Elevated Plus Maze Epm Ott
Mostrando 1-3 de 3 artigos, teses e dissertações.
-
1. Efeito ansiolítico do ondansetron, antagonista dos receptores 5-HT3, injetado na amídala de camundongos submetidos à exposição e reexposição no labirinto em cruz elevado
Against of stimuli that are dangerous, animals manifest defense reactions that cause fear and anxiety. These stimuli activate the serotonergic system, which sends projections to structures involved in defense mechanisms such as the septum, hypothalamus, hippocampus, amygdala and periaqueductal gray modulates the behavioral changes that can be characterized a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2011
-
2. Hormonal and cognitive factors associated with the exploratory behavior of rats submitted to repeated sessions of the elevated plus-maze
Naive rats submitted to the elevated plus-maze (EPM) display a characteristic increase in open arm exploration and reduced risk assessment behaviors (RABs) after the administration of anxiolytic drugs. Upon re-exposure to the maze, however, the traditional measures of the EPM become resistant to these drugs. This intriguing phenomenon was initially observed
Psychology & Neuroscience. Publicado em: 2010-06
-
3. "Modulação por mecanismos serotoninérgicos do comportamento exploratório de ratos submetidos ao teste e reteste no labirinto em cruz elevado" / "Modulation by serotonergic mechanisms of the exploratory behavior of rats submitted to the test and retest in the elevated plus-maze"
The elevated plus-maze (EPM) is currently one of the most used test of anxiety. An intriguing feature of this model is the abolition of the anxiolytic effect of benzodiazepines by a single previous experience with the maze. This phenomenon, termed one-trial tolerance (OTT), has received considerable attention and among the several hypotheses suggested to exp
Publicado em: 2006