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Mostrando 1-12 de 15112 artigos, teses e dissertações.
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1. ARTEMISININA E DERIVADOS: DESCOBERTA, ESTRATÉGIAS SINTÉTICAS E OBTENÇÃO INDUSTRIAL
Artemisinin, a natural sesquiterpene isolated from the Artemisia annua L. plant, represents a remarkable achievement in the treatment against malaria. Since its discovery in the 1970’s, researchers readily started synthesizing this complex natural product containing an unusual endoperoxide fragment. Despite various total syntheses reported, only in the las
Química Nova. Publicado em: 2022
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2. Dynamics of natural regeneration in a fragment of a Mixed Ombrophilous Forest in the upland region of Santa Catarina, Brazil
Resumo Este estudo teve como objetivo analisar as alterações temporais na composição florística e estrutura da regeneração em um remanescente de Floresta Ombrófila Mista sem intervenções há décadas, nos anos de 2012 e 2017. A área experimental foi composta por 20 parcelas circulares de 2,5 m de raio, onde foi realizada a quantificação dos rege
Ciência Florestal. Publicado em: 2022
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3. Ultrasound guided endoscopic combined Intrarenal surgery – 10 steps for the success
ABSTRACT Background: Endoscopic combined intrarenal surgery (ECIRS) has been used to treat complex kidney stones (1). The combined use of ultrasound (US) has the potential to improve safety and reduce radiation exposure, however, it is still underutilized (2). Objectives: Our objective is to describe, in a step-by-step manner, the ultrasound-guided ECIRS (
International braz j urol. Publicado em: 2022
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4. Polymorphisms in the heme oxygenase-1 and bone morphogenetic protein receptor type 1b genes and estimated glomerular filtration rate in Brazilian sickle cell anemia patients
ABSTRACT Introduction Mutations affecting genes involved in oxidative and signaling pathways may be associated with kidney disease in sickle cell anemia. We determined the allele and genotype frequencies of some polymorphisms in the promoter regions of the Heme Oxygenase-1 (HMOX1) [rs2071746 (A > T) and (GT)n repeats, short (S) and long (L) alleles] and Bon
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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5. Gene variants and serum levels of synaptic vesicle and presynaptic plasma membrane proteins in alcohol dependence and their relationship with impulsivity and temperament
ABSTRACT Background: Exocytosis-related gene variants have been suggested to be associated with externalizing behaviors. Objective: This study aimed to examine VAMP2 26 bp Ins\Del, synaptotagmin XI (Syt11) rs3820594 and 33-bp promoter, Syntaxin 1A (Syn-1A) rs1569061 and SNAP-25 rs1051312 and rs3746544 polymorphisms, their serum levels and their relationshi
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2021-04
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6. Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,
Abstract As the treatment of infectious and parasitic diseases improved, the prevalence of these conditions declined. However, with the expansion of the use of immunobiologicals, opportunistic infections have emerged, especially under atypical presentations. The present study reports the case of a patient treated with infliximab for Crohn's disease, who pres
An. Bras. Dermatol.. Publicado em: 2021-03
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7. MÉTODO DE TRIAGEM DE MICROGININAS EM CIANOBACTÉRIAS POR LC-MS/MS
Cyanobacteria produce a wide variety of bioactive compounds, making them a highly promising group in the search for novel molecules with pharmacological and biotechnological properties. Among these, microginins attract attention for being peptides which inhibit angiotensin-converting enzyme, turning them into potential targets for hypertension and congestive
Quím. Nova. Publicado em: 2020-12
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8. Genetic variability in peppers accessions based on morphological, biochemical and molecular traits
ABSTRACT The evaluation of genetic diversity among the accessions of a germplasm collection results in information about promising materials suitable for breeding programs. Thus, the goal of this work was to characterize Capsicum baccatum accessions from different Brazilian regions, based on morphological, biochemical and molecular traits, aiming to support
Bragantia. Publicado em: 2020-12
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9. Evaluation of ex vivo melanogenic response to UVB, UVA, and visible light in facial melasma and unaffected adjacent skin,
Abstract Background: The independent role of solar radiation in the differential melanogenesis between melasma and adjacent skin is unknown. Objectives: To assess the melanogenic responses of skin with facial melasma and of the adjacent skin to UVB, UVA, and visible light, in an ex vivo model. Methods: This was a quasi-experimental study involving 22 pati
An. Bras. Dermatol.. Publicado em: 2020-12
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10. Tillage systems and cover plants change organic fractions of phosphorus in oxisol of eastern Amazonia
ABSTRACT Due to the large extent of degraded areas in the Amazon, the use of conservation systems is very important to contain the advance of the agricultural frontier, and may favor the availability of nutrients such as phosphorus (P). This study evaluated effect of tillage systems on and cover plants distribution of organic P fractions (Po) in oxisol under
Bragantia. Publicado em: 2020-09
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11. STATISTICAL PROCESS CONTROL APPLIED TO MONITOR LOSSES IN THE MECHANIZED SUGARCANE HARVESTING
ABSTRACT The mechanized sugarcane harvesting process is considered one of the major economic bottlenecks, with low operational efficiency and, mainly, high losses of stalks left in the field. In order to minimize these problems and assist in the improvement of processes, this study aimed to evaluate the losses in the mechanized sugarcane harvesting using sta
Eng. Agríc.. Publicado em: 2020-08
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12. Psathyrella atlantica (Agaricales: Basidiomycota), a new species from Brazil
ABSTRACT Psathyrella atlantica is described based on material collected in an Atlantic Forest fragment in the state of Pernambuco, Northeast Brazil. It is characterized by slender, whitish and caespitose basidiomata; pileus with orange, small and floccose-squamulose veil remnants; presence of a persistent but fragile-membranous annulus; basidiospores 5-7 ×
Acta Bot. Bras.. Publicado em: 2020-06