Experimental Blocking
Mostrando 1-12 de 151 artigos, teses e dissertações.
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1. Co-transfection of hepatocyte growth factor and truncated TGF-β type II receptor inhibit scar formation
Wound scarring remains a major challenge for plastic surgeons. Transforming growth factor (TGF)-β plays a key role in the process of scar formation. Previous studies have demonstrated that truncated TGF-β type II receptor (t-TGF-βRII) is unable to continue signal transduction but is still capable of binding to TGF-β, thereby blocking the TGF-β signaling
Braz J Med Biol Res. Publicado em: 2020-01
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2. Wheel-flat detection on trams using envelope analysis with Hilbert transform
Abstract The wheel-flat defect is one of the many issues decreasing the level of and comfort in light rail vehicles. The two main causes of wheel-flats are temporary or complete wheel blocking. The negative effect is the increase of the dynamic phenomenons in the wheel-rail interaction, which are impulsive in their nature. It could prove to be dangerous for
Lat. Am. j. solids struct.. Publicado em: 18/02/2019
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3. Kn-Ba: a novel serine protease isolated from Bitis arietans snake venom with fibrinogenolytic and kinin-releasing activities
Abstract Background: Bitis arietans is a venomous snake found in sub-Saharan Africa and in parts of Morocco and Saudi Arabia. The envenomation is characterized by local and systemic reactions including pain, blistering, edema and tissue damage, besides hemostatic and cardiovascular disturbances, which can cause death or permanent disabilities in its victims
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 24/01/2019
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4. Platelet activating factor receptor antagonists improve the efficacy of experimental chemo- and radiotherapy
Platelet activating factor is a lipid mediator of inflammation, and in recent decades, it has emerged as an important factor in tumor outcomes. Platelet activating factor acts by specific binding to its receptor, which is present in both tumor cells and cells that infiltrate tumors. Pro-tumorigenic effects of platelet activating factor receptor in tumors inc
Clinics. Publicado em: 11/10/2018
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5. Repeatability of the “flash-replenishment” method in contrast-enhanced ultrasound for the quantitative assessment of hepatic microvascular perfusion
This study aimed to evaluate the feasibility and repeatability of the flash-replenishment method in contrast-enhanced ultrasound (CEUS) perfusion imaging and assess quantitatively microvascular perfusion in the liver. Twenty healthy New Zealand rabbits were submitted to CEUS perfusion imaging with continuous intravenous infusion. Using flash-replenishment ki
Braz J Med Biol Res. Publicado em: 26/02/2018
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6. Clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgery
Retrograde autologous priming (RAP) has been routinely applied in cardiac pediatric cardiopulmonary bypass (CPB). However, this technique is performed in pediatric patients weighing more than 20 kg, and research about its application in pediatric patients weighing less than 20 kg is still scarce. This study explored the clinical application of RAP in CPB in
Braz J Med Biol Res. Publicado em: 26/04/2016
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7. Effects of blocking αvβ3 integrin by a recombinant RGD disintegrin on remodeling of wound healing after induction of incisional hernia in rats
PURPOSE: To investigate the changes induced by DisBa-01 on repair of wound healing after induced incisional hernia (IH) in rats. METHODS: Thirty two male albino rats were submitted to IH and divided into four experimental groups: G1, placebo control; G2, DisBa-01-treated; G3, anti-αvβ3 antibodies-treated and G4, anti-α2 antibodies-treated. Histological,
Acta Cir. Bras.. Publicado em: 2015-02
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8. Effects of Blocking αvβ3 integrin by a recombinant RGD disintegrin on remodeling of wound healing after induction of incisional hernia in rats
PURPOSE: Incisional hernia (IH) is characterized by defective wound healing process. Disba-01, a αvb3 integrin blocker has shown to control the rate of wound repair and therefore it could be a target for new wound healing therapies.The objective of the study was to determine the changes induced by Disba-01 on repair of wound healing after induced IH in rat
Acta Cir. Bras.. Publicado em: 2014
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9. Digestible threonine to lysine ratio in diets for laying hens aged 24-40 weeks
Two-hundred sixteen white laying hens were used to assess the ideal ratio of digestible threonine:lysine in diets for laying hens at 24 to 40 weeks of age. Birds were assigned to a randomized block design, with six treatments, six replicates per treatment and six birds per experimental unit. The cage was used as the blocking criterion. Experimental diets con
R. Bras. Zootec.. Publicado em: 2013-12
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10. A surface-renewal model of cross-flow microfiltration
A mathematical model using classical cake-filtration theory and the surface-renewal concept is formulated for describing cross-flow microfiltration under dynamic and steady-state conditions. The model can predict the permeate flux and cake buildup in the filter. The three basic parameters of the model are the membrane resistance, specific cake resistance and
Braz. J. Chem. Eng.. Publicado em: 2013-03
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11. Investigação da reação de Morita-Baylis-Hillman em reator de micro-ondas usando aldeídos aromáticos e isatina como eletrófilos: avaliação da atividade citotóxica em linhagem de células de leucemia promielocítica humanas (HL-60). / Investigation of Morita-Baylis-Hillman Reaction on Microwave Reactor using Aromatic Aldehydes and Isatin as Eletrophiles: Evaluation of Cytotoxic Activity in cell line human promyelocytic leukemia (HL-60).
In this work, we describe the investigation of the Morita-Baylis-Hillman reaction in microwave reactor, under closed vessel conditions to prepare 40 adducts, six novel, using 30 aromatic aldehydes and isatin as electrophiles and acrylonitrile (62a) , methyl acrylate (2), hydroxyethyl acrylate (62b), 2,2-dimethyl-1 ,3-dioxalyl acrylate (62c) and 2,3-dihydroxy
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/11/2012
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12. Pore blocking mechanism for the recovery of milk solids from dairy wastewater by ultrafiltration
This paper evaluates the pore blocking mechanism of two ultrafiltration membranes with different geometries (tubular and spiral wound) when dairy wash water is filtered. The work evaluated the effect of transmembrane pressure and the cross-flow velocity with a 3² experimental design using classical Hermia's models and the resistance-in-series model. The res
Brazilian Journal of Chemical Engineering. Publicado em: 2012-06