Extracellular Matrix Of Lymph Nodes
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Alterações da matriz extracelular do fígado, baço e linfonodos cervicais de cães naturalmente infectados com Leishmania (Leishmania) chagasi
The aim of this work was study the extracellular matrix alterations in liver, spleen and cervical lymph nodes in dogs naturally infected with Leishmania (Leishmania) chagasi correlating with clinical aspects, histological, parasitological and immunological. This study was carried out with 30 dogs, divided at three groups: ten not infected animals (group cont
Publicado em: 2008
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2. Análise histomorfométrica da matriz extracelular do linfonodo poplíteo de cães naturalmente infectados por Leishmania (L.) chagasi / Histomorphometric analysis of the extracellular matrix of popliteal lymph nodes from dogs naturally infected by Leishmania (L.) chagasi
As espécies do gênero Leishmania são protozoários que alternativamente parasitam seus vetores flebotomíneos e os macrófagos dos mamíferos. Os parasitos depositados na pele do mamífero pelo flebótomo infectado ultrapassam a matriz extracelular (MEC) para em seguida migrarem para outros órgãos. A MEC é um complexo estrutural que envolve e dá supor
Publicado em: 2008
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3. Análise de células CD4+CD25+FoxP3+ no timo de camundongos infectados pelo Trypanosoma cruzi. / Analysis of cells CD4 CD25 FoxP3 in the thymus of mice infected for the Trypanosoma cruzi.
Natural regulatory T cells arise in the thymus during the normal process of differentiation and participate in the control of auto and alloimmune responses. Specifically in parasite infections, these cells may have antagonist roles, in favor of the microorganism or the host. Previous studies from our Laboratory revealed that acute Trypanosoma cruzi (T. cruzi
Publicado em: 2008
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4. Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin.
Human melanoma is a highly metastatic cancer and the regional lymph nodes are generally the first site of metastasis. Adhesion to cryostat sections of human lymph nodes was therefore studied using two human melanoma models established from lymph node metastases, namely, MeWo cell lines of diverse metastatic potentials and a highly metastatic cell line of rec
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5. Binding of Candida albicans yeast cells to mouse popliteal lymph node tissue is mediated by macrophages.
We previously reported that Candida albicans yeast cells adhere to the macrophage-rich medullary and subcapsular sinus areas of mouse lymph node tissue. To determine whether the yeast cell-lymph node interaction is mediated by macrophages, the effect of specific elimination of macrophages on yeast cell binding was studied, and yeast cell adherence was correl
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6. Galectin-1 Co-clusters CD43/CD45 on Dendritic Cells and Induces Cell Activation and Migration through Syk and Protein Kinase C Signaling*
Galectin-1 is a galactoside-binding lectin expressed in multiple tissues that has pleiotropic immunomodulatory functions. We previously showed that galectin-1 activates human monocyte-derived dendritic cells (MDDCs) and triggers a specific genetic program that up-regulates DC migration through the extracellular matrix, an integral property of mucosal DCs. He
American Society for Biochemistry and Molecular Biology.
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7. Overexpression of plasminogen activator inhibitor 2 in human melanoma cells inhibits spontaneous metastasis in scid/scid mice.
A metastatic human melanoma cell line that produces urokinase-type plasminogen activator was stably transfected with cDNA encoding human plasminogen activator inhibitor 2 (PAI-2). Transfected clones expressed PAI-2 at levels two to nine times higher than both the parental cell line and mock transfectants, as detected by ELISA of cell lysates and conditioned
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8. Core3 O-Glycan Synthase Suppresses Tumor Formation and Metastasis of Prostate Carcinoma PC3 and LNCaP Cells through Down-regulation of α2β1 Integrin Complex*
Although there are numerous reports of carbohydrates enriched in cancer cells, very few studies have addressed the functions of carbohydrates present in normal cells that decrease in cancer cells. It has been reported that core3 O-glycans are synthesized in normal gastrointestinal cells but are down-regulated in cancer cells. To determine the roles of core3
American Society for Biochemistry and Molecular Biology.
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9. Regulation of immune activity by mild (fever-range) whole body hyperthermia: effects on epidermal Langerhans cells
Inflammation of the skin and systemic fever, both of which occur with injury or infection, include a hyperthermic component that many believe constitutes a physiological stress. Such increases in local or systemic body temperature may also have a regulatory effect on immune function. Langerhans cells (LCs), the dendritic cells of the skin, continuously monit
Cell Stress Society International.