Entorhinal Cortex
Mostrando 1-12 de 64 artigos, teses e dissertações.
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1. Padrão da atividade locomotora e expressão de EAAC1 e GLT1 no córtex pré-frontal e entorrinal de ratos criados em isolamento a partir do desmame / Pattern of locomotor activity and expression of EAAC1 and GLT1 in prefrontal and entorhinal cortex of rats reared in isolation from weaning
Isolation rearing of rats from weaning has been used as an experimental model of psychiatric disorders like schizophrenia. It has been demonstrated that isolation induces morphological, behavioral (like hyperactivity in a novel environment) and neurochemical changes similar to those reported for humans with schizophrenia. Evidence suggest that glutamatergic
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/07/2012
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2. Neuropsychological and neurobiological markers of the preclinical stage of Alzheimer's disease
Dementia, especially Alzheimer's disease, has a high prevalence in the elderly population. Therefore, identifying individuals who are at a high risk for early diagnosis is crucial to allow both pharmacological and behavioral therapeutic interventions, which in some cases can delay the progression of dementia. This paper describes neuropsychological and neuro
Psychology & Neuroscience. Publicado em: 2011
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3. Involvement of the hippocampus, amygdala, entorhinal cortex in memory consolidation
A total of 182 young adult male Wistar rats were bilaterally implanted with cannulae into the CA1 region of the dorsal hippocampus and into the amygdaloid nucleus, the entorhinal cortex, and the posterior parietal cortex. After recovery, the animals were trained in a stepdown inhibitory avoidance task. At various times after training (0, 30, 60 or 90 min) th
Publicado em: 2010
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4. Differential role of entorhinal and hippocampal nerve growth factor in short- and long-term memory modulation
We studied the effects of infusion of nerve growth factor (NGF) into the hippocampus and entorhinal cortex of male Wistar rats (250-300 g, N = 11-13 per group) on inhibitory avoidance retention. In order to evaluate the modulation of entorhinal and hippocampal NGF in shortand long-term memory, animals were implanted with cannulae in the CA1 area of the dorsa
Publicado em: 2010
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5. Metabolic Approach to Evaluate Neuroprotection Promoted by A1 Adenosine Agonist in Pilocarpine-induced Epilepsy. / Abordagem Metabólica na Avaliação da Neuroproteção Promovida pelo Agonista Adenosinérgico A1 no Modelo de Epilepsia Induzida por Pilocarpina.
It is well known that the mismatch between local cerebral glucose utilization (LCGU) and local cerebral blood flow (LCBF) are frequently associated with seizure-induced neuronal damage in adult animal. This study was performed to verify if the neuroprotective effect of adenosinergic A1 receptor agonist R-Pia injected prior to pilocarpine could modulate LCGU
Publicado em: 2009
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6. Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders
Hippocampal output is increased in affective disorders and is mediated by increased glutamatergic input via N-methyl-D-aspartate (NMDA) receptor and moderated by antidepressant treatment. Activation of NMDA receptors by glutamate evokes the release of nitric oxide (NO) by the activation of neuronal nitric oxide synthase (nNOS). The human hippocampus contains
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-04
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7. Differential role of entorhinal and hippocampal nerve growth factor in short- and long-term memory modulation
We studied the effects of infusion of nerve growth factor (NGF) into the hippocampus and entorhinal cortex of male Wistar rats (250-300 g, N = 11-13 per group) on inhibitory avoidance retention. In order to evaluate the modulation of entorhinal and hippocampal NGF in short- and long-term memory, animals were implanted with cannulae in the CA1 area of the dor
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-01
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8. Entorhinal cortex involvement in human mesial temporal lobe epilepsy
Arquivos de Neuro-Psiquiatria. Publicado em: 2004-12
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9. Pharmacological differences between memory consolidation of habituation to an open field and inhibitory avoidance learning
Rats implanted bilaterally with cannulae in the CA1 region of the dorsal hippocampus or the entorhinal cortex were submitted to either a one-trial inhibitory avoidance task, or to 5 min of habituation to an open field. Immediately after training, they received intrahippocampal or intraentorhinal 0.5-µl infusions of saline, of a vehicle (2% dimethylsulfoxide
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-02
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10. Afferent connections of the amygdalopiriform transition area (APir) of the rat. / Conexões aferentes da área de transição amígdalo-piriforme (APir) no rato.
The amygdalo-piriform transition area (APir) lies at the junction of the piriform, periamygdaloid and entorhinal cortices. The afferent connections of this olfactory district were studied with retrograde tracing methods using the cholera toxin B subunit and Fluoro-Gold as tracers. Our retrograde experiments showed that the main input sources to APir derive f
Publicado em: 1999
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11. Postsynaptic Hebbian and non-Hebbian long-term potentiation of synaptic efficacy in the entorhinal cortex in slices and in the isolated adult guinea pig brain.
Long-term potentiation (LTP) was investigated in the mammalian entorhinal cortex by using two in vitro preparations, the isolated brain and the entorhinal cortex slice. Hebbian and non-Hebbian types of LTP appear to be present in layer II entorhinal cortex cells as demonstrated using two protocols: (i) tetanic stimulation of the piriform-entorhinal cortex af
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12. Increasing Acetylcholine Levels in the Hippocampus or Entorhinal Cortex Reverses the Impairing Effects of Septal GABA Receptor Activation on Spontaneous Alternation
Intra-septal infusions of the γ-aminobutyric acid (GABA) agonist muscimol impair learning and memory in a variety of tasks. This experiment determined whether hippocampal or entorhinal infusions of the acetylcholinesterase inhibitor physostigmine would reverse such impairing effects on spontaneous alternation performance, a measure of spatial working memory
Cold Spring Harbor Laboratory Press.