Fatty Liver Therapy
Mostrando 1-12 de 17 artigos, teses e dissertações.
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1. N-ACETYLCYSTEINE AND/OR URSODEOXYCHOLIC ACID ASSOCIATED WITH METFORMIN IN NON-ALCOHOLIC STEATOHEPATITIS: AN OPEN-LABEL MULTICENTER RANDOMIZED CONTROLLED TRIAL
RESUMO CONTEXTO: Atualmente, o tratamento farmacológico da doença hepática gordurosa não alcoólica (DHGNA) ainda é limitado e baseia-se no tratamento de condições associadas às comorbidades. O estresse oxidativo e a resistência à insulina são os mecanismos que parecem estar mais envolvidos em sua patogênese. OBJETIVO: Avaliar a eficácia da
Arq. Gastroenterol.. Publicado em: 26/08/2019
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2. Acute Kidney Injury after Cardiac Surgery: Risk Factors and Novel Biomarkers
Abstract Acute kidney injury (AKI) is a common and severe complication after cardiac surgery. Currently, a series of novel biomarkers have favored the assessment of AKI after cardiac surgery in addition to the conventional indicators. The biomartkers, such as urinary liver fatty acid binding protein (L-FABP), urinary neutrophil gelatinase-associated lipocali
Braz. J. Cardiovasc. Surg.. Publicado em: 22/07/2019
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3. Exenatide ameliorates hepatic steatosis and attenuates fat mass and FTO gene expression through PI3K signaling pathway in nonalcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is a common disease associated with metabolic syndrome and can lead to life-threatening complications like hepatic carcinoma and cirrhosis. Exenatide, a glucagon-like peptide-1 (GLP-1) receptor agonist antidiabetic drug, has the capacity to overcome insulin resistance and attenuate hepatic steatosis but the specific
Braz J Med Biol Res. Publicado em: 14/06/2018
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4. Alopurinol na prevenção da esteato-hepatite não alcoólica e hiperglicemia induzida por dieta rica em frutose em ratos wistar
Nonalcoholic fatty liver disease (NAFLD) in the last two decades has been recognized as the most common chronic liver disease in Western countries, paralleling the epidemic of obesity and consumption of high-fructose diet. Researchers suggest that NAFLD may be the hepatic manifestation of metabolic syndrome. Although NAFLD and hyperuricemia are strongly rela
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/03/2012
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5. A influência da flora intestinal e da esplenectomia na resistência à insulina induzida por obesidade / Influence of gut microbiota and splenectomy over the obesity-induced insulin resistance
A high-fat diet intake induces obesity and chronic subclinical inflammation, which play important roles in insulin resistance. Increased circulating levels of proinflammatory cytokines, free fatty acids and lipopolysaccharides activate innate immune system, which triggers inflammation and cytokine expression, leading to insulin resistance. Thus, we investiga
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/03/2012
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6. Tratamento da doença hepática gordurosa não alcoólica exclusivamente com dieta, efeitos da intervenção nutricional sobre os valores das enzimas hepáticas, grau de esteatose e na resistência à insulina. / Diet therapy as exclusive treatment on nonalcoholic fatty liver disease. The effect of the nutrition intervension on liver enzymas, the degree of steatosis and insulin resistance
Objetivo: Avaliar o efeito da intervenção nutricional como tratamento exclusivo na resistência à insulina, parâmetros bioquímicos de síndrome metabólica e grau de esteatose hepática em portadores de doença hepática gordurosa não alcoólica (DHGNA). Métodos: 31 portadores de DHGNA, diagnosticados por tomografia computadorizada e/ou biópsia hepá
Publicado em: 2009
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7. Esteato-hepatite não alcoólica (ENA) em camundongos obesos (ob/ob): avaliação do efeito citoprotetor do Yo Jyo Hen Shi Ko (YHK) / YO JYO HEN SHI KO, a novel Chinese herbal, prevents nonalcoholic steatohepatitis in ob/ob mice fed a high fat or methionine/choline deficient diet
Background: Oxidative stress plays a role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Yo Jyo Hen Shi Ko (YHK) is a complex compound purported to reduce reactive oxygen species (ROS) by blocking the propagation of radical-induced reactions. Aim: The aim of this study was to evaluate the role of the effect of YHK in experimental NASH. Methods:
Publicado em: 2007
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8. Avaliação toxicológica subcrônica de dieta cetogênica à base de trienantina em ratos jovens. / Subchronic toxicologicalevaluation of a ketogenic diet based upon trienantin in rats.
The classic ketogenic diet, rich in long chain triacylglycerols (LCT), is characterised by a high concentration of lipids and a low concentation of carbohydrates and proteins, promoting ketonemia and ketonuria, a property used in the treatment of disorders that affect cerebral metabolism and function, for example epilepsy resistant to medication. Medium chai
Publicado em: 2007
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9. Efeitos da cirurgia de Fobi-Capella na doença hepática gordurosa não alcoólica (DHGNA): estudo prospectivo de dois anos / Effects of bariatric surgery (Fobi-Capella) in nonalcoholic fatty liver disease (NAFLD): prospective study of 2 years
Background: The incidence of obesity is increasing in western countries at an alarming rate. The National Center for Health Statistics of United Stated estimated in adult population 61% the prevalence of overweight or obesity, and 30% has obesity, and 5 to 6% were classified in severe obesity. In Brazil, the Ministry of Health reported 32.9% the prevalence o
Publicado em: 2006
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10. Hipertrigliceridemia aumenta a respiração de repouso mitocondrial e susceptibilidade a transição de permeabilidade
High plasma leveI of triglycerides is a common feature in atherosclerosis, obesity, diabetes, alcoholism, stress and infection. Since mitochondria have been implicated in cell death under a variety of metabolic disorders, we examined liver mitochondrial functions in hypertriglyceridemic transgenic mice. Hypertriglyceridemia increased resting respiration and
Publicado em: 2003
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11. Liver function in septic shock.
Serum liver function tests were estimated in 57 patients admitted to an Intensive Therapy Unit (ITU) with a diagnosis of septic shock. Following an initial biochemical disturbance, persisting hyperbilirubinaemia was associated with a poor prognosis. Post-mortem liver histology in 22 patients showed varying degrees of non-specific reactive change, venous cong
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12. Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets
Overaccumulation of lipids in nonadipose tissues of obese rodents may lead to lipotoxic complications such as diabetes. To assess the pathogenic role of the lipogenic transcription factor, sterol regulatory element binding protein 1 (SREBP-1), we measured its mRNA in liver and islets of obese, leptin-unresponsive fa/fa Zucker diabetic fatty rats. Hepatic SRE
The National Academy of Sciences.