Fibrogenesis
Mostrando 1-12 de 87 artigos, teses e dissertações.
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1. Candesartan, rather than losartan, improves motor dysfunction in thioacetamide-induced chronic liver failure in rats
Minimal hepatic encephalopathy is more common than the acute syndrome. Losartan, the first angiotensin-II receptor blocker (ARB), and candesartan, another widely-used ARB, have protected against developing fibrogenesis, but there is no clear data about their curative antifibrotic effects. The current study was designed to examine their effects in an already-
Braz J Med Biol Res. Publicado em: 21/09/2017
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2. Combination therapy with butyrate and docosahexaenoic acid for keloid fibrogenesis: an in vitro study
Abstract: Background: A single, effective therapeutic regimen for keloids has not been established yet, and the development of novel therapeutic approaches is expected. Butyrate, a short-chain fatty acid, and docosahexaenoic acid (DHA), a ω-3 polyunsaturated fatty acid, play multiple anti-inflammatory and anticancer roles via their respective mechanisms of
An. Bras. Dermatol.. Publicado em: 2017-03
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3. Platelet-derived growth factor A mRNA in platelets is associated with the degree of hepatic fibrosis in chronic hepatitis C
Abstract: INTRODUCTION: Transforming growth factor beta 1 (TGFB1) and platelet-derived growth factor (PDGF) are the main cytokines related to hepatic fibrogenesis. METHODS: RNA isolated from the platelets and hepatic tissue of 43 HCV carriers was used for quantitative polymerase chain reaction to determine TGFB1, PDGFA, and PDGFB RNA expression. RESULTS
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-02
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4. Fibrogenesis and epithelial coating of skin wounds in rats treated with angico extract (Anadenanthera colubrina var. cebil)
PURPOSE: To evaluate the effects of angico bark extract (Anadenanthera colubrina var. cebil) in the healing process of the skin of rats.METHODS: Twenty adult male rats were divided into four groups of five animals each, according to the respective postoperative days, as follow: G4, G7, G14 and G21. Each group received two incisions on skin and subcutaneous t
Acta Cir. Bras.. Publicado em: 2015-05
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5. Biocompatibility of the bacterial cellulose hydrogel in subcutaneous tissue of rabbits
PURPOSE: To evaluate the biocompatibility and local sensibility reaction to bacterial cellulose hydrogel (0.8%) implanted in subcutaneous tissue of rabbits.METHODS:Fifteen New Zeland rabbits were randomly allocated into three groups: T1, 7 days, T2, 21 days, and T3, 84 days. The new material was implanted in the subcutaneous tissue of the ear; on the scalp o
Acta Cir. Bras.. Publicado em: 2015-04
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6. Effect of sugarcane biopolymer in vocal fold of rabbits. Comparative study with calcium hydroxyapatite
PURPOSE:To compare the inflammatory reaction caused by the injection of a sugarcane biopolymer (SCB) into the vocal fold of rabbits with that caused by calcium hydroxyapatite (CaH).METHODS: CaH (Radiesse(r)) and SCB gel were injected respectively into the right and left vocal cords of thirty rabbits. The rabbits were distributed into two equal groups and sac
Acta Cir. Bras.. Publicado em: 2015-03
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7. Dynamic expression of desmin, α-SMA and TGF-β1 during hepatic fibrogenesis induced by selective bile duct ligation in young rats
We previously described a selective bile duct ligation model to elucidate the process of hepatic fibrogenesis in children with biliary atresia or intrahepatic biliary stenosis. Using this model, we identified changes in the expression of alpha smooth muscle actin (α-SMA) both in the obstructed parenchyma and in the hepatic parenchyma adjacent to the obstruc
Braz J Med Biol Res. Publicado em: 15/08/2014
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8. Efeito do Ácido Gálico sobre a fibrogênese hepática murina / Effect of Gallic Acid in murine hepatic fibrogenesis
The fibrogenic processes activate by mechanisms such as oxidative stress can lead to a picture of liver cirrhosis, which represents a major cause of death in West. However, in some studies, phenolic substances, such as Gallic Acid (GA) shown to inhibit and even regress theses processes. The aim of this study was to investigate the effects of the phenolic com
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/04/2012
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9. Effects of the administration of pentoxifylline and prednisolone on the evolution of portal fibrogenesis secondary to biliary obstruction in growing animals: immunohistochemical analysis of the expression of TGF-β and VEGF
OBJECTIVE: During the neonatal and infancy periods, some chronic liver diseases may lead to progressive hepatic fibrosis, which is a condition that can ultimately result in the loss of organ function and severe portal hypertension necessitating hepatic transplantation. In a previous report, pharmacological interventions were demonstrated to modulate hepatic
Clinics. Publicado em: 2012-12
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10. Fibrogenesis and carcinoid tumor - a case report
Tumores carcinoides são pouco frequentes, podem surgir em todo o trato gastrointestinal e respiratório, podem ser únicos ou múltiplos. O prognóstico depende do tamanho e da localização do tumor. Podem ocorrer sintomas relacionados à síndrome carcinoide, decorrente da produção de substâncias ativas, em especial serotonina. Um aspecto comumente ign
Journal of Coloproctology (Rio de Janeiro). Publicado em: 2012-06
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11. Contribuição para o estudo da fibrogenesis hepática em ratos infectados com Capillaria hepatica
INTRODUÇÃO: A fibrose septal do fígado se desenvolve regularmente em ratos infectados pelo nematódeo Capillaria hepatica. O tratamento curativo da infecção, feito antes do 15º dia da infecção, mas não mais tarde, impediu o aparecimento da fibrose septal. O presente trabalho procura verificar qual o estado do parasitismo aos 15 dias da infecção, c
Revista da Sociedade Brasileira de Medicina Tropical. Publicado em: 2010-10
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12. Angiogenesis and schistosomiasis
Angiogenesis has been recognised as a precursor of fibrosis in several pathologic conditions. Its participation has been demonstrated in schistosomiasis, both during periovular granuloma formation and in the genesis of schistosomal periportal fibrosis. Paradoxically, proliferation of new blood vessels, accompanied by production of vascular-endothelial growth
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-07