: Doença de Caráter Fibrosante
Este trabalho teve como objetivo estudar as alterações da matriz extracelular com ênfase à colagenogênese no fígado, baço, linfonodos cervicais, pulmões e rins de cães naturalmente infectados com Leishmania (Leishmania) chagasi considerando aspectos clínicos, anátomo-patológicos e parasitológicos. Para esse estudo foram utilizados materiais pert
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/02/2010
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11. Role of nitric oxide in the periaqueductal gray in defensive behavior in mice: influence of prior local N-methyl-D-aspartate receptor activation and aversive condition
Glutamate N-methyl-D-aspartate (NMDA) receptor activation within the dorsal column of the periaqueductal gray (dPAG) leads to antinociceptive, autonomic, and behavioral responses characterized as the fear reaction. Activation of NMDA receptors in the brain increases nitric oxide (NO) synthesis, and NO has been proposed to be a mediator of the aversive action
Psychology & Neuroscience. Publicado em: 2010-06
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12. Effects of contextual fear conditioning and pentylenetetrazol on panic-like reactions induced by dorsal periaqueductal gray stimulation with N-methyl-D-aspartate
Electrical or chemical stimulation of the dorsal periaqueductal gray (DPAG) has been accepted as an animal model of panic attacks. This study investigates the influence of anticipatory anxiety in the occurrence of panic-like behavior induced by N-methyl-D-aspartate (NMDA) microinjection into the DPAG of rats. Behavioral (i.e., contextual fear conditioning) a
Psychology & Neuroscience. Publicado em: 2010-06