Fmrfamide
Mostrando 1-12 de 21 artigos, teses e dissertações.
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1. Evolution of flatworm central nervous systems: Insights from polyclads
The nervous systems of flatworms have diversified extensively as a consequence of the broad range of adaptations in the group. Here we examined the central nervous system (CNS) of 12 species of polyclad flatworms belonging to 11 different families by morphological and histological studies. These comparisons revealed that the overall organization and architec
Genet. Mol. Biol.. Publicado em: 2015-09
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2. Ultrastructural analysis of the dorsal body gland of the terrestrial snail Megalobulimus abbreviatus (Becquaert, 1948) = Análise ultraestrutural da glândula corpo dorsal do caracol terrestre Megalobulimus abbreviatus (Becquaert, 1948) / Análise ultraestrutural da glândula corpo dorsal do caracol terrestre Megalobulimus abbreviatus (Becquaert, 1948)
Foi analisada a ultraestrutura da glândula reprodutiva corpo dorsal (CD) de Megalobulimus abbreviatus. Imunoistoquímica para microscopia eletrônica foi utilizada para detectar peptídeos relacionados ao tetrapeptídeo FMRFamida nas terminações axonais existentes nessa glândula. Foi utilizada marcação neuronal retrógada com o intuito de localizar os
Publicado em: 2011
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3. Morphology, ultrastructure and immunohistochemistry of the midgut of Triatoma vitticeps (Hemiptera, Triatominae) / Morfologia, ultra-estrutura e imunohistoquímica do intestino médio de Triatoma vitticeps (Hemiptera, Triatominae)
Entre todos os animais, os insetos representam uma classe que conseguiu enorme sucesso na ocupação de vários nichos em diferentes ambientes na Terra. Este sucesso se deve, entre outros fatores, a adaptação a diferentes hábitos alimentares. Geralmente, o intestino dos insetos é dividido em intestino anterior, médio e posterior. O intestino médio é r
Publicado em: 2009
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4. Molecular cloning and functional expression of the first insect FMRFamide receptor
FMRFamide and FMRFamide-related neuropeptides are extremely widespread and abundant in invertebrates and have numerous important functions. Here, we have cloned a Drosophila orphan receptor, and stably expressed it in Chinese hamster ovary cells. Screening of a peptide library revealed that the receptor reacted with high affinity to FMRFamide (EC50, 6 × 10�
National Academy of Sciences.
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5. Modulation of potassium conductances by an endogenous neuropeptide in neurones of Aplysia californica.
1. Macroscopic and single-channel currents were recorded from voltage-clamped neurones in the abdominal and pleural ganglia of Aplysia californica in order to investigate conductance changes elicited by application of the endogenous peptide FMRFamide (Phe-Met-Arg-Phe-NH2) and related neuropeptides to the cell surface. 2. The Ca-dependent K current, IK(Ca), w
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6. Role of two different guanine nucleotide-binding proteins in the antagonistic modulation of the S-type K+ channel by cAMP and arachidonic acid metabolites in Aplysia sensory neurons.
The role of guanine nucleotide-binding proteins (G proteins) in the cAMP-dependent action of serotonin (5-HT) and the antagonistic action of the neuropeptide Phe-Met-Arg-Phe-NH2 (FMRF-amide), mediated by the lipoxygenase metabolites of arachidonic acid, was investigated in Aplysia sensory neurons. Intracellular injection of guanosine 5'-[gamma-thio]triphosph
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7. Suppression of calcium current by an endogenous neuropeptide in neurones of Aplysia californica.
1. Actions of the neuropeptide FMRFamide (Phe-Met-Arg-Phe-NH2) and its derivative YGG-FMRFamide (Tyr-Gly-Gly-Phe-Met-Arg-Phe-NH2) on Ca2+ current were examined in identified, voltage-clamped neurones in the abdominal ganglion of Aplysia californica. 2. 'Puffed' application of either peptide at concentrations of 1-50 microM was followed by a transient partial
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8. Identification in Drosophila melanogaster of the invertebrate G protein-coupled FMRFamide receptor
We here describe the cloning and characterization of the functionally active Drosophila melanogaster (Drm) FMRFamide receptor, which we designated as DrmFMRFa-R. The full-length ORF of a D. melanogaster orphan receptor, CG 2114 (Berkeley Drosophila Genome Project), was cloned from genomic DNA. This receptor is distantly related to mammalian thyroid-stimulati
National Academy of Sciences.
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9. Guanosine 5'-triphosphate analogue activates potassium current modulated by neurotransmitters in Aplysia neurones.
1. Identified neurones in the abdominal ganglion of Aplysia californica were voltage clamped in order to investigate how guanosine 5'-O-(3-thiotriphosphate) (GTP-gamma-S), a GTP analogue that irreversibly activates guanine nucleotide-binding (G) proteins, modifies activation by the neuropeptide FMRFamide (Phe-Met-Arg-Phe-NH2) of a slow K+ current resembling
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10. The peptide FMRFamide activates a divalent cation-conducting channel in heart muscle cells of the snail Lymnaea stagnalis.
1. Isolated Lymnaea stagnalis heart ventricle cells contain cation-conducting channels with properties characteristic of Ca2+ channels. These channels, which carry inward Na+ currents in the absence of Ca2+, are activated by the molluscan cardioactive peptides FMRFamide and FLRFamide, and are blocked by Co2+ ions. 2. FMRFamide also activated inward Ba2+ curr
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11. A Genetic and Molecular Analysis of the 46c Chromosomal Region Surrounding the Fmrfamide Neuropeptide Gene in Drosophila Melanogaster
We have analyzed the FMRFamide neuropeptide gene region of Drosophila melanogaster. This gene maps to the 46C region of chromosome 2R; this interval previously was not well characterized. For this genetic and molecular analysis, we have used X-ray mutagenesis, EMS mutagenesis, and the recently reported local P element transposition method. We identified four
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12. Peptidergic modulation of patterned motor activity in identified neurons of Helisoma
The neuroactive peptides SCPB (small cardioactive peptide B) and FMRFamide (Phe-Met-Arg-Phe-NH2), both originally isolated from molluscs, have potent modulatory effects upon the production of patterned motor activity in identified neurons (e.g., B5 and B19) in the buccal ganglia of the snail Helisoma. Such patterned motor activity has previously been shown t