Equid Herpesvirus 1
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Molecular characterization of Brazilian equid herpesvirus type 1 strains based on neuropathogenicity markers
Partial nucleotide sequences of ORF72 (glycoprotein D, gD), ORF64 (infected cell protein 4, ICP4) and ORF30 (DNA polymerase) genes were compared with corresponding sequences of EHV-1 reference strains to characterize the molecular variability of Brazilian strains. Virus isolation assays were applied to 74 samples including visceral tissue, total blood, cereb
Braz. J. Microbiol.. Publicado em: 2015-06
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2. Atividade antiviral de extratos de plantas do Cerrado contra herpesvírus / Antiviral activity of Brazilian Cerrado plants extracts against Herpesvirus
Herpesviruses are responsible for important diseases in humans and animals. In animals, they are associated with economically important diseases worldwide. In humans, they represent serious threats to public health, and the severity of the illness increases in immunocompromised patients. In addition, there are mutant strains that are resistant to available d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/07/2011
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3. Atividade antiviral da quercetina sobre alguns vírus de importância veterinária / Antiviral activity of the quercetin against important virus of veterinary medicine
The search for new substances with potential antimicrobials is growing and is necessary due, mainly, to the development of resistance of infectious agents to the current drugs. Natural compounds, among them flavonoids, have been a particularly rich source of these antimicrobial agents. The objective of this work was to evaluate the antiviral potential of fla
Publicado em: 2007
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4. Characterization of Brazilian isolates of equine herpesvirus type A / Caracterização genomica de isolados brasileiros do herpesvirus equino do tipo 1
Equine Herpesvirus Type 1 (EHV-1) is a member of Alphaherpesvirinae subfamily implicated with abortions, respiratory and neurological disturbs in horses. The principal mode of viral transmission is through close contact virus-containing secretions of infected horses. Systemic pathogenesis in which this virus is implicated combines primary respiratory infecti
Publicado em: 2005
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5. Measurement of neutralizing antibody to equid herpesvirus 1 by single radial hemolysis.
Antibody to equid herpesvirus 1, which mediates single radial hemolysis, is that responsible for neutralization. Hemagglutination inhibition antibody is not necessarily involved in neutralization or hemolysis.
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6. Detection of latency-associated transcripts of equid herpesvirus 1 in equine leukocytes but not in trigeminal ganglia.
Results from Southern hybridization and PCR amplification experiments using a randomly synthesized reverse transcription-PCR product showed that peripheral blood leukocytes from horses showing no clinical signs of disease expressed a putative latency-associated transcript antisense to and overlapping the 3' end of the equid herpesvirus 1 (EHV-1) immediate-ea
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7. Relative activities of acyclovir and BW759 against Aujeszky's disease and equine rhinopneumonitis viruses.
Compound BW759 (9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine) was shown to be about 230 times more active than acyclovir (9-[2-hydroxyethoxymethyl]guanine) (ACV) against Equid herpesvirus type 1 infection in Syrian hamsters and was more effective against Aujeszky's disease in mice. The therapeutic superiority of BW759 over ACV was greater than expected
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8. Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxy-methylbut-1-yl)guanine (BRL 39123) in cell culture.
The activity of 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine (BRL 39123) against several herpesviruses was compared with that of acyclovir (ACV). In plaque reduction tests with clinical isolates of herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and varicella-zoster virus, mean 50% inhibitory concentrations (IC50S) (n = number teste