Experimental Tuberculosis
Mostrando 1-12 de 153 artigos, teses e dissertações.
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1. NOVAS TECNOLOGIAS PARA O TRATAMENTO DA TUBERCULOSE: O QUE AS PATENTES NOS DIZEM
Tuberculosis still is the world’s leading cause of death from a single infectious agent and has affected approximately 10 million people in 2018. The development of new technologies for treating tuberculosis is among the priority goals for the global fight against the disease. The present work makes a technological prospecting from patent documents, aiming
Quím. Nova. Publicado em: 20/07/2020
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2. Roles of monocyte chemotactic protein 1 and nuclear factor-κB in immune response to spinal tuberculosis in a New Zealand white rabbit model
This study aimed to explore the roles of monocyte chemotactic protein 1 (MCP-1) and nuclear factor kappa B (NF-κB) in immune response to spinal tuberculosis in a New Zealand white rabbit model. Forty-eight New Zealand white rabbits were collected and divided into four groups: experimental group (n=30, spinal tuberculosis model was established), the sham gro
Braz J Med Biol Res. Publicado em: 20/02/2017
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3. Padronização de modelo experimental adequado a estudos do efeito do exercício na artrite
OBJETIVO: Padronizar um modelo experimental de monoartrite crônica induzida por adjuvante completo de Freund apropriado à análise do efeito da deambulação na nocicepção e no edema articular. MÉTODOS: Foram avaliados os seguintes fatores para a indução da monoartrite: via e local de administração, número e intervalo das inoculações, espécie de
Einstein (São Paulo). Publicado em: 2013-03
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4. Antigen-presenting cells transfected with Hsp65 messenger RNA fail to treat experimental tuberculosis
In the last several years, the use of dendritic cells has been studied as a therapeutic strategy against tumors. Dendritic cells can be pulsed with peptides or full-length protein, or they can be transfected with DNA or RNA. However, comparative studies suggest that transfecting dendritic cells with messenger RNA (mRNA) is superior to other antigen-loading t
Braz J Med Biol Res. Publicado em: 2012-12
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5. Consulta de enfermagem baseada na teoria de orem para pacientes com coinfecÃÃo hiv/tuberculose: efetividade na adesÃo e qualidade de vida / Nursing consultation based on Oremâs Theory for patients co-infected with HIV/Tuberculosis: efficacy for adherence and quality of life
A gravidade clÃnica e a demanda social de pacientes coinfectados HIV/tuberculose exigem mudanÃas no saber e no fazer da enfermagem diante dos cuidados em saÃde, especialmente de promoÃÃo a saÃde. Neste contexto, este estudo objetivou: elaborar e validar o conteÃdo de um instrumento de consulta de enfermagem direcionado para pacientes com coinfecÃÃo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/02/2011
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6. Further studies on membrane stabilizing, anti-inflammatory and FCA induced arthritic activity of various fractions of bark of Machilus macrantha in rats
Machilus macrantha Nees, Lauraceae, bark is traditionally used in the treatment of asthma, tuberculosis and rheumatoid arthritis. In order to validate, mechanism based anti-inflammatory activity of fractions M. macrantha bark are investigated for first time. Test materials viz. petroleum ether (PE), alkaloidal fraction (CH), acetone extracts (TAN) and mucila
Revista Brasileira de Farmacognosia. Publicado em: 26/08/2011
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7. Synthesis and enzymatic evaluation of the guanosine analogue 2-amino-6-mercapto-7-methylpurine ribonucleoside (MESG). Insights into the phosphorolysis reaction mechanism based on the blueprint transition state: sn1 or sn2
A modificação experimental para a síntese do MESG (2-amino-6-mercapto-7-metilpurina ribonucleosídeo) 1 foi realizada com sucesso e sua caracterização total apresentada. ESI(+)-MSMS em alta resolução foram realizados indicando que a clivagem nucleosídica como principal e um possível mecanismo SN1. Cálculos ab initio baseados em estados de transiç�
Publicado em: 2011
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8. Impacto da inflamação aguda sobre a plasticidade sinaptica de motoneuronios espinhais apos avulsão das raizes nervosas / Impact of acute inflammation on spinal motoneuron synaptic plasticity following ventral root avulsion
A avulsão das raízes nervosas ventrais (ARV) promove a axotomia dos motoneurônios na interface entre o sistema nervoso central e periférico. Sabe-se que apesar da intensa reação inflamatória, esta lesão, quando realizada durante o curso da encefalomielite autoimune experimental (EAE), resgata um significativo número de motoneurônios. A interpretaç
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/03/2010
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9. Fungos, instituições, máquinas e pessoas em negociação : o percurso do fármaco P-Mapa / Fungi, institutions, machines and people in negotiation : the course of the P-Mapa drug
This work describes the diversity of human and non-humans actors - fungi, physicians, veterinarians, mice, chickens, dogs, patients, academic researchers, lawyers, non-governmental organizations, businessmen, funding agency heads, ad hoc referees, ministers, ministry officers, journalists, viruses, bacteria, and computers - who have met and separated, connec
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/03/2010
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10. Leukotrienes are not essential for the efficacy of a heterologous vaccine against Mycobacterium tuberculosis infection
Leukotrienes are reported to be potent proinflammatory mediators that play a role in the development of several inflammatory diseases such as asthma, rheumatoid arthritis and periodontal disease. Leukotrienes have also been associated with protection against infectious diseases. However, the role of leukotrienes in Mycobacterium tuberculosis infection is not
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-07
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11. A enzima 2-trans-enoil-ACP (COA) redutase de Mycobacterium tuberculosis : inibição por um novo composto e estudos espectroscópicos do seu mecanismo de resistência à hidrazida do ácido isonicotínico
Tuberculosis (TB) is a neglected disease, which continue to be major cause of morbidity and mortality worldwide, killing together around 5 million people each year. Mycolic acids, the hallmark of mycobacteria, are high-molecular-weight α-alkyl, β-hydroxy fatty acids. Biochemical and genetic experimental data have shown that the product of the M. tuberculos
Publicado em: 2010
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12. Assessment of T-SPOT-TB test for the diagnosis of latent tuberculosis infection in patients with psoriasis / Avaliação do teste T-SPOT.TB no diagnóstico de infecção tuberculosa latente em pacientes com psoríase
Introduction: The therapy for psoriasis was modified by the introduction of immunebiological products that allow better disease control and better quality of life for patients, but promotes increased risk forf latent tuberculosis, requiring diagnosis shortly before its establishment. Purpose: To assess the performance of T-SPOT.TB test for the diagnosis of l
Publicado em: 2010