Electronegative Ldl
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Oxidized and electronegative low-density lipoprotein as potential biomarkers of cardiovascular risk in obese adolescents
OBJECTIVES: To evaluate biomarkers associated with early cardiometabolic risk in obese adolescents. METHODS: This cross-sectional study included 137 adolescents of both sexes aged 10 to 19 years divided into a normal weight group (NW) (n=69) and an obese group (OB) (n=68). RESULTS: As expected, obesity showed positive associations with homeostatic model a
Clinics. Publicado em: 18/10/2018
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2. Papel da lipoproteína de baixa densidade eletronegativa, da proteína transportadora de éster de colesterol e da resistência à insulina no risco cardiometabólico de adolescentes obesos / Role of the electronegative low-density lipoprotein, cholesteryl ester transfer protein and insulin resistance in the cardiometabolic risk of the adolescents
Introdução: A obesidade é um importante problema de Saúde Pública e, segundo a Organização Mundial da Saúde, representa uma epidemia global. É considerada uma doença crônica, multifatorial, que depende não só de fatores genéticos e fisiopatológicos, mas também de variáveis culturais, sociais e psicológicas associadas à quantidade e a quali
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/10/2011
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3. Desenvolvimento de imunoensaios e biossensores para determinação de LDL eletronegativa / Development of immunoassays and biosensors for electronegative LDL quantification
A lipoproteína de baixa densidade eletronegativa (LDL-) é um importante antígeno envolvido na patogênese da aterosclerose. A LDL(-) provoca resposta inflamatória e imunológica, levando à produção de autoanticorpos anti-LDL(-) e a formação subsequente de imunocomplexos (IC-LDL-), os quais também contribuem com o processo aterosclerótico. Diante d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/08/2010
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4. Expressão de fragmentos variáveis de cadeia simples anti-LDL eletronegativa (scFv) em Pichia pastoris e seu efeito sobre a formação de células espumosas / Expression of anti-electronegative LDL single-chain fragment variable (scFv) in Pichia pastoris and its effect on foam cells formation
Os produtos de modificação de lipoproteínas de baixa densidade (LDL) como a subfração eletronegativa [LDL(-)] desempenham um importante papel na progressão da aterosclerose. O acúmulo massivo de LDL modificada captada por macrófagos resulta em células espumosas que liberam mediadores inflamatórios e contribuem para a aterogênese. O scFv (single ch
Publicado em: 2010
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5. Hyperglycemia during acute myocardial infarction: pathophysiology correlations / Hiperglicemia no infarto agudo do miocárdio: correlações fisiopatológicas
Introduction- Hyperglycemia (HG) is an important prognostic factor in acute myocardial infarction (AMI). However, the pathophysiology is poorly understood. So we proposed a simultaneous correlation between glycemia and biochemical markers of stress, glucose and lipid metabolism, coagulation and inflammation system. Methods- Eighty AMI patients were included
Publicado em: 2009
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6. Antibodies against electronegative LDL inhibit atherosclerosis in LDLr-/- mice
In order to determine the effect of antibodies against electronegative low-density lipoprotein LDL(-) on atherogenesis, five groups of LDL low receptor-deficient (LDLr-/-) mice (6 per group) were immunized with the following antibodies (100 µg each): mouse anti-LDL(-) monoclonal IgG2b, rabbit anti-LDL(-) polyclonal IgG or its Fab fragments and mouse irrelev
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-12
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7. Influência do sobrepeso e da obesidade em adolescentes na geração de lipoproteínas de baixa densidade eletronegativa (LDL) / Influence of overweight and obesity in adolescents in generation of electronegative low density lpoproteins
Introduction: Some evidence suggests that the prevalence of overweight and obesity has significantly increased in the pediatric population. Obesity represents a chronic and inflammatory disease, where oxidative modification is associated. Many factors modulate the oxidative susceptibility of LDL and produces the LDL- and diet is considered very important in
Publicado em: 2008
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8. Effects of rosuvastatin on electronegative LDL as characterized by capillary isotachophoresis: the ROSARY Study
Electronegative LDL, a charge-modified LDL (cm-LDL) subfraction that is more negatively charged than normal LDL, has been shown to be inflammatory. We previously showed that pravastatin and simvastatin reduced the electronegative LDL subfraction, fast-migrating LDL (fLDL), as analyzed by capillary isotachophoresis (cITP). The present study examined the effec
The American Society for Biochemistry and Molecular Biology.
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9. Generation in Human Plasma of Misfolded, Aggregation-Prone Electronegative Low Density Lipoprotein
Human plasma contains small amounts of a low density lipoprotein in which apoprotein is misfolded. Originally identified and isolated by means of anion-exchange chromatography, this component was subsequently described as electronegative low density lipoprotein (LDL)(−), with increased concentrations associated with elevated cardiovascular disease risk. It
The Biophysical Society.