Etomidate
Mostrando 1-12 de 16 artigos, teses e dissertações.
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1. Comparison of the influence of low dose etomidate and propofol as priming dose on the incidence of etomidate induced myoclonus: a randomised, double-blind clinical trial
Abstract Background: Though hemodynamically stable, etomidate is known for its myoclonus side effect following induction. The main aim of this study is an effective attempt to decrease the incidence of myoclonus with a priming agent. Methods: A prospective, double-blind study was carried out on 50 adults posted for elective surgery. After premedication, pr
Brazilian Journal of Anesthesiology. Publicado em: 2022
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2. Efeito do pré-tratamento com gabapentina sobre a mioclonia após etomidato: um estudo randômico, duplo-cego e controlado por placebo
Resumo Objetivo: Avaliar os efeitos de três doses diferentes de gabapentina como pré-tratamento sobre a incidência e a gravidade dos movimentos mioclônicos associados à injeção de etomidato. Método: Cem pacientes, entre 18-60 anos, estado físico ASA I-II, programados para cirurgia eletiva sob anestesia geral, foram incluídos no estudo. Os pacient
Rev. Bras. Anestesiol.. Publicado em: 2016-08
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3. Rapid response of hypercortisolism to vandetanib treatment in a patient with advanced medullary thyroid cancer and ectopic Cushing syndrome
Medullary thyroid carcinoma (MTC) may rarely present with paraneoplastic syndromes. Among the most frequent ones are the appearance of diarrhea and ectopic Cushing syndrome (ECS). The ECS in the context of MTC is usually present in patients with distant metastatic disease. The use of drugs such as ketoconazole, metyrapone, somatostatin analogs and etomidate
Arch. Endocrinol. Metab.. Publicado em: 2015-08
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4. Effects of conventional vs high-dose rocuronium on the QTc interval during anesthesia induction and intubation in patients undergoing coronary artery surgery: a randomized, double-blind, parallel trial
Myocardial ischemia, as well as the induction agents used in anesthesia, may cause corrected QT interval (QTc) prolongation. The objective of this randomized, double-blind trial was to determine the effects of high- vs conventional-dose bolus rocuronium on QTc duration and the incidence of dysrhythmias following anesthesia induction and intubation. Fifty pat
Braz J Med Biol Res. Publicado em: 24/02/2015
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5. Prevention of etomidate-induced myoclonus during anesthetic induction by pretreatment with dexmedetomidine
Myoclonus induced by etomidate during induction of general anesthesia is undesirable. This study evaluated the effect of dexmedetomidine (DEX) pretreatment on the incidence and severity of etomidate-induced myoclonus. Ninety patients undergoing elective surgical procedures were randomly allocated to three groups (n=30 each) for intravenous administration of
Braz J Med Biol Res. Publicado em: 24/10/2014
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6. Evaluation of hemodynamic effects of xenon in dogs undergoing hemorrhagic shock
OBJECTIVES: The anesthetic gas xenon is reported to preserve hemodynamic stability during general anesthesia. However, the effects of the gas during shock are unclear. The objective of this study was to evaluate the effect of Xe on hemodynamic stability and tissue perfusion in a canine model of hemorrhagic shock. METHOD: Twenty-six dogs, mechanically ventila
Clinics. Publicado em: 2013
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7. Nanoemulsões como sistemas de liberação parenteral de fármacos
Lipid nanoemulsions have recently been proposed as parenteral delivery systems for poorly-soluble drugs. These systems consist of nanoscale oil/water dispersions stabilized by an appropriate surfactant system in which the drug is incorporated into the oil core and/or adsorbed at the interface. This article reviews technological aspects of such nanosystems, i
Quím. Nova. Publicado em: 2012
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8. Anestesia por infusão contínua de etomidato e etomidato associado ao remifentanil em gatas premedicadas com acepromazina / Continuous infusion anesthesia using etomidate and etomidate associated with remifentanil in cats premedicated with acepromazine
O etomidato é um derivado imidazólico, classificado como anestésico geral, não barbitúrico, com ação hipnótica de uso intravenoso. O remifentanil é um opióide μ-agonista seletivo, de ultracurta duração, que apresenta alta potência analgésica e farmacocinética singular, pois possui em sua cadeia química, um ramo lateral metiléster que pe
Publicado em: 2009
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9. Effects of propofol, etomidate, tiopental and epidural anesthesia in neonate and bitches elective caesarian section / Efeitos do propofol, etomidato, tiopental e anestesia epidural em neonatos e em cadelas submetidas a cesariana eletiva
A cesariana, geralmente um procedimento de emergência, deve contar com técnicas anestésicas seguras para mãe e fetos, que ao mesmo tempo, possibilite a realização da cirurgia em tempo hábil, liberando os filhotes em estado vigoroso. Todos os fármacos anestésicos utilizados em cesarianas atravessam rapidamente a placenta, podendo de alguma forma afet
Publicado em: 2003
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10. The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid
The γ-aminobutyric acid type A (GABAA) receptor is a transmitter-gated ion channel mediating the majority of fast inhibitory synaptic transmission within the brain. The receptor is a pentameric assembly of subunits drawn from multiple classes (α1–6, β1–3, γ1–3, δ1, and ɛ1). Positive allosteric modulation of GABAA receptor activity by general anes
The National Academy of Sciences of the USA.
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11. Neurosteroids Allosterically Modulate Binding of the Anesthetic Etomidate to γ-Aminobutyric Acid Type A Receptors*S⃞
Photoaffinity labeling of γ-aminobutyric acid type A (GABAA)-receptors (GABAAR) with an etomidate analog and mutational analyses of direct activation of GABAAR by neurosteroids have each led to the proposal that these structurally distinct general anesthetics bind to sites in GABAARs in the transmembrane domain at the interface between the β and α su
American Society for Biochemistry and Molecular Biology.
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12. Calcium channel currents in bovine adrenal chromaffin cells and their modulation by anaesthetic agents.
1. The calcium channel currents of bovine adrenal chromaffin cells were characterized using a variety of voltage pulse protocols and selective channel blockers before examination of their modulation by anaesthetic agents. 2. All the anaesthetics studied (halothane, methoxyflurane, etomidate and methohexitone) inhibited the calcium channel currents in a conce