Drug Induced Gingival Overgrowth
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Analise dos efeitos e dos mecanismos de ação do fator de crescimento transformante- beta 1, interferon gama e iclosporina A na transdiferenciação dos fibroblastos gengivais em miofibroblastos / Effects of transforming growth factor- beta 1, interferon gamma and cyclosporin A on transdifferentiation of gingival fibroblasts in myofibroblasts
Myofibroblasts are the main cellular type involved in extracellular matrix deposition in fibrotic diseases. Relatively little is known about the underlying mechanisms that regulate myofibroblast emergence (transdifferentiation), however the regulatory cytokine transforming growth factor-beta 1 (TGF- beta 1) has been traditionally considered an inducer of the
Publicado em: 2007
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2. In situ hibridization for Epstein-Barr virus (EBV) and Human Papiloma virus in drug-induced gingival overgrowth in renal transplantation patients / Identificação do vírus Epstein-Barr (EBV) e do papiloma vírus humano (HPV) através da técnica de hibridização in situ em hiperplasias gengivais medicamentosas de pacientes transplantados renais
A fim de prevenir a rejeição do órgão transplantado pelo hospedeiro, se faz necessário o uso de drogas imunossupressoras, como a ciclosporina, que pode levar ao aparecimento de efeitos colaterais como hipertensão arterial, nefrotoxicidade, hepatotoxicidade, e hiperplasia gengival medicamentosa (HGM), que pode ser potencializada se bloqueadores de canal
Publicado em: 2007
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3. Análise microscópica e da imunoexpressão dos marcadores de proliferação celular Ki-67 e Ciclina B1 no epitélio gengival de pacientes sob terapia com nifedipina
Drug induced gingival overgrowth (DIGO) is an adverse effect associated with the chronic use of three main drugs: phenytoin, an anticonvulsant, cyclosporin, an immunosuppressant drug and the pharmacological agents known as calcium channel blockers (CCB). Nifedipine is a calcium channel blocker, which because of its strong vessel dilating action has become wi
Publicado em: 2006
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4. Análise microscópica e da imunoexpressão dos marcadores de proliferação celular Ki-67 e Ciclina B1 no epitélio gengival de pacientes sob terapia com nifedipina
Drug induced gingival overgrowth (DIGO) is an adverse effect associated with the chronic use of three main drugs: phenytoin, an anticonvulsant, cyclosporin, an immunosuppressant drug and the pharmacological agents known as calcium channel blockers (CCB). Nifedipine is a calcium channel blocker, which because of its strong vessel dilating action has become wi
Publicado em: 2006
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5. Diphenylhydantoin (dilantin) gingival hyperplasia: drug-induced abnormality of connective tissue.
Various degrees of gingival overgrowth may occur in individuals taking diphenylhydantoin, a drug used widely in the treatment of epilepsy. The tissue overgrowth is made up predominantly of collagen, and may therefore be a useful model for analysis of fibrosis and some other connective tissue abnormalities. Fibroblasts derived from the overgrown tissue exhibi