Enac
Mostrando 1-12 de 67 artigos, teses e dissertações.
-
1. Estudo da ação do veneno de Tityus serrulatus sobre a expressão de transportadores de sódio e água em epitélio alveolar de rato / Effect of Tityus serrulatus venom on sodium and water trasporters in rat alveolar epithelium
Acidentes escorpiônicos podem evoluir com edema pulmonar de origem cardiogênica e não cardiogênica. O clearance de edema pulmonar está relacionado principalmente ao transporte ativo de sódio do espaço alveolar para o interstício. O objetivo deste trabalho foi avaliar os efeitos do veneno de Tityus serrulatus e da dexametasona sobre a expressão dos t
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/08/2012
-
2. Comparison of different ultrasonic vibration modes for post removal
Este estudo in vitro comparou diferentes modos de vibração ultra-sônica na remoção de pinos intra-radiculares fundidos. As coroas de 24 caninos superiores foram removidas, as raízes foram incluídas em blocos de resina acrílica e tratadas endodonticamente. Os espaços para os pinos intra-radiculares foram preparados e depois moldados com resina acríl
Brazilian Dental Journal. Publicado em: 2012
-
3. Efeitos da N-acetilcisteína na função pulmonar e renal em ratos com sepse sob ventilação mecânica invasiva / Effects of N-acetylcysteine on pulmonary and renal function on septic rats in invasive mechanical ventilation
Introdução: A sepse pode causar alterações renais e pulmonares. Nos casos mais graves, a ventilação mecânica invasiva (VMI) torna-se necessária para melhorar as trocas gasosas e fornecer adequado oxigênio as células. Entretanto, seu uso está associado com piora da função renal. O estresse oxidativo está aumentado na sepse e relaciona-se com o a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/06/2011
-
4. Influence of luting agents on time required for cast post removal by ultrasound: an in vitro study
OBJECTIVE: This in vitro study evaluated the influence of luting agents on ultrasonic vibration time for intraradicular cast post removal. MATERIAL AND METHODS: After endodontic treatment, 30 roots of extracted human canines were embedded in resin cylinders. The post-holes were prepared at 10 mm depth and their impressions were taken using autopolymerizing a
Journal of Applied Oral Science. Publicado em: 2009-06
-
5. Comparison of the time required for removal of intraradicular cast posts using two Brazilian ultrasound devices
The aim of this in vitro study was to compare the time required for removal of intraradicular cast posts cemented with zinc phosphate (ZF) or glass ionomer cement (GIC), using two Brazilian ultrasound devices (BUD). Seventy two human inferior premolars with single root canals were sectioned transversally at the cementoenamel junction. In each specimen, the r
Brazilian Oral Research. Publicado em: 2009-03
-
6. Resistência aos mineralocorticóides: pseudo-hipoaldosteronismo tipo 1
Pseudo-hipoaldosteronismo tipo 1 (PHA1) é uma doença genética rara, caracterizada por vômitos, desidratação, baixo ganho pôndero-estatural e perda urinária de sal no período neonatal. Indivíduos afetados apresentam hiponatremia, hipercalemia, aumento da atividade de renina plasmática e concentrações muito elevadas de aldosterona plasmática, sec
Arquivos Brasileiros de Endocrinologia & Metabologia. Publicado em: 2007-04
-
7. The Cystic Fibrosis Transmembrane Regulator (CFTR) in the kidney
The cystic fibrosis transmembrane regulator (CFTR) is a Cl- channel. Mutations of this transporter lead to a defect of chloride secretion by epithelial cells causing the Cystic Fibrosis disease (CF). In spite of the high expression of CFTR in the kidney, patients with CF do not show major renal dysfunction, but it is known that both the urinary excretion of
Anais da Academia Brasileira de Ciências. Publicado em: 2000-09
-
8. Extracellular Chloride Regulates the Epithelial Sodium Channel*
The extracellular domain of the epithelial sodium channel ENaC is exposed to a wide range of Cl− concentrations in the kidney and in other epithelia. We tested whether Cl− alters ENaC activity. In Xenopus oocytes expressing human ENaC, replacement of Cl− with SO42−, H2PO4−, or SCN− produced a large increase in ENaC current, indicating that extrac
American Society for Biochemistry and Molecular Biology.
-
9. Biphasic regulation of ENaC by TGF-α and EGF in renal epithelial cells
The epithelial sodium channel (ENaC) is regulated by epidermal growth factor (EGF). We investigate whether ENaC is regulated by another EGF receptor (EGFR) ligand, transforming growth factor-α (TGF-α). We show that chronic (24 h) treatment with TGF-α inhibits ENaC in Xenopus laevis kidney cells 20 times more strongly than EGF. By using single-channel meas
American Physiological Society.
-
10. Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome
Liddle's syndrome is an inherited form of hypertension linked to mutations in the epithelial Na+ channel (ENaC). ENaC is composed of three subunits (α, β, γ), each containing a COOH-terminal PY motif (xPPxY). Mutations causing Liddle's syndrome alter or delete the PY motifs of β- or γ-ENaC. We recently demonstrated that the ubiquitin–protein ligase Ne
American Society for Clinical Investigation.
-
11. The Activity of the Epithelial Sodium Channels Is Regulated by Caveolin-1 via a Nedd4-2-dependent Mechanism*
It has recently been shown that the epithelial Na+ channel (ENaC) is compartmentalized in caveolin-rich lipid rafts and that pharmacological depletion of membrane cholesterol, which disrupts lipid raft formation, decreases the activity of ENaC. Here we show, for the first time, that a signature protein of caveolae, caveolin-1 (Cav-1), down-regulates the
American Society for Biochemistry and Molecular Biology.
-
12. The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl– concentration
Activation of the CFTR Cl– channel inhibits epithelial Na+ channels (ENaC), according to studies on epithelial cells and overexpressing recombinant cells. Here we demonstrate that ENaC is inhibited during stimulation of the cystic fibrosis transmembrance conductance regulator (CFTR) in Xenopus oocytes, independent of the experimental set-up and the magnitu
Oxford University Press.