Fisetin
Mostrando 1-12 de 13 artigos, teses e dissertações.
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1. Caracterização eletroquímica de uma monocamada auto-organizada mista composta por ácido 3-mercaptopropiônico e ácido 11-mercaptoundecanóico / Electrochemical characterization of a mixed 3-mercaptopropionic and 11-mercaptoundecanoic acids self-assembled monolayer
Monocamadas auto-organizadas formadas pela quimissorção de alcanotióis sobre ouro apresentam estruturas bem definidas, organizadas e reprodutíveis. As propriedades de SAMs, aliadas à facilidade de síntese, têm atraído o interesse da comunidade cientifica o que ocasionou um grande avanço na área de nanotecnologia, especialmente em engenharia de supe
Publicado em: 2011
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2. ESTUDO FOTOQUÍMICO DA AÇÃO ANTI-RADICALAR DE COMPOSTOS POLIFENÓLICOS EMPREGANDO ESPECTROFOTOMETRIA E HPLC-UV
The interest in antioxidants has increased considerably in recent years as molecules that reduce lipid peroxidation may minimize or inhibit the oxidative damage caused to DNA, proteins and carbohydrates. Flavonoids, a group of secondary metabolites widely distributed in the plant kingdom, have properties of anti-inflammatory, antibacterial, antiviral, anti-a
Publicado em: 2010
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3. Desenvolvimento e aplicação de um novo ensaio para a determinação eletroquímica da capacidade antioxidante de compostos modelo e de matrizes complexas / Development and application of a new assay for the electrochemical determination of the antioxidant capacity of model compounds and of complex matrices
This work describes the development and practical applications of a novel and simple electrochemical methodology for the determination of the antioxidant capacity of specific model molecules and/or some complex food samples currently consumed in Brazil. Other systems having either theoretical or technological interest were also investigated. The method is ba
Publicado em: 2009
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4. Natural compounds as modulators of transduction pathways in tumor cells / Copostos naturais como moduladores de vias de transdução de sinal em celulas tumorais
The search for compounds that specifically act on tumors, with low side effects, is a great aim in the studies related to cancer treatment. Many natural compounds isolated from plants have presented promising results as modulating agents of the signal transduction pathways in several types of tumors. Flavonoids, polyphenolic compounds largely distributed in
Publicado em: 2008
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5. Mecanismo da ação antineoplasica de substancias bioativas e alvos moleculares estrategicos para a indução de morte de celulas tumorais / Antineoplastic action mechanism of bioactive compounds and strategical molecular targets for inducting tumoral cells death
Natural products have been providing numerous clinically used medicines and remain as essential components in the search for new drugs against various pharmacological targets including cancer, HIV/AIDS, Alzheimer?s, malaria, and pain. Drug discovery from natural products, especially from medicinal plants, has played an important role in the chemoprevention a
Publicado em: 2007
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6. Study of the Complexation of Fisetin with Cyclodextrins / Estudo da complexação da fisetina com ciclodextrinas
Neste trabalho de Mestrado, foram feitos estudos do comportamento fotofísico da fisetina em diversos solventes através de medidas de absorção de luz UV-Visível, fluorescência estática e resolvida no tempo e da interação entre fisetina (3,3,4,7-tetrahidroxiflavona) e 7-hidroxiflavona com ciclodextrinas ( beta e gama) (CDs) através de experimentos de
Publicado em: 2007
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7. Constituintes químicos da casca do caule de Amburana cearensis A.C. Smith
The phytochemical analysis of the ethanol extract trunk bark of Amburana cearensis allowed the isolation and identification of twelve constituents: coumarin, sucrose, two phenol acids (vanillic acid and protocatechuic acid), five flavonoids (afrormosin, isokaempferide, kaempferol, quercetin and 4'-methoxy-fisetin), a phenol glucoside (amburoside A) and a mix
Química Nova. Publicado em: 2006-12
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8. Neuroprotection by flavonoids
The high morbidity, high socioeconomic costs and lack of specific treatments are key factors that define the relevance of brain pathology for human health and the importance of research on neuronal protective agents. Epidemiological studies have shown beneficial effects of flavonoids on arteriosclerosis-related pathology in general and neurodegeneration in p
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-12
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9. Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint
Fisetin is a natural flavonol present in edible vegetables, fruits and wine at 2–160 μg/g concentrations and an ingredient in nutritional supplements with much higher concentrations. The compound has been reported to exert anticarcinogenic effects as well as antioxidant and anti-inflammatory activity via its ability to act as an inhibitor of cell prolifer
Oxford University Press.
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10. The hydroxyflavone, fisetin, suppresses mast cell activation induced by interaction with activated T cell membranes
Blackwell Publishing Ltd.
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11. Alfalfa Root Exudates and Compounds which Promote or Inhibit Induction of Rhizobium meliloti Nodulation Genes 1
Using a plate induction assay, we demonstrate that alfalfa exudes inducer of Rhizobium meliloti nodulation genes. The inducer is exuded from the infectible zone of the root, accumulates to at least 1 micromolar, and is not affected by 10 millimolar nitrate. No zones of inhibition are observed. A nodulation minus mutant line of alfalfa, MN-1008, exudes normal
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12. Interplay between excited-state intramolecular proton transfer and charge transfer in flavonols and their use as protein-binding-site fluorescence probes.
A comparative study is presented of competitive fluorescences of three flavonols, 3-hydroxyflavone, 3,3',4',7-tetrahydroxyflavone (fisetin), and 4'-diethylamino-3-hydroxyflavone (DHF). The normal fluorescence S1-->S0 (400-nm region) is largely replaced by the proton-transfer tautomer fluorescence S'1-->S'0 in the 550-nm region for all three of the flavonols