Endocrine Neoplasms
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)
Resumo A trombocitose é o aumento do número de plaquetas por microlitro (µL) de sangue e contagens maiores que 1.000.000/µL podem estar associadas a sinais clínicos de sangramento ou trombose. Estudos anteriores sobre as causas subjacentes da trombocitose tem despertado o interesse quanto a sua importância clínica em cães. O presente estudo teve como
Ciênc. anim. bras.. Publicado em: 18/07/2019
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2. Follicular thyroid carcinoma metastatic to skin: a small papule and a big diagnostic change
Abstract: Cutaneous metastases are uncommon in daily practice, although very important, since they may be the first manifestation of an undiscovered primary neoplasm or the first indication of recurrence. Cutaneous metastases from the breast are the most frequent in women and cutaneous metastases from the lung are the most frequent in men. Thyroid carcinoma,
An. Bras. Dermatol.. Publicado em: 2019-02
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3. Temozolomide in aggressive pituitary adenomas and carcinomas
Temozolomide is an alkylating agent used in the treatment of gliomas and, more recently, aggressive pituitary adenomas and carcinomas. Temozolomide methylates DNA and, thereby, has antitumor effects. O6-methylguanine-DNA methyltransferase, a DNA repair enzyme, removes the alkylating adducts that are induced by temozolomide, thereby counteracting its effects.
Clinics. Publicado em: 2012
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4. Clinical and genetic aspects of familial isolated pituitary adenomas
Pituitary adenomas represent a group of functionally diverse neoplasms with relatively high prevalence in the general population. Most occur sporadically, but inherited genetic predisposing factors are increasingly recognized. Familial isolated pituitary adenoma is a recently defined clinical entity, and is characterized by hereditary presentation of pituita
Clinics. Publicado em: 2012
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5. Analise da expressão do gene BRAF e suas possiveis implicações diagnosticas e prognosticas para pacientes portadores de carcinoma papilifero da tireoide / BRAF expression may help identify malignant nodules and define outcomes in papillary thyroid cancer patients
Background: Thyroid cancer is the most common endocrine malignancy, corresponding to 1% of all human neoplasms. Thyroid nodules are very frequent, mainly in women over 60 years. The relationship of BRAF gene with papillary thyroid tumorigenesis is well recognized in the literature. Its BRAFV600E mutation has been related to tumor aggressiveness and patients�
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2009
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6. Estudo da expressão dos receptores do peptídeo insulinotrópico dependente de glicose (GIPR) e do hormônio luteinizante (LHCGR) em tumores e hiperplasias do córtex adrenal / Expression Study of Glucose-dependent insulinotropic peptide receptor (GIPR) and luteinizing hormone receptor (LHCGR) in adrenocortical tumors and hyperplasia
Introduction: The glucose- dependent insulinotropic peptide receptor (GIPR) and luteinizing hormone receptor (LHCGR) are G-protein coupled receptors with a wide tissue expression pattern. The aberrant expression of these receptors has been described in cases of ACTH-independent macronodular adrenal hyperplasia (AIMAH) and in some adenomas, resulting in the i
Publicado em: 2007
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7. ESTUDO MORFOFUNCIONAL DAS CÉLULAS DE SERTOLI DE RATOS ALBINOS TRATADOS COM ETOPOSIDE NA FASE PRÉ-PÚBERE. / Morphological and functional evalution of Sertoli cells from albino treated with etoposide during preopubertal phase. / ESTUDO MORFOFUNCIONAL DAS CÉLULAS DE SERTOLI DE RATOS ALBINOS TRATADOS COM ETOPOSIDE NA FASE PRÉ-PÚBERE. / Morphological and functional evalution of Sertoli cells from albino treated with etoposide during preopubertal phase.
Spermatogenesis is a complex and controlled process in which Sertoli cells play a key role. In the testis, endocrine, paracrine and autocrine mechanisms that control spermatogenesis occurrence. The Sertoli cells synthesize substances which are essential for these mechanisms. Among them is transferrin. This protein is an important iron transporter that binds
Publicado em: 2006
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8. Isolation and characterization of differentially expressed genes in human benign insulinomas / Isolamento e caracterização de genes diferencialmente expressos em insulinomas benigos humanos
Os insulinomas são os mais comuns neoplasmas endócrinos pancreáticos, constituindo cerca de 17% de todos os tumores neuroendócrinos do trato digestivo. São tumores raros, que tem, como principal manifestação clínica, a hipoglicemia, a qual é ocasionada por secreção exagerada de insulina pelo tumor. Devido ao fato de serem tumores raros, o conhecim
Publicado em: 2005
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9. Lack of mutations of exon 2 of the MEN1 gene in endocrine and nonendocrine sporadic tumors
In addition to the mutations that underlie most cases of the multiple endocrine neoplasia type 1 (MEN1) syndrome, somatic mutations of the MEN1 gene have also been described in sporadic tumors like gastrinomas, insulinomas and bronchial carcinoid neoplasm. We examined exon 2 of this gene, where most of the mutations have been described, in 148 endocrine and
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-07
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10. "Syndrome myxoma": a subset of patients with cardiac myxoma associated with pigmented skin lesions and peripheral and endocrine neoplasms.
From January 1954 to December 1985 cardiac myxoma was diagnosed in 75 patients at the Mayo Clinic. The clinical presentation was typical in 70 cases and was referred to as "sporadic myxoma". Forty four other cases of cardiac myxomas (five from the Mayo Clinic) presented with a combination of distinctive clinical features and these cases are described as "syn
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11. Cushing's syndrome associated with recurrent endometrioid adenocarcinoma of the ovary.
Ectopic production of adrenocorticotrophic hormone (ACTH) by malignant neoplasms is a well recognised cause of Cushing's syndrome but is extremely rare in ovarian carcinoma. A patient who underwent surgery for ovarian carcinoma followed by a course of chemotherapy is reported. The tumour was a bilateral moderately differentiated endometrioid adenocarcinoma a
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12. Detection of apoptosis by the TUNEL technique in clinically localised prostatic cancer before and after combined endocrine therapy.
AIMS: Apoptosis in prostate cancer was evaluated after three months of combined endocrine therapy to investigate the association with tumour grade, tumour stage, and the immunohistochemical detection of p53 and bcl-2 in tumour cells before and after therapy. METHODS: Twenty six formalin fixed, paraffin wax embedded core biopsies and corresponding prostatecto